Calcium in PDB 6k5p: Structure of Mosquito-Larvicidal Binary Toxin Receptor, CQM1

The structure of Structure of Mosquito-Larvicidal Binary Toxin Receptor, CQM1, PDB code: 6k5p was solved by V.Kumar, M.Sharma, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	29.83 / 1.81
Space group	P 21 21 21
Cell size a, b, c (Å), α, β, γ (°)	59.181, 191.486, 205.332, 90.00, 90.00, 90.00
R / Rfree (%)	18.3 / 22.7

The structure of Structure of Mosquito-Larvicidal Binary Toxin Receptor, CQM1 also contains other interesting chemical elements:

Cobalt	(Co)	2 atoms
Magnesium	(Mg)	4 atoms
Cadmium	(Cd)	14 atoms

The binding sites of Calcium atom in the Structure of Mosquito-Larvicidal Binary Toxin Receptor, CQM1 (pdb code 6k5p). This binding sites where shown within 5.0 Angstroms radius around Calcium atom.
In total 4 binding sites of Calcium where determined in the Structure of Mosquito-Larvicidal Binary Toxin Receptor, CQM1, PDB code: 6k5p:
Jump to Calcium binding site number: 1; 2; 3; 4;

Calcium binding site 1 out of 4 in the Structure of Mosquito-Larvicidal Binary Toxin Receptor, CQM1


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 1 of Structure of Mosquito-Larvicidal Binary Toxin Receptor, CQM1 within 5.0Å range: probe atom residue distance (Å) B Occ A:Ca603 b:19.5 occ:1.00 O A:HOH883 2.3 21.8 1.0 O A:HOH835 2.3 20.4 1.0 OE2 A:GLU210 2.4 19.4 1.0 O A:MET208 2.4 19.9 1.0 O A:HIS207 2.4 16.4 1.0 OD2 A:ASP173 2.5 22.2 1.0 OD1 A:ASN106 2.5 30.0 1.0 C A:MET208 3.2 21.5 1.0 CD A:GLU210 3.4 24.2 1.0 C A:HIS207 3.5 23.1 1.0 CG A:ASP173 3.5 24.4 1.0 CG A:ASN106 3.5 22.1 1.0 CA A:MET208 3.6 20.8 1.0 OE1 A:GLU210 3.7 20.7 1.0 CB A:ASP173 3.9 18.1 1.0 ND2 A:ASN106 4.0 16.7 1.0 N A:MET208 4.0 20.2 1.0 NE2 A:GLN166 4.1 17.7 1.0 O A:HOH893 4.2 21.6 1.0 O A:ASN106 4.3 20.2 1.0 N A:PHE209 4.3 17.9 1.0 O A:LEU174 4.3 22.6 1.0 OD1 A:ASP173 4.6 24.8 1.0 CA A:HIS207 4.7 18.6 1.0 CG A:GLU210 4.8 21.4 1.0 CA A:PHE209 4.8 21.2 1.0 CB A:ASN106 4.8 23.0 1.0 CB A:HIS207 4.8 20.0 1.0 CG A:GLN166 4.9 20.6 1.0 CD A:GLN166 4.9 18.5 1.0 C A:PHE209 4.9 22.8 1.0 CA A:ASP173 4.9 16.6 1.0

Calcium binding site 2 out of 4 in the Structure of Mosquito-Larvicidal Binary Toxin Receptor, CQM1


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 2 of Structure of Mosquito-Larvicidal Binary Toxin Receptor, CQM1 within 5.0Å range: probe atom residue distance (Å) B Occ B:Ca603 b:19.7 occ:1.00 O B:HOH812 2.3 25.2 1.0 O B:HOH830 2.4 20.5 1.0 OE2 B:GLU210 2.4 23.3 1.0 O B:HIS207 2.4 20.3 1.0 OD2 B:ASP173 2.5 25.6 1.0 OD1 B:ASN106 2.5 20.9 1.0 O B:MET208 2.6 18.6 1.0 C B:MET208 3.2 21.4 1.0 CD B:GLU210 3.4 25.6 1.0 C B:HIS207 3.5 23.6 1.0 CG B:ASP173 3.5 28.7 1.0 CG B:ASN106 3.5 27.2 1.0 CA B:MET208 3.6 17.3 1.0 OE1 B:GLU210 3.8 25.4 1.0 CB B:ASP173 3.9 18.6 1.0 ND2 B:ASN106 3.9 20.9 1.0 N B:MET208 4.0 24.2 1.0 NE2 B:GLN166 4.1 21.7 1.0 O B:ASN106 4.2 19.2 1.0 N B:PHE209 4.3 20.7 1.0 O B:HOH779 4.3 25.1 1.0 O B:LEU174 4.3 23.8 1.0 OD1 B:ASP173 4.6 31.3 1.0 CA B:HIS207 4.7 20.1 1.0 CB B:HIS207 4.7 22.3 1.0 CG B:GLU210 4.8 22.2 1.0 CB B:ASN106 4.8 27.1 1.0 CA B:PHE209 4.8 20.0 1.0 CA B:ASP173 4.9 18.1 1.0 CG B:GLN166 4.9 21.9 1.0 CD B:GLN166 4.9 25.0 1.0 C B:PHE209 4.9 20.7 1.0 CB B:MET208 5.0 23.2 1.0 CD2 B:LEU164 5.0 21.3 1.0

