Calcium in PDB 6kgb: Crystal Structure of E61K Mutated Transthyretin

The structure of Crystal Structure of E61K Mutated Transthyretin, PDB code: 6kgb was solved by T.Yokoyama, M.Mizuguchi, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	42.80 / 1.30
Space group	P 21 21 2
Cell size a, b, c (Å), α, β, γ (°)	42.538, 85.597, 64.419, 90.00, 90.00, 90.00
R / Rfree (%)	16.1 / 17.7

The binding sites of Calcium atom in the Crystal Structure of E61K Mutated Transthyretin (pdb code 6kgb). This binding sites where shown within 5.0 Angstroms radius around Calcium atom.
In total only one binding site of Calcium was determined in the Crystal Structure of E61K Mutated Transthyretin, PDB code: 6kgb:

Calcium binding site 1 out of 1 in the Crystal Structure of E61K Mutated Transthyretin


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 1 of Crystal Structure of E61K Mutated Transthyretin within 5.0Å range: probe atom residue distance (Å) B Occ A:Ca201 b:54.8 occ:1.00 OE1 A:GLU66 2.5 26.2 1.0 OD1 A:ASP99 2.7 54.7 1.0 O A:ASP99 3.0 33.8 1.0 CD A:GLU66 3.3 24.6 1.0 OE2 A:GLU66 3.4 25.5 1.0 O A:HOH346 3.7 43.4 1.0 O A:HOH311 3.8 34.8 1.0 C A:ASP99 3.9 35.0 1.0 O A:HOH343 3.9 37.5 1.0 CG A:ASP99 3.9 51.9 1.0 CA A:ASP99 4.1 33.9 1.0 CG A:GLU66 4.6 25.1 1.0 CB A:ASP99 4.6 42.5 1.0 OD2 A:ASP99 4.9 55.4 1.0

T.Murakami, T.Yokoyama, M.Mizuguchi, S.Tone, S.Takaku, K.Sango, H.Nishimura, K.Watabe, Y.Sunada. A Low Amyloidogenic E61K Transthyretin Mutation May Cause Familial Amyloid Polyneuropathy. J.Neurochem. 2020.
ISSN: ESSN 1471-4159
PubMed: 32852783
DOI: 10.1111/JNC.15162