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Atomistry » Calcium » PDB 6ry5-6sau » 6s7f » |
Calcium in PDB 6s7f: Human CD73 (5'-Nucleotidase) in Complex with PSB12379 (An Aopcp Derivative) in the Closed StateEnzymatic activity of Human CD73 (5'-Nucleotidase) in Complex with PSB12379 (An Aopcp Derivative) in the Closed State
All present enzymatic activity of Human CD73 (5'-Nucleotidase) in Complex with PSB12379 (An Aopcp Derivative) in the Closed State:
3.1.3.5; Protein crystallography data
The structure of Human CD73 (5'-Nucleotidase) in Complex with PSB12379 (An Aopcp Derivative) in the Closed State, PDB code: 6s7f
was solved by
J.Pippel,
N.Strater,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 6s7f:
The structure of Human CD73 (5'-Nucleotidase) in Complex with PSB12379 (An Aopcp Derivative) in the Closed State also contains other interesting chemical elements:
Calcium Binding Sites:
The binding sites of Calcium atom in the Human CD73 (5'-Nucleotidase) in Complex with PSB12379 (An Aopcp Derivative) in the Closed State
(pdb code 6s7f). This binding sites where shown within
5.0 Angstroms radius around Calcium atom.
In total only one binding site of Calcium was determined in the Human CD73 (5'-Nucleotidase) in Complex with PSB12379 (An Aopcp Derivative) in the Closed State, PDB code: 6s7f: Calcium binding site 1 out of 1 in 6s7fGo back to Calcium Binding Sites List in 6s7f
Calcium binding site 1 out
of 1 in the Human CD73 (5'-Nucleotidase) in Complex with PSB12379 (An Aopcp Derivative) in the Closed State
Mono view Stereo pair view
Reference:
S.Bhattarai,
J.Pippel,
A.Meyer,
M.Freundlieb,
C.Schmies,
A.Abdelrahman,
A.Fiene,
S.Y.Lee,
H.Zimmermann,
A.El-Tayeb,
G.G.Yegutkin,
N.Strater,
C.E.Muller.
X-Ray Co-Crystal Structure Guides the Way to Subnanomolar Competitive Ecto-5'-Nucleotidase (CD73) Inhibitors For Cancer Immunotherapy Adv Ther 2019.
Page generated: Tue Jul 16 14:34:11 2024
DOI: 10.1002/ADTP.201900075 |
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