Calcium binding site 3 out of 4 in the Structure of Mosquito-Larvicidal Binary Toxin Receptor, CQM1


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 3 of Structure of Mosquito-Larvicidal Binary Toxin Receptor, CQM1 within 5.0Å range: probe atom residue distance (Å) B Occ C:Ca603 b:23.0 occ:1.00 OE2 C:GLU210 2.4 27.3 1.0 O C:MET208 2.4 30.2 1.0 O C:HIS207 2.4 21.0 1.0 O C:HOH739 2.4 27.5 1.0 OD1 C:ASN106 2.4 29.4 1.0 O C:HOH776 2.5 19.5 1.0 OD2 C:ASP173 2.5 26.2 1.0 C C:MET208 3.2 28.2 1.0 CD C:GLU210 3.3 24.2 1.0 CG C:ASN106 3.5 23.6 1.0 C C:HIS207 3.5 29.6 1.0 CG C:ASP173 3.5 22.9 1.0 OE1 C:GLU210 3.6 27.8 1.0 CA C:MET208 3.6 24.2 1.0 CB C:ASP173 3.9 23.4 1.0 ND2 C:ASN106 3.9 21.5 1.0 N C:MET208 4.0 26.5 1.0 NE2 C:GLN166 4.2 28.1 1.0 O C:ASN106 4.2 25.8 1.0 N C:PHE209 4.3 28.0 1.0 O C:LEU174 4.3 35.9 1.0 O C:HOH954 4.4 29.4 1.0 OD1 C:ASP173 4.6 28.5 1.0 CG C:GLU210 4.7 23.7 1.0 CA C:HIS207 4.7 23.0 1.0 CB C:ASN106 4.7 19.2 1.0 CB C:HIS207 4.8 23.2 1.0 CA C:PHE209 4.8 28.5 1.0 CG C:GLN166 4.9 19.2 1.0 C C:PHE209 4.9 27.0 1.0 CA C:ASP173 4.9 23.4 1.0 O C:PHE209 5.0 24.5 1.0 CA C:ASN106 5.0 21.2 1.0 CD C:GLN166 5.0 24.2 1.0

Calcium binding site 4 out of 4 in the Structure of Mosquito-Larvicidal Binary Toxin Receptor, CQM1


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 4 of Structure of Mosquito-Larvicidal Binary Toxin Receptor, CQM1 within 5.0Å range: probe atom residue distance (Å) B Occ D:Ca603 b:17.4 occ:1.00 OE2 D:GLU210 2.3 22.4 1.0 O D:HIS207 2.4 17.3 1.0 O D:HOH756 2.4 21.3 1.0 O D:MET208 2.4 21.5 1.0 OD1 D:ASN106 2.5 22.7 1.0 O D:HOH791 2.5 17.8 1.0 OD2 D:ASP173 2.5 22.5 1.0 C D:MET208 3.2 22.1 1.0 CD D:GLU210 3.4 22.5 1.0 C D:HIS207 3.5 22.9 1.0 CG D:ASP173 3.5 22.5 1.0 CG D:ASN106 3.5 21.4 1.0 CA D:MET208 3.6 20.4 1.0 OE1 D:GLU210 3.8 25.9 1.0 CB D:ASP173 3.9 18.1 1.0 ND2 D:ASN106 4.0 21.3 1.0 N D:MET208 4.0 22.3 1.0 NE2 D:GLN166 4.2 19.7 1.0 O D:ASN106 4.2 18.6 1.0 N D:PHE209 4.3 24.1 1.0 O D:HOH919 4.3 22.9 1.0 O D:LEU174 4.4 21.6 1.0 OD1 D:ASP173 4.6 27.3 1.0 CA D:HIS207 4.7 19.6 1.0 CG D:GLU210 4.7 14.7 1.0 CG D:GLN166 4.8 18.9 1.0 CB D:HIS207 4.8 21.1 1.0 CB D:ASN106 4.8 19.7 1.0 CA D:PHE209 4.8 24.8 1.0 CA D:ASP173 4.9 19.5 1.0 CD2 D:LEU164 4.9 22.6 1.0 C D:PHE209 5.0 22.2 1.0 CD D:GLN166 5.0 22.1 1.0 CB D:MET208 5.0 19.4 1.0

M.Sharma, V.Kumar. Crystal Structure of Binab Toxin Receptor (CQM1) Protein and Molecular Dynamics Simulations Reveal the Role of Unique Ca(II) Ion. Int.J.Biol.Macromol. 2019.
ISSN: ISSN 0141-8130
PubMed: 31449868
DOI: 10.1016/J.IJBIOMAC.2019.08.126