Calcium in PDB 6mf2: Improved Model of Human Coagulation Factor VIII

Protein crystallography data

The structure of Improved Model of Human Coagulation Factor VIII, PDB code: 6mf2 was solved by I.W.Smith, P.C.Spiegel, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 57.36 / 3.61
Space group P 41 21 2
Cell size a, b, c (Å), α, β, γ (°) 134.569, 134.569, 359.496, 90.00, 90.00, 90.00
R / Rfree (%) 25.2 / 28.4

Other elements in 6mf2:

The structure of Improved Model of Human Coagulation Factor VIII also contains other interesting chemical elements:

Copper (Cu) 1 atom
Zinc (Zn) 1 atom

Calcium Binding Sites:

The binding sites of Calcium atom in the Improved Model of Human Coagulation Factor VIII (pdb code 6mf2). This binding sites where shown within 5.0 Angstroms radius around Calcium atom.
In total only one binding site of Calcium was determined in the Improved Model of Human Coagulation Factor VIII, PDB code: 6mf2:

Calcium binding site 1 out of 1 in 6mf2

Go back to Calcium Binding Sites List in 6mf2
Calcium binding site 1 out of 1 in the Improved Model of Human Coagulation Factor VIII


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 1 of Improved Model of Human Coagulation Factor VIII within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Ca2410

b:27.0
occ:1.00
OD1 A:ASP126 2.5 43.5 1.0
OD1 A:ASP125 2.5 40.3 1.0
O A:LYS107 2.7 28.5 1.0
OD2 A:ASP125 3.0 34.5 1.0
O A:GLU122 3.0 53.2 1.0
CG A:ASP125 3.1 39.3 1.0
CG A:ASP126 3.6 53.4 1.0
C A:LYS107 3.9 31.5 1.0
OD2 A:ASP126 3.9 56.8 1.0
CB A:GLU110 4.0 32.8 1.0
OD2 A:ASP116 4.1 44.0 1.0
C A:GLU122 4.2 51.8 1.0
N A:GLY111 4.5 29.8 1.0
CD A:LYS107 4.5 28.0 1.0
O A:ALA112 4.5 51.2 1.0
CB A:ASP125 4.6 43.0 1.0
N A:GLU110 4.6 31.8 1.0
OE1 A:GLU110 4.6 29.9 1.0
N A:ASP126 4.7 45.0 1.0
CA A:LYS123 4.7 50.9 1.0
CA A:LYS107 4.8 32.8 1.0
CA A:GLU110 4.8 29.9 1.0
N A:ALA108 4.8 35.7 1.0
CB A:ASP126 4.8 56.8 1.0
CA A:ALA108 4.9 42.3 1.0
N A:LYS123 4.9 49.5 1.0
NZ A:LYS107 5.0 40.0 1.0
CA A:ASP126 5.0 48.5 1.0
CD A:GLU110 5.0 29.4 1.0

Reference:

I.W.Smith, A.E.D'aquino, C.W.Coyle, A.Fedanov, E.T.Parker, G.Denning, H.T.Spencer, P.Lollar, C.B.Doering, P.C.Spiegel Jr.. The 3.2 Angstrom Structure of A Bioengineered Variant of Blood Coagulation Factor VIII Indicates Two Conformations of the C2 Domain. J.Thromb.Haemost. 2019.
ISSN: ESSN 1538-7836
PubMed: 31454152
DOI: 10.1111/JTH.14621
Page generated: Sat Dec 12 06:58:22 2020

Last articles

Zn in 7VD8
Zn in 7V1R
Zn in 7V1Q
Zn in 7VPF
Zn in 7T85
Zn in 7T5F
Zn in 7NF9
Zn in 7M4M
Zn in 7M4O
Zn in 7M4N
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy