Calcium in PDB 6n25: BEST1 Open State W287F Mutant, Calcium-Bound
Calcium Binding Sites:
The binding sites of Calcium atom in the BEST1 Open State W287F Mutant, Calcium-Bound
(pdb code 6n25). This binding sites where shown within
5.0 Angstroms radius around Calcium atom.
In total 5 binding sites of Calcium where determined in the
BEST1 Open State W287F Mutant, Calcium-Bound, PDB code: 6n25:
Jump to Calcium binding site number:
1;
2;
3;
4;
5;
Calcium binding site 1 out
of 5 in 6n25
Go back to
Calcium Binding Sites List in 6n25
Calcium binding site 1 out
of 5 in the BEST1 Open State W287F Mutant, Calcium-Bound
 Mono view
 Stereo pair view
|
|
A full contact list of Calcium with other atoms in the Ca binding
site number 1 of BEST1 Open State W287F Mutant, Calcium-Bound within 5.0Å range:
|
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
A:Ca401
b:43.0
occ:1.00
|
O
|
A:ASN296
|
2.5
|
43.8
|
1.0
|
|
O
|
A:GLN293
|
2.5
|
49.1
|
1.0
|
|
O
|
E:ALA10
|
2.5
|
51.3
|
1.0
|
|
OD2
|
A:ASP301
|
2.6
|
52.9
|
1.0
|
|
OD2
|
A:ASP304
|
2.6
|
47.8
|
1.0
|
|
OD1
|
A:ASP304
|
2.8
|
47.8
|
1.0
|
|
CG
|
A:ASP304
|
3.0
|
47.8
|
1.0
|
|
C
|
A:GLN293
|
3.6
|
49.1
|
1.0
|
|
CG
|
A:ASP301
|
3.6
|
52.9
|
1.0
|
|
C
|
E:ALA10
|
3.6
|
51.3
|
1.0
|
|
C
|
A:ASN296
|
3.6
|
43.8
|
1.0
|
|
CA
|
A:GLN293
|
4.0
|
49.1
|
1.0
|
|
CB
|
A:ASP301
|
4.2
|
52.9
|
1.0
|
|
O
|
E:VAL9
|
4.4
|
50.8
|
1.0
|
|
N
|
E:ASP11
|
4.5
|
57.3
|
1.0
|
|
CA
|
A:PRO297
|
4.5
|
41.6
|
1.0
|
|
O
|
A:GLU292
|
4.5
|
52.2
|
1.0
|
|
CA
|
E:ASP11
|
4.5
|
57.3
|
1.0
|
|
N
|
A:PRO297
|
4.5
|
41.6
|
1.0
|
|
OD1
|
A:ASP301
|
4.5
|
52.9
|
1.0
|
|
CG
|
A:GLN293
|
4.5
|
49.1
|
1.0
|
|
CA
|
A:ASN296
|
4.5
|
43.8
|
1.0
|
|
CA
|
E:ALA10
|
4.5
|
51.3
|
1.0
|
|
N
|
A:GLY299
|
4.5
|
47.3
|
1.0
|
|
N
|
A:ASN296
|
4.5
|
43.8
|
1.0
|
|
CB
|
A:ASP304
|
4.5
|
47.8
|
1.0
|
|
CA
|
A:GLY299
|
4.6
|
47.3
|
1.0
|
|
CB
|
A:ASN296
|
4.6
|
43.8
|
1.0
|
|
N
|
A:LEU294
|
4.7
|
42.8
|
1.0
|
|
CB
|
A:GLN293
|
4.8
|
49.1
|
1.0
|
|
N
|
A:ASP301
|
4.9
|
52.9
|
1.0
|
|
C
|
E:ASP11
|
4.9
|
57.3
|
1.0
|
|
C
|
A:PRO297
|
5.0
|
41.6
|
1.0
|
|
Calcium binding site 2 out
of 5 in 6n25
Go back to
Calcium Binding Sites List in 6n25
Calcium binding site 2 out
of 5 in the BEST1 Open State W287F Mutant, Calcium-Bound
 Mono view
 Stereo pair view
|
|
A full contact list of Calcium with other atoms in the Ca binding
site number 2 of BEST1 Open State W287F Mutant, Calcium-Bound within 5.0Å range:
|
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
B:Ca401
b:45.6
occ:1.00
|
O
|
B:GLN293
|
2.4
|
49.5
|
1.0
|
|
O
|
A:ALA10
|
2.5
|
50.4
|
1.0
|
|
O
|
B:ASN296
|
2.5
|
44.2
|
1.0
|
|
OD2
|
B:ASP304
|
2.5
|
47.8
|
1.0
|
|
OD2
|
B:ASP301
|
2.6
|
53.4
|
1.0
|
|
OD1
|
B:ASP304
|
2.6
|
47.8
|
1.0
|
|
CG
|
B:ASP304
|
2.9
|
47.8
|
1.0
|
|
C
|
B:GLN293
|
3.5
|
49.5
|
1.0
|
|
CG
|
B:ASP301
|
3.6
|
53.4
|
1.0
|
|
C
|
A:ALA10
|
3.6
|
50.4
|
1.0
|
|
C
|
B:ASN296
|
3.6
|
44.2
|
1.0
|
|
CA
|
B:GLN293
|
4.0
|
49.5
|
1.0
|
|
CB
|
B:ASP301
|
4.1
|
53.4
|
1.0
|
|
CA
|
B:PRO297
|
4.4
|
41.9
|
1.0
|
|
CG
|
B:GLN293
|
4.4
|
49.5
|
1.0
|
|
CB
|
B:ASP304
|
4.4
|
47.8
|
1.0
|
|
N
|
A:ASP11
|
4.4
|
56.7
|
1.0
|
|
N
|
B:PRO297
|
4.4
|
41.9
|
1.0
|
|
CA
|
A:ASP11
|
4.4
|
56.7
|
1.0
|
|
CA
|
A:ALA10
|
4.5
|
50.4
|
1.0
|
|
OD1
|
B:ASP301
|
4.5
|
53.4
|
1.0
|
|
N
|
B:GLY299
|
4.5
|
46.9
|
1.0
|
|
O
|
A:VAL9
|
4.5
|
50.7
|
1.0
|
|
O
|
B:GLU292
|
4.5
|
52.8
|
1.0
|
|
CA
|
B:ASN296
|
4.5
|
44.2
|
1.0
|
|
N
|
B:ASN296
|
4.6
|
44.2
|
1.0
|
|
N
|
B:LEU294
|
4.7
|
43.1
|
1.0
|
|
CA
|
B:GLY299
|
4.7
|
46.9
|
1.0
|
|
CB
|
B:ASN296
|
4.7
|
44.2
|
1.0
|
|
CB
|
B:GLN293
|
4.8
|
49.5
|
1.0
|
|
N
|
B:ASP301
|
4.9
|
53.4
|
1.0
|
|
C
|
B:PRO297
|
4.9
|
41.9
|
1.0
|
|
C
|
A:ASP11
|
4.9
|
56.7
|
1.0
|
|
Calcium binding site 3 out
of 5 in 6n25
Go back to
Calcium Binding Sites List in 6n25
Calcium binding site 3 out
of 5 in the BEST1 Open State W287F Mutant, Calcium-Bound
 Mono view
 Stereo pair view
|
|
A full contact list of Calcium with other atoms in the Ca binding
site number 3 of BEST1 Open State W287F Mutant, Calcium-Bound within 5.0Å range:
|
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
C:Ca401
b:44.1
occ:1.00
|
O
|
C:GLN293
|
2.5
|
48.9
|
1.0
|
|
O
|
B:ALA10
|
2.5
|
50.7
|
1.0
|
|
O
|
C:ASN296
|
2.5
|
43.5
|
1.0
|
|
OD2
|
C:ASP304
|
2.5
|
48.1
|
1.0
|
|
OD2
|
C:ASP301
|
2.6
|
53.4
|
1.0
|
|
OD1
|
C:ASP304
|
2.7
|
48.1
|
1.0
|
|
CG
|
C:ASP304
|
2.9
|
48.1
|
1.0
|
|
C
|
C:GLN293
|
3.5
|
48.9
|
1.0
|
|
CG
|
C:ASP301
|
3.6
