Calcium in PDB 6n23: BEST1 in A Calcium-Bound Inactivated State

The binding sites of Calcium atom in the BEST1 in A Calcium-Bound Inactivated State (pdb code 6n23). This binding sites where shown within 5.0 Angstroms radius around Calcium atom.
In total 5 binding sites of Calcium where determined in the BEST1 in A Calcium-Bound Inactivated State, PDB code: 6n23:
Jump to Calcium binding site number: 1; 2; 3; 4; 5;

Calcium binding site 1 out of 5 in the BEST1 in A Calcium-Bound Inactivated State


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 1 of BEST1 in A Calcium-Bound Inactivated State within 5.0Å range: probe atom residue distance (Å) B Occ A:Ca501 b:80.3 occ:1.00 O A:ASN296 2.5 80.3 1.0 O E:ALA10 2.5 80.3 1.0 O A:GLN293 2.5 80.3 1.0 OD2 A:ASP301 2.6 82.9 1.0 OD1 A:ASP304 2.6 80.3 1.0 OD2 A:ASP304 2.7 80.3 1.0 CG A:ASP304 3.0 80.3 1.0 C A:ASN296 3.5 80.3 1.0 CG A:ASP301 3.6 82.9 1.0 C A:GLN293 3.6 80.3 1.0 C E:ALA10 3.6 80.3 1.0 CA A:GLN293 4.1 80.3 1.0 CB A:ASP301 4.1 82.9 1.0 N A:ASN296 4.4 80.3 1.0 O E:VAL9 4.4 80.3 1.0 CA A:ASN296 4.4 80.3 1.0 N A:PRO297 4.4 80.3 1.0 CA A:PRO297 4.4 80.3 1.0 CB A:ASP304 4.5 80.3 1.0 O A:GLU292 4.5 80.3 1.0 OD1 A:ASP301 4.5 82.9 1.0 N E:ASP11 4.5 85.3 1.0 CA E:ALA10 4.5 80.3 1.0 CA E:ASP11 4.5 85.3 1.0 CG A:GLN293 4.5 80.3 1.0 CB A:ASN296 4.6 80.3 1.0 N A:GLY299 4.6 80.3 1.0 N A:LEU294 4.6 80.3 1.0 CA A:GLY299 4.8 80.3 1.0 N A:ASP301 4.9 82.9 1.0 CB A:GLN293 4.9 80.3 1.0 C A:PRO297 5.0 80.3 1.0 C E:ASP11 5.0 85.3 1.0

Calcium binding site 2 out of 5 in the BEST1 in A Calcium-Bound Inactivated State


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 2 of BEST1 in A Calcium-Bound Inactivated State within 5.0Å range: probe atom residue distance (Å) B Occ B:Ca501 b:80.3 occ:1.00 O A:ALA10 2.5 80.3 1.0 O B:GLN293 2.5 80.3 1.0 OD2 B:ASP301 2.5 83.7 1.0 O B:ASN296 2.5 80.3 1.0 OD1 B:ASP304 2.7 80.3 1.0 OD2 B:ASP304 2.7 80.3 1.0 CG B:ASP304 3.1 80.3 1.0 C B:GLN293 3.5 80.3 1.0 CG B:ASP301 3.5 83.7 1.0 C B:ASN296 3.6 80.3 1.0 C A:ALA10 3.6 80.3 1.0 CA B:GLN293 4.0 80.3 1.0 CB B:ASP301 4.1 83.7 1.0 N B:ASN296 4.4 80.3 1.0 O A:VAL9 4.4 80.3 1.0 O B:GLU292 4.4 80.3 1.0 CA B:ASN296 4.4 80.3 1.0 N B:PRO297 4.5 80.3 1.0 OD1 B:ASP301 4.5 83.7 1.0 N A:ASP11 4.5 86.0 1.0 CA B:PRO297 4.5 80.3 1.0 CA A:ALA10 4.5 80.3 1.0 CG B:GLN293 4.5 80.3 1.0 CA A:ASP11 4.5 86.0 1.0 CB B:ASN296 4.6 80.3 1.0 CB B:ASP304 4.6 80.3 1.0 N B:LEU294 4.6 80.3 1.0 N B:GLY299 4.7 80.3 1.0 CB B:GLN293 4.9 80.3 1.0 CA B:GLY299 4.9 80.3 1.0 N B:ASP301 5.0 83.7 1.0 C A:ASP11 5.0 86.0 1.0

Calcium binding site 3 out of 5 in the BEST1 in A Calcium-Bound Inactivated State


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 3 of BEST1 in A Calcium-Bound Inactivated State within 5.0Å range: probe atom residue distance (Å) B Occ C:Ca501 b:80.3 occ:1.00 O C:ASN296 2.5 80.3 1.0 O C:GLN293 2.5 80.3 1.0 O B:ALA10 2.5 80.3 1.0 OD2 C:ASP301 2.6 83.9 1.0 OD1 C:ASP304 2.7 80.3 1.0 OD2 C:ASP304 2.8 80.3 1.0 CG C:ASP304 3.1 80.3 1.0 C C:GLN293 3.5 80.3 1.0 C C:ASN296 3.5 80.3 1.0 CG C:ASP301 3.6 83.9 1.0 C B:ALA10 3.6 80.3 1.0 CA C:GLN293 4.0 80.3 1.0 CB C:ASP301 4.2 83.9 1.0 N C:ASN296 4.3 80.3 1.0 CA C:ASN296 4.3 80.3 1.0 O C:GLU292 4.4 80.3 1.0 O B:VAL9 4.4 80.3 1.0 N C:PRO297 4.4 80.3 1.0 CA C:PRO297 4.5 80.3 1.0 N B:ASP11 4.5 86.7 1.0 CB C:ASN296 4.5 80.3 1.0 CA B:ALA10 4.5 80.3 1.0 OD1 C:ASP301 4.5 83.9 1.0 CA B:ASP11 4.5 86.7 1.0 CG C:GLN293 4.5 80.3 1.0 N C:LEU294 4.6 80.3 1.0 CB C:ASP304 4.6 80.3 1.0 N C:GLY299 4.7 80.3 1.0 CA C:GLY299 4.9 80.3 1.0 CB C:GLN293 4.9 80.3 1.0 CA C:LEU294 5.0 80.3 1.0 C B:ASP11 5.0 86.7 1.0

Calcium binding site 4 out of 5 in the BEST1 in A Calcium-Bound Inactivated State


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 4 of BEST1 in A Calcium-Bound Inactivated State within 5.0Å range: probe atom residue distance (Å) B Occ D:Ca501 b:80.3 occ:1.00 OD2 D:ASP301 2.5 82.4 1.0 O C:ALA10 2.5 80.3 1.0 O D:ASN296 2.5 80.3 1.0 OD2 D:ASP304 2.6 80.3 1.0 O D:GLN293 2.7 80.3 1.0 OD1 D:ASP304 2.7 80.3 1.0 CG D:ASP304 3.0 80.3 1.0 CG D:ASP301 3.5 82.4 1.0 C C:ALA10 3.6 80.3 1.0 C D:ASN296 3.6 80.3 1.0 C D:GLN293 3.7 80.3 1.0 CB D:ASP301 4.1 82.4 1.0 CA D:GLN293 4.1 80.3 1.0 O C:VAL9 4.4 80.3 1.0 OD1 D:ASP301 4.4 82.4 1.0 N D:ASN296 4.4 80.3 1.0 CA D:ASN296 4.5 80.3 1.0 O D:GLU292 4.5 80.3 1.0 N C:ASP11 4.5 85.5 1.0 CA C:ALA10 4.5 80.3 1.0 N D:PRO297 4.5 80.3 1.0 CB D:ASP304 4.5 80.3 1.0 CA C:ASP11 4.5 85.5 1.0 CA D:PRO297 4.5 80.3 1.0 CB D:ASN296 4.6 80.3 1.0 N D:GLY299 4.6 80.3 1.0 CG D:GLN293 4.6 80.3 1.0 CA D:GLY299 4.7 80.3 1.0 N D:LEU294 4.8 80.3 1.0 N D:ASP301 4.8 82.4 1.0 CB D:GLN293 5.0 80.3 1.0 C C:ASP11 5.0 85.5 1.0

Calcium binding site 5 out of 5 in the BEST1 in A Calcium-Bound Inactivated State


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 5 of BEST1 in A Calcium-Bound Inactivated State within 5.0Å range: probe atom residue distance (Å) B Occ E:Ca501 b:80.3 occ:1.00 O E:GLN293 2.5 80.3 1.0 O E:ASN296 2.5 80.3 1.0 O D:ALA10 2.5 80.3 1.0 OD2 E:ASP301 2.5 83.0 1.0 OD1 E:ASP304 2.6 80.3 1.0 OD2 E:ASP304 2.7 80.3 1.0 CG E:ASP304 3.0 80.3 1.0 C E:GLN293 3.5 80.3 1.0 CG E:ASP301 3.6 83.0 1.0 C E:ASN296 3.6 80.3 1.0 C D:ALA10 3.6 80.3 1.0 CA E:GLN293 4.0 80.3 1.0 CB E:ASP301 4.1 83.0 1.0 N E:ASN296 4.4 80.3 1.0 O D:VAL9 4.4 80.3 1.0 CA E:ASN296 4.4 80.3 1.0 N E:PRO297 4.4 80.3 1.0 CA E:PRO297 4.4 80.3 1.0 O E:GLU292 4.4 80.3 1.0 CG E:GLN293 4.5 80.3 1.0 CB E:ASP304 4.5 80.3 1.0 N D:ASP11 4.5 84.8 1.0 OD1 E:ASP301 4.5 83.0 1.0 CA D:ALA10 4.5 80.3 1.0 CA D:ASP11 4.5 84.8 1.0 N E:LEU294 4.6 80.3 1.0 CB E:ASN296 4.6 80.3 1.0 N E:GLY299 4.7 80.3 1.0 CB E:GLN293 4.9 80.3 1.0 CA E:GLY299 4.9 80.3 1.0 N E:ASP301 4.9 83.0 1.0 CA E:LEU294 5.0 80.3 1.0 C D:ASP11 5.0 84.8 1.0

A.N.Miller, G.Vaisey, S.B.Long. Molecular Mechanisms of Gating in the Calcium-Activated Chloride Channel Bestrophin. Elife V. 8 2019.
ISSN: ESSN 2050-084X
PubMed: 30628889
DOI: 10.7554/ELIFE.43231