Calcium in PDB 6ln6: Cryoem Structure of SERCA2B T1032STOP in E1-2CA2+-Amppcp (CLASS2)

All present enzymatic activity of Cryoem Structure of SERCA2B T1032STOP in E1-2CA2+-Amppcp (CLASS2):
7.2.2.10;

The structure of Cryoem Structure of SERCA2B T1032STOP in E1-2CA2+-Amppcp (CLASS2) also contains other interesting chemical elements:

Magnesium

(Mg)

1 atom

The binding sites of Calcium atom in the Cryoem Structure of SERCA2B T1032STOP in E1-2CA2+-Amppcp (CLASS2) (pdb code 6ln6). This binding sites where shown within 5.0 Angstroms radius around Calcium atom.
In total 2 binding sites of Calcium where determined in the Cryoem Structure of SERCA2B T1032STOP in E1-2CA2+-Amppcp (CLASS2), PDB code: 6ln6:
Jump to Calcium binding site number: 1; 2;

Calcium binding site 1 out of 2 in the Cryoem Structure of SERCA2B T1032STOP in E1-2CA2+-Amppcp (CLASS2)


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 1 of Cryoem Structure of SERCA2B T1032STOP in E1-2CA2+-Amppcp (CLASS2) within 5.0Å range: probe atom residue distance (Å) B Occ A:Ca2003 b:19.8 occ:1.00 OE2 A:GLU309 2.3 24.3 1.0 OE1 A:GLU309 2.4 24.3 1.0 OD1 A:ASN795 2.4 18.5 1.0 OD2 A:ASP799 2.4 19.1 1.0 O A:ILE307 2.4 22.2 1.0 O A:VAL304 2.5 20.3 1.0 O A:ALA305 2.5 20.1 1.0 CD A:GLU309 2.7 24.3 1.0 C A:ALA305 3.2 20.1 1.0 CG A:ASN795 3.5 18.5 1.0 CG A:ASP799 3.5 19.1 1.0 C A:ILE307 3.6 22.2 1.0 C A:VAL304 3.6 20.3 1.0 CA A:ALA305 3.7 20.1 1.0 N A:ILE307 3.9 22.2 1.0 CB A:ASP799 3.9 19.1 1.0 N A:ALA305 4.1 20.1 1.0 CG A:GLU309 4.2 24.3 1.0 N A:ALA306 4.3 21.5 1.0 CA A:ILE307 4.3 22.2 1.0 CB A:ASN795 4.3 18.5 1.0 ND2 A:ASN795 4.4 18.5 1.0 ND2 A:ASN767 4.4 17.3 1.0 C A:ALA306 4.5 21.5 1.0 N A:GLU309 4.5 24.3 1.0 OD1 A:ASP799 4.6 19.1 1.0 N A:PRO308 4.6 23.3 1.0 CA A:ALA306 4.8 21.5 1.0 CB A:ILE307 4.8 22.2 1.0 CA A:PRO308 4.8 23.3 1.0 CA A:VAL304 4.9 20.3 1.0 CA A:ASN795 4.9 18.5 1.0 O A:ASN795 5.0 18.5 1.0 CB A:GLU309 5.0 24.3 1.0

Calcium binding site 2 out of 2 in the Cryoem Structure of SERCA2B T1032STOP in E1-2CA2+-Amppcp (CLASS2)


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 2 of Cryoem Structure of SERCA2B T1032STOP in E1-2CA2+-Amppcp (CLASS2) within 5.0Å range: probe atom residue distance (Å) B Occ A:Ca2004 b:15.9 occ:1.00 OE2 A:GLU907 2.3 15.6 1.0 OD1 A:ASP799 2.4 19.1 1.0 OE2 A:GLU770 2.4 17.9 1.0 OD1 A:ASN767 2.4 17.3 1.0 OG1 A:THR798 2.4 17.4 1.0 CG A:ASP799 3.3 19.1 1.0 CB A:THR798 3.4 17.4 1.0 CD A:GLU770 3.5 17.9 1.0 CD A:GLU907 3.5 15.6 1.0 CG A:ASN767 3.6 17.3 1.0 OD2 A:ASP799 3.7 19.1 1.0 OG A:SER766 3.7 17.1 1.0 OE1 A:GLU770 3.9 17.9 1.0 O A:VAL794 4.0 17.0 1.0 OE1 A:GLU907 4.2 15.6 1.0 C A:THR798 4.2 17.4 1.0 N A:ASP799 4.2 19.1 1.0 ND2 A:ASN767 4.3 17.3 1.0 CG2 A:THR798 4.4 17.4 1.0 CA A:THR798 4.4 17.4 1.0 CB A:ASP799 4.5 19.1 1.0 O A:THR798 4.5 17.4 1.0 CG A:GLU907 4.6 15.6 1.0 CB A:SER766 4.6 17.1 1.0 N A:ASN767 4.7 17.3 1.0 CA A:ASN767 4.7 17.3 1.0 CG A:GLU770 4.7 17.9 1.0 CB A:ASN767 4.7 17.3 1.0 C A:SER766 4.7 17.1 1.0 CA A:ASP799 4.7 19.1 1.0 O A:SER766 4.7 17.1 1.0 O A:ALA305 5.0 20.1 1.0 C A:VAL794 5.0 17.0 1.0

Y.Zhang, M.Inoue, A.Tsutsumi, S.Watanabe, T.Nishizawa, K.Nagata, M.Kikkawa, K.Inaba. Cryo-Em Structures of SERCA2B Reveal the Mechanism of Regulation By the Luminal Extension Tail. Sci Adv V. 6 B0147 2020.
ISSN: ESSN 2375-2548
PubMed: 32851169
DOI: 10.1126/SCIADV.ABB0147