Atomistry » Calcium » PDB 6r65-6ry2 » 6rjb
Atomistry »
  Calcium »
    PDB 6r65-6ry2 »
      6rjb »

Calcium in PDB 6rjb: Human Transketolase Variant T382E

Enzymatic activity of Human Transketolase Variant T382E

All present enzymatic activity of Human Transketolase Variant T382E:
2.2.1.1;

Protein crystallography data

The structure of Human Transketolase Variant T382E, PDB code: 6rjb was solved by F.Rabe Von Pappenheim, K.Tittmann, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 72.81 / 1.15
Space group P 1 21 1
Cell size a, b, c (Å), α, β, γ (°) 73.000, 85.780, 92.790, 90.00, 94.15, 90.00
R / Rfree (%) 12.3 / 14.8

Other elements in 6rjb:

The structure of Human Transketolase Variant T382E also contains other interesting chemical elements:

Magnesium (Mg) 2 atoms
Sodium (Na) 2 atoms

Calcium Binding Sites:

The binding sites of Calcium atom in the Human Transketolase Variant T382E (pdb code 6rjb). This binding sites where shown within 5.0 Angstroms radius around Calcium atom.
In total 2 binding sites of Calcium where determined in the Human Transketolase Variant T382E, PDB code: 6rjb:
Jump to Calcium binding site number: 1; 2;

Calcium binding site 1 out of 2 in 6rjb

Go back to Calcium Binding Sites List in 6rjb
Calcium binding site 1 out of 2 in the Human Transketolase Variant T382E


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 1 of Human Transketolase Variant T382E within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Ca703

b:10.2
occ:0.22
MG A:MG702 0.3 11.0 0.8
OD1 A:ASN185 2.0 11.2 1.0
OD1 A:ASP155 2.0 10.2 1.0
O A:HOH964 2.1 11.0 1.0
O21 A:TDP701 2.1 10.5 1.0
O12 A:TDP701 2.2 9.9 1.0
O A:LEU187 2.2 11.4 1.0
CG A:ASN185 2.9 10.9 1.0
HD21 A:ASN185 3.0 13.5 1.0
H A:ASP155 3.1 12.2 1.0
CG A:ASP155 3.2 10.7 1.0
P2 A:TDP701 3.3 9.9 1.0
ND2 A:ASN185 3.3 11.2 1.0
C A:LEU187 3.4 11.5 1.0
H A:GLY156 3.4 12.3 1.0
P1 A:TDP701 3.4 10.2 1.0
H A:LEU187 3.4 12.9 1.0
O11 A:TDP701 3.5 10.1 1.0
HZ2 A:LYS244 3.5 13.3 1.0
H A:ASN185 3.7 12.5 1.0
O22 A:TDP701 3.7 11.2 1.0
HA2 A:GLY188 3.8 12.2 1.0
OD2 A:ASP155 3.8 12.2 1.0
HD2 A:LYS244 3.8 14.1 1.0
N A:ASP155 3.9 10.1 1.0
N A:LEU187 4.0 10.8 1.0
HD22 A:ASN185 4.1 13.5 1.0
O A:ASP183 4.2 10.7 1.0
N A:GLY156 4.2 10.2 1.0
CA A:LEU187 4.3 10.8 1.0
CB A:ASN185 4.3 11.2 1.0
O5G A:TDP701 4.3 11.1 1.0
N A:GLY188 4.3 10.5 1.0
CB A:ASP155 4.3 10.2 1.0
N A:ASN185 4.4 10.4 1.0
NZ A:LYS244 4.4 11.1 1.0
HB2 A:LEU187 4.5 14.3 1.0
CA A:ASP155 4.5 10.2 1.0
O13 A:TDP701 4.5 10.7 1.0
CA A:GLY188 4.5 10.2 1.0
C A:ASN185 4.5 11.0 1.0
H A:ARG186 4.5 13.3 1.0
O23 A:TDP701 4.6 10.5 1.0
CA A:ASN185 4.6 10.4 1.0
N A:ARG186 4.6 11.1 1.0
HA3 A:GLY154 4.6 12.2 1.0
HB2 A:ALA193 4.6 15.7 1.0
HA2 A:GLY154 4.7 12.2 1.0
HB3 A:ASP155 4.7 12.3 1.0
HB3 A:ASN185 4.7 13.4 1.0
CD A:LYS244 4.7 11.7 1.0
HZ1 A:LYS244 4.8 13.3 1.0
HB2 A:ASN185 4.9 13.4 1.0
C A:ASP155 4.9 10.2 1.0
HZ3 A:LYS244 4.9 13.3 1.0
C A:GLY154 4.9 10.4 1.0
C A:ARG186 4.9 11.4 1.0
CB A:LEU187 5.0 11.9 1.0
O A:ASN185 5.0 11.4 1.0
HE3 A:LYS244 5.0 13.5 1.0
CA A:GLY154 5.0 10.2 1.0
HA3 A:GLY156 5.0 12.7 1.0