|
53.4
|
1.0
|
|
C
|
B:ALA10
|
3.6
|
50.7
|
1.0
|
|
C
|
C:ASN296
|
3.6
|
43.5
|
1.0
|
|
CA
|
C:GLN293
|
4.0
|
48.9
|
1.0
|
|
CB
|
C:ASP301
|
4.1
|
53.4
|
1.0
|
|
CA
|
C:PRO297
|
4.4
|
41.5
|
1.0
|
|
CG
|
C:GLN293
|
4.4
|
48.9
|
1.0
|
|
CB
|
C:ASP304
|
4.4
|
48.1
|
1.0
|
|
N
|
C:PRO297
|
4.4
|
41.5
|
1.0
|
|
N
|
B:ASP11
|
4.4
|
57.4
|
1.0
|
|
CA
|
B:ASP11
|
4.5
|
57.4
|
1.0
|
|
OD1
|
C:ASP301
|
4.5
|
53.4
|
1.0
|
|
CA
|
B:ALA10
|
4.5
|
50.7
|
1.0
|
|
N
|
C:GLY299
|
4.5
|
47.8
|
1.0
|
|
O
|
C:GLU292
|
4.5
|
52.6
|
1.0
|
|
O
|
B:VAL9
|
4.5
|
50.2
|
1.0
|
|
CA
|
C:ASN296
|
4.5
|
43.5
|
1.0
|
|
N
|
C:ASN296
|
4.6
|
43.5
|
1.0
|
|
CA
|
C:GLY299
|
4.7
|
47.8
|
1.0
|
|
N
|
C:LEU294
|
4.7
|
42.0
|
1.0
|
|
CB
|
C:ASN296
|
4.7
|
43.5
|
1.0
|
|
CB
|
C:GLN293
|
4.8
|
48.9
|
1.0
|
|
N
|
C:ASP301
|
4.9
|
53.4
|
1.0
|
|
C
|
C:PRO297
|
4.9
|
41.5
|
1.0
|
|
C
|
B:ASP11
|
4.9
|
57.4
|
1.0
|
|
Calcium binding site 4 out
of 5 in 6n25
Go back to
Calcium Binding Sites List in 6n25
Calcium binding site 4 out
of 5 in the BEST1 Open State W287F Mutant, Calcium-Bound
 Mono view
 Stereo pair view
|
|
A full contact list of Calcium with other atoms in the Ca binding
site number 4 of BEST1 Open State W287F Mutant, Calcium-Bound within 5.0Å range:
|
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
D:Ca401
b:44.3
occ:1.00
|
O
|
D:GLN293
|
2.5
|
48.3
|
1.0
|
|
O
|
C:ALA10
|
2.5
|
50.8
|
1.0
|
|
O
|
D:ASN296
|
2.5
|
43.6
|
1.0
|
|
OD2
|
D:ASP304
|
2.5
|
48.0
|
1.0
|
|
OD2
|
D:ASP301
|
2.6
|
53.2
|
1.0
|
|
OD1
|
D:ASP304
|
2.7
|
48.0
|
1.0
|
|
CG
|
D:ASP304
|
3.0
|
48.0
|
1.0
|
|
C
|
D:GLN293
|
3.5
|
48.3
|
1.0
|
|
CG
|
D:ASP301
|
3.6
|
53.2
|
1.0
|
|
C
|
C:ALA10
|
3.6
|
50.8
|
1.0
|
|
C
|
D:ASN296
|
3.6
|
43.6
|
1.0
|
|
CA
|
D:GLN293
|
4.0
|
48.3
|
1.0
|
|
CB
|
D:ASP301
|
4.1
|
53.2
|
1.0
|
|
CA
|
D:PRO297
|
4.4
|
41.6
|
1.0
|
|
CG
|
D:GLN293
|
4.4
|
48.3
|
1.0
|
|
N
|
C:ASP11
|
4.4
|
56.5
|
1.0
|
|
CA
|
C:ASP11
|
4.5
|
56.5
|
1.0
|
|
N
|
D:PRO297
|
4.5
|
41.6
|
1.0
|
|
CB
|
D:ASP304
|
4.5
|
48.0
|
1.0
|
|
OD1
|
D:ASP301
|
4.5
|
53.2
|
1.0
|
|
O
|
D:GLU292
|
4.5
|
51.8
|
1.0
|
|
CA
|
C:ALA10
|
4.5
|
50.8
|
1.0
|
|
O
|
C:VAL9
|
4.5
|
50.9
|
1.0
|
|
N
|
D:GLY299
|
4.5
|
47.0
|
1.0
|
|
CA
|
D:ASN296
|
4.5
|
43.6
|
1.0
|
|
N
|
D:ASN296
|
4.5
|
43.6
|
1.0
|
|
CA
|
D:GLY299
|
4.6
|
47.0
|
1.0
|
|
N
|
D:LEU294
|
4.7
|
42.0
|
1.0
|
|
CB
|
D:ASN296
|
4.7
|
43.6
|
1.0
|
|
CB
|
D:GLN293
|
4.8
|
48.3
|
1.0
|
|
N
|
D:ASP301
|
4.9
|
53.2
|
1.0
|
|
C
|
C:ASP11
|
4.9
|
56.5
|
1.0
|
|
C
|
D:PRO297
|
5.0
|
41.6
|
1.0
|
|
Calcium binding site 5 out
of 5 in 6n25
Go back to
Calcium Binding Sites List in 6n25
Calcium binding site 5 out
of 5 in the BEST1 Open State W287F Mutant, Calcium-Bound
 Mono view
 Stereo pair view
|
|
A full contact list of Calcium with other atoms in the Ca binding
site number 5 of BEST1 Open State W287F Mutant, Calcium-Bound within 5.0Å range:
|
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
E:Ca401
b:43.8
occ:1.00
|
O
|
E:ASN296
|
2.5
|
43.8
|
1.0
|
|
O
|
E:GLN293
|
2.5
|
48.9
|
1.0
|
|
O
|
D:ALA10
|
2.5
|
50.1
|
1.0
|
|
OD2
|
E:ASP301
|
2.6
|
53.2
|
1.0
|
|
OD2
|
E:ASP304
|
2.6
|
47.6
|
1.0
|
|
OD1
|
E:ASP304
|
2.8
|
47.6
|
1.0
|
|
CG
|
E:ASP304
|
3.1
|
47.6
|
1.0
|
|
C
|
E:GLN293
|
3.5
|
48.9
|
1.0
|
|
CG
|
E:ASP301
|
3.6
|
53.2
|
1.0
|
|
C
|
D:ALA10
|
3.6
|
50.1
|
1.0
|
|
C
|
E:ASN296
|
3.6
|
43.8
|
1.0
|
|
CA
|
E:GLN293
|
4.0
|
48.9
|
1.0
|
|
CB
|
E:ASP301
|
4.2
|
53.2
|
1.0
|
|
O
|
E:GLU292
|
4.4
|
51.6
|
1.0
|
|
N
|
D:ASP11
|
4.4
|
56.0
|
1.0
|
|
O
|
D:VAL9
|
4.5
|
50.0
|
1.0
|
|
CA
|
E:PRO297
|
4.5
|
41.5
|
1.0
|
|
CA
|
D:ASP11
|
4.5
|
56.0
|
1.0
|
|
N
|
E:PRO297
|
4.5
|
41.5
|
1.0
|
|
CG
|
E:GLN293
|
4.5
|
48.9
|
1.0
|
|
CA
|
E:ASN296
|
4.5
|
43.8
|
1.0
|
|
OD1
|
E:ASP301
|
4.5
|
53.2
|
1.0
|
|
CA
|
D:ALA10
|
4.5
|
50.1
|
1.0
|
|
N
|
E:ASN296
|
4.5
|
43.8
|
1.0
|
|
N
|
E:GLY299
|
4.5
|
46.8
|
1.0
|
|
CB
|
E:ASP304
|
4.6
|
47.6
|
1.0
|
|
CB
|
E:ASN296
|
4.6
|
43.8
|
1.0
|
|
CA
|
E:GLY299
|
4.7
|
46.8
|
1.0
|
|
N
|
E:LEU294
|
4.7
|
42.4
|
1.0
|
|
CB
|
E:GLN293
|
4.8
|
48.9
|
1.0
|
|
C
|
D:ASP11
|
4.9
|
56.0
|
1.0
|
|
N
|
E:ASP301
|
4.9
|
53.2
|
1.0
|
|
C
|
E:PRO297
|
5.0
|
41.5
|
1.0
|
|
Reference:
A.N.Miller,
G.Vaisey,
S.B.Long.
Molecular Mechanisms of Gating in the Calcium-Activated Chloride Channel Bestrophin. Elife V. 8 2019.
ISSN: ESSN 2050-084X
PubMed: 30628889
DOI: 10.7554/ELIFE.43231
Page generated: Sat Dec 12 07:20:35 2020
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