Calcium in PDB 6lp1: Crystal Structure of Acetate:Succinate Coa Transferase (Asct) From Trypanosoma Brucei.

Enzymatic activity of Crystal Structure of Acetate:Succinate Coa Transferase (Asct) From Trypanosoma Brucei.

All present enzymatic activity of Crystal Structure of Acetate:Succinate Coa Transferase (Asct) From Trypanosoma Brucei.:
2.8.3.5;

Protein crystallography data

The structure of Crystal Structure of Acetate:Succinate Coa Transferase (Asct) From Trypanosoma Brucei., PDB code: 6lp1 was solved by K.Mochizuki, D.K.Inaoka, T.Shiba, K.Fukuda, H.Kurasawa, M.Mazet, Y.Millerioux, F.Bringaud, M.Boshart, E.O.Balogun, S.Harada, K.Hirayama, K.Kita, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 19.97 / 2.01
Space group P 21 21 21
Cell size a, b, c (Å), α, β, γ (°) 59.886, 164.635, 187.573, 90.00, 90.00, 90.00
R / Rfree (%) 22.5 / 27.9

Calcium Binding Sites:

The binding sites of Calcium atom in the Crystal Structure of Acetate:Succinate Coa Transferase (Asct) From Trypanosoma Brucei. (pdb code 6lp1). This binding sites where shown within 5.0 Angstroms radius around Calcium atom.
In total 4 binding sites of Calcium where determined in the Crystal Structure of Acetate:Succinate Coa Transferase (Asct) From Trypanosoma Brucei., PDB code: 6lp1:
Jump to Calcium binding site number: 1; 2; 3; 4;

Calcium binding site 1 out of 4 in 6lp1

Go back to Calcium Binding Sites List in 6lp1
Calcium binding site 1 out of 4 in the Crystal Structure of Acetate:Succinate Coa Transferase (Asct) From Trypanosoma Brucei.


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 1 of Crystal Structure of Acetate:Succinate Coa Transferase (Asct) From Trypanosoma Brucei. within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Ca501

b:40.7
occ:1.00
 OD2 A:ASP239 2.5 22.3 1.0
O A:GLN211 2.5 18.8 1.0
OD1 A:ASP239 2.9 22.9 1.0
CG A:ASP239 3.0 22.6 1.0
C A:GLN211 3.6 22.3 1.0
O A:HOH626 4.1 16.9 1.0
O A:GLY210 4.3 19.4 1.0
N A:THR212 4.5 21.8 1.0
CA A:THR212 4.5 21.2 1.0
CG1 A:VAL213 4.5 24.2 1.0
CA A:GLN211 4.5 24.2 1.0
CB A:ASP239 4.5 22.0 1.0
N A:VAL213 4.7 21.2 1.0
O A:HOH675 4.8 25.1 1.0
O B:HOH673 4.8 28.7 1.0
O A:TYR237 4.8 19.4 1.0

Calcium binding site 2 out of 4 in 6lp1

Go back to Calcium Binding Sites List in 6lp1
Calcium binding site 2 out of 4 in the Crystal Structure of Acetate:Succinate Coa Transferase (Asct) From Trypanosoma Brucei.


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 2 of Crystal Structure of Acetate:Succinate Coa Transferase (Asct) From Trypanosoma Brucei. within 5.0Å range:
probe atom residue distance (Å) B Occ
B:Ca501

b:64.3
occ:1.00
 O B:GLN211 2.6 23.5 1.0
OD2 B:ASP239 2.9 24.7 1.0
OD1 B:ASP239 3.3 24.7 1.0
CG B:ASP239 3.5 25.1 1.0
O A:HOH693 3.6 23.7 1.0
O A:HOH648 3.6 20.2 1.0
C B:GLN211 3.7 24.6 1.0
O B:GLY210 4.0 22.8 1.0
O B:HOH647 4.4 19.1 1.0
CG1 B:VAL213 4.5 26.8 1.0
O B:TYR237 4.6 18.8 1.0
CA B:GLN211 4.6 26.7 1.0
N B:THR212 4.6 22.8 1.0
CA B:THR212 4.6 22.7 1.0
CB B:ASP239 5.0 23.9 1.0
N B:VAL213 5.0 23.3 1.0
C B:GLY210 5.0 24.5 1.0

Calcium binding site 3 out of 4 in 6lp1

Go back to Calcium Binding Sites List in 6lp1
Calcium binding site 3 out of 4 in the Crystal Structure of Acetate:Succinate Coa Transferase (Asct) From Trypanosoma Brucei.


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 3 of Crystal Structure of Acetate:Succinate Coa Transferase (Asct) From Trypanosoma Brucei. within 5.0Å range:
probe atom residue distance (Å) B Occ
C:Ca501

b:47.8
occ:1.00
 O C:GLN211 2.6 27.2 1.0
OD1 C:ASP239 2.6 24.6 1.0
OD2 C:ASP239 2.7 23.4 1.0
CG C:ASP239 3.0 23.4 1.0
C C:GLN211 3.8 25.7 1.0
O C:GLY210 4.5 21.1 1.0
CB C:ASP239 4.5 21.3 1.0
CA C:THR212 4.6 23.4 1.0
N C:THR212 4.6 24.4 1.0
O C:TYR237 4.6 20.8 1.0
CG1 C:VAL213 4.6 24.5 1.0
CA C:GLN211 4.7 26.9 1.0
N C:VAL213 4.8 24.5 1.0

Calcium binding site 4 out of 4 in 6lp1

Go back to Calcium Binding Sites List in 6lp1
Calcium binding site 4 out of 4 in the Crystal Structure of Acetate:Succinate Coa Transferase (Asct) From Trypanosoma Brucei.


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 4 of Crystal Structure of Acetate:Succinate Coa Transferase (Asct) From Trypanosoma Brucei. within 5.0Å range:
probe atom residue distance (Å) B Occ
D:Ca501

b:39.8
occ:1.00
 OD1 D:ASP239 2.5 18.9 1.0
O D:GLN211 2.5 22.3 1.0
OD2 D:ASP239 2.6 19.8 1.0
CG D:ASP239 2.9 19.6 1.0
C D:GLN211 3.6 23.5 1.0
O D:HOH619 4.0 14.1 1.0
O D:GLY210 4.2 23.4 1.0
CB D:ASP239 4.4 20.3 1.0
CA D:THR212 4.5 21.0 1.0
N D:THR212 4.5 21.5 1.0
N D:VAL213 4.6 19.5 1.0
CA D:GLN211 4.6 24.7 1.0
O D:HOH653 4.7 24.2 1.0
CG2 D:VAL213 4.8 19.0 1.0
O D:TYR237 4.8 18.2 1.0
O D:HOH611 4.9 36.8 1.0
C D:THR212 5.0 20.8 1.0

Reference:

K.Mochizuki, D.K.Inaoka, M.Mazet, T.Shiba, K.Fukuda, H.Kurasawa, Y.Millerioux, M.Boshart, E.O.Balogun, S.Harada, K.Hirayama, F.Bringaud, K.Kita. The Asct/Scs Cycle Fuels Mitochondrial Atp and Acetate Production in Trypanosoma Brucei. Biochim Biophys Acta V.1861 48283 2020BIOENERG.
ISSN: ISSN 1879-2650
PubMed: 32763239
DOI: 10.1016/J.BBABIO.2020.148283
Page generated: Sat Dec 12 06:34:08 2020

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