Calcium binding site 2 out of 2 in 6rjb

Go back to Calcium Binding Sites List in 6rjb
Calcium binding site 2 out of 2 in the Human Transketolase Variant T382E


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 2 of Human Transketolase Variant T382E within 5.0Å range:
probe atom residue distance (Å) B Occ
B:Ca703

b:10.2
occ:0.26
MG B:MG702 0.3 10.7 0.7
O23 B:TDP701 1.9 10.4 1.0
O13 B:TDP701 2.1 10.3 1.0
O B:HOH948 2.1 10.8 1.0
OD1 B:ASP155 2.1 10.7 1.0
OD1 B:ASN185 2.1 11.2 1.0
O B:LEU187 2.2 10.7 1.0
HD21 B:ASN185 3.0 13.1 1.0
CG B:ASN185 3.0 10.9 1.0
P2 B:TDP701 3.1 10.2 1.0
H B:ASP155 3.1 12.3 1.0
P1 B:TDP701 3.2 10.0 1.0
O11 B:TDP701 3.3 10.2 1.0
CG B:ASP155 3.3 10.6 1.0
ND2 B:ASN185 3.3 10.9 1.0
H B:GLY156 3.4 12.1 1.0
C B:LEU187 3.4 10.2 1.0
HZ2 B:LYS244 3.4 12.4 1.0
O21 B:TDP701 3.5 11.7 1.0
H B:LEU187 3.6 12.3 1.0
HA2 B:GLY188 3.7 12.1 1.0
HD2 B:LYS244 3.8 13.3 1.0
H B:ASN185 3.9 12.3 1.0
N B:ASP155 3.9 10.2 1.0
OD2 B:ASP155 4.0 11.4 1.0
O5G B:TDP701 4.1 10.8 1.0
N B:LEU187 4.1 10.3 1.0
HD22 B:ASN185 4.2 13.1 1.0
N B:GLY156 4.2 10.1 1.0
N B:GLY188 4.3 10.6 1.0
NZ B:LYS244 4.3 10.4 1.0
O12 B:TDP701 4.3 10.8 1.0
O B:ASP183 4.3 11.0 1.0
CA B:LEU187 4.3 10.1 1.0
O22 B:TDP701 4.3 10.6 1.0
CA B:GLY188 4.4 10.1 1.0
CB B:ASN185 4.4 10.9 1.0
CB B:ASP155 4.5 10.2 1.0
HA3 B:GLY154 4.5 12.9 1.0
CA B:ASP155 4.5 10.6 1.0
HB2 B:LEU187 4.5 13.4 1.0
N B:ASN185 4.6 10.3 1.0
HA2 B:GLY154 4.6 12.9 1.0
HZ3 B:LYS244 4.7 12.4 1.0
HZ1 B:LYS244 4.7 12.4 1.0
CD B:LYS244 4.7 11.1 1.0
C B:ASN185 4.7 10.0 1.0
H B:ARG186 4.8 12.7 1.0
HB2 B:ALA193 4.8 14.4 1.0
CA B:ASN185 4.8 10.4 1.0
N B:ARG186 4.9 10.6 1.0
HB3 B:ASP155 4.9 12.3 1.0
HB3 B:ASN185 4.9 13.1 1.0
HE3 B:LYS244 4.9 13.6 1.0
C B:ASP155 4.9 10.1 1.0
CE B:LYS244 4.9 11.3 1.0
C B:GLY154 4.9 10.8 1.0
CA B:GLY154 4.9 10.7 1.0
HA3 B:GLY156 4.9 11.8 1.0
HB2 B:ASN185 5.0 13.1 1.0

Reference:

S.Dai, L.M.Funk, F.R.Von Pappenheim, V.Sautner, M.Paulikat, B.Schroder, J.Uranga, R.A.Mata, K.Tittmann. Low-Barrier Hydrogen Bonds in Enzyme Cooperativity. Nature V. 573 609 2019.
ISSN: ESSN 1476-4687
PubMed: 31534226
DOI: 10.1038/S41586-019-1581-9
Page generated: Tue Jul 16 14:22:43 2024

Last articles

Zn in 9JPJ
Zn in 9JP7
Zn in 9JPK
Zn in 9JPL
Zn in 9GN6
Zn in 9GN7
Zn in 9GKU
Zn in 9GKW
Zn in 9GKX
Zn in 9GL0
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy