Calcium in PDB 6m7t: Human Dna Polymerase Eta in A Non-Productive Ternary Complex with CA2+ and Dttp Oppositing Cda

Enzymatic activity of Human Dna Polymerase Eta in A Non-Productive Ternary Complex with CA2+ and Dttp Oppositing Cda

All present enzymatic activity of Human Dna Polymerase Eta in A Non-Productive Ternary Complex with CA2+ and Dttp Oppositing Cda:
2.7.7.7;

Protein crystallography data

The structure of Human Dna Polymerase Eta in A Non-Productive Ternary Complex with CA2+ and Dttp Oppositing Cda, PDB code: 6m7t was solved by P.Weng, Y.Gao, W.Yang, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 29.73 / 2.80
Space group P 21 21 21
Cell size a, b, c (Å), α, β, γ (°) 65.650, 80.930, 140.380, 90.00, 90.00, 90.00
R / Rfree (%) 22 / 26.1

Other elements in 6m7t:

The structure of Human Dna Polymerase Eta in A Non-Productive Ternary Complex with CA2+ and Dttp Oppositing Cda also contains other interesting chemical elements:

Nickel (Ni) 1 atom

Calcium Binding Sites:

The binding sites of Calcium atom in the Human Dna Polymerase Eta in A Non-Productive Ternary Complex with CA2+ and Dttp Oppositing Cda (pdb code 6m7t). This binding sites where shown within 5.0 Angstroms radius around Calcium atom.
In total only one binding site of Calcium was determined in the Human Dna Polymerase Eta in A Non-Productive Ternary Complex with CA2+ and Dttp Oppositing Cda, PDB code: 6m7t:

Calcium binding site 1 out of 1 in 6m7t

Go back to Calcium Binding Sites List in 6m7t
Calcium binding site 1 out of 1 in the Human Dna Polymerase Eta in A Non-Productive Ternary Complex with CA2+ and Dttp Oppositing Cda


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 1 of Human Dna Polymerase Eta in A Non-Productive Ternary Complex with CA2+ and Dttp Oppositing Cda within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Ca503

b:55.7
occ:1.00
 O A:MET14 2.1 61.2 1.0
OD1 A:ASP115 2.2 50.0 1.0
O2G A:TTP502 2.3 52.9 1.0
O1B A:TTP502 2.3 49.7 1.0
O1A A:TTP502 2.4 48.2 1.0
OD1 A:ASP13 2.5 65.9 1.0
PB A:TTP502 3.2 47.0 1.0
C A:MET14 3.3 59.8 1.0
CG A:ASP115 3.4 51.6 1.0
CG A:ASP13 3.4 55.5 1.0
PA A:TTP502 3.5 47.3 1.0
PG A:TTP502 3.5 51.8 1.0
O3A A:TTP502 3.5 56.7 1.0
O3B A:TTP502 3.6 55.8 1.0
OD2 A:ASP13 3.6 54.4 1.0
OD2 A:ASP115 4.0 65.3 1.0
N A:MET14 4.0 59.0 1.0
C5' A:TTP502 4.1 42.9 1.0
CA A:MET14 4.1 49.5 1.0
N A:ASP15 4.3 59.0 1.0
N A:CYS16 4.3 53.8 1.0
O1G A:TTP502 4.4 59.6 1.0
O5' A:TTP502 4.4 54.3 1.0
CA A:ASP15 4.4 52.6 1.0
CB A:ASP115 4.5 47.2 1.0
CB A:MET14 4.5 42.2 1.0
C A:ASP13 4.5 55.7 1.0
C A:ASP15 4.6 57.2 1.0
O3G A:TTP502 4.6 45.5 1.0
N A:PHE17 4.6 53.0 1.0
NZ A:LYS231 4.6 55.2 1.0
O2B A:TTP502 4.6 60.5 1.0
O2A A:TTP502 4.6 57.2 1.0
CB A:ASP13 4.8 42.8 1.0
CB A:PHE17 4.8 42.6 1.0

Reference:

P.J.Weng, Y.Gao, M.T.Gregory, P.Wang, Y.Wang, W.Yang. Bypassing A 8,5'-Cyclo-2'-Deoxyadenosine Lesion By Human Dna Polymerase Eta at Atomic Resolution. Proc. Natl. Acad. Sci. V. 115 10660 2018U.S.A..
ISSN: ESSN 1091-6490
PubMed: 30275308
DOI: 10.1073/PNAS.1812856115
Page generated: Sat Dec 12 06:48:07 2020

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