Calcium in PDB 6v4n: Structure of Human 1G05 Fab in Complex with Influenza Virus Neuraminidase From B/Phuket/3073/2013

Enzymatic activity of Structure of Human 1G05 Fab in Complex with Influenza Virus Neuraminidase From B/Phuket/3073/2013

All present enzymatic activity of Structure of Human 1G05 Fab in Complex with Influenza Virus Neuraminidase From B/Phuket/3073/2013:
3.2.1.18;

Calcium Binding Sites:

The binding sites of Calcium atom in the Structure of Human 1G05 Fab in Complex with Influenza Virus Neuraminidase From B/Phuket/3073/2013 (pdb code 6v4n). This binding sites where shown within 5.0 Angstroms radius around Calcium atom.
In total 4 binding sites of Calcium where determined in the Structure of Human 1G05 Fab in Complex with Influenza Virus Neuraminidase From B/Phuket/3073/2013, PDB code: 6v4n:
Jump to Calcium binding site number: 1; 2; 3; 4;

Calcium binding site 1 out of 4 in 6v4n

Go back to Calcium Binding Sites List in 6v4n
Calcium binding site 1 out of 4 in the Structure of Human 1G05 Fab in Complex with Influenza Virus Neuraminidase From B/Phuket/3073/2013


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 1 of Structure of Human 1G05 Fab in Complex with Influenza Virus Neuraminidase From B/Phuket/3073/2013 within 5.0Å range:
probe atom residue distance (Å) B Occ
I:Ca509

b:45.3
occ:1.00
 O I:ASP293 2.2 45.1 1.0
O I:HOH618 2.2 44.3 1.0
O I:GLY346 2.3 43.8 1.0
O I:THR297 2.3 46.7 1.0
O I:GLY344 2.4 47.6 1.0
OD2 I:ASP324 3.0 43.6 1.0
C I:ASP293 3.4 45.1 1.0
C I:THR297 3.4 46.7 1.0
C I:GLY344 3.5 47.6 1.0
C I:GLY346 3.5 43.8 1.0
CG I:ASP324 3.9 43.6 1.0
CA I:GLY344 4.0 47.6 1.0
CA I:ALA298 4.1 46.1 1.0
CA I:ASN294 4.1 45.1 1.0
N I:ALA298 4.1 46.1 1.0
N I:ASN294 4.2 45.1 1.0
CA I:GLY347 4.2 42.4 1.0
N I:GLY347 4.3 42.4 1.0
N I:THR297 4.4 46.7 1.0
N I:GLY346 4.4 43.8 1.0
CA I:ASP293 4.5 45.1 1.0
C I:ASN294 4.5 45.1 1.0
CB I:ASP324 4.5 43.6 1.0
CA I:THR297 4.5 46.7 1.0
CA I:GLY346 4.6 43.8 1.0
C I:SER345 4.6 46.6 1.0
N I:SER345 4.6 46.6 1.0
N I:SER295 4.6 46.6 1.0
OD1 I:ASP324 4.6 43.6 1.0
CB I:ASP293 4.7 45.1 1.0
N I:ASP293 4.7 45.1 1.0
CA I:SER345 4.9 46.6 1.0
O I:PRO326 4.9 44.5 1.0
C I:ALA298 4.9 46.1 1.0
O I:SER345 5.0 46.6 1.0

Calcium binding site 2 out of 4 in 6v4n

Go back to Calcium Binding Sites List in 6v4n
Calcium binding site 2 out of 4 in the Structure of Human 1G05 Fab in Complex with Influenza Virus Neuraminidase From B/Phuket/3073/2013


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 2 of Structure of Human 1G05 Fab in Complex with Influenza Virus Neuraminidase From B/Phuket/3073/2013 within 5.0Å range:
probe atom residue distance (Å) B Occ
M:Ca509

b:46.7
occ:1.00
 O M:ASP293 2.2 45.2 1.0
O M:HOH621 2.2 44.7 1.0
O M:GLY346 2.3 44.4 1.0
O M:THR297 2.3 47.2 1.0
O M:GLY344 2.4 48.3 1.0
OD2 M:ASP324 3.0 43.9 1.0
C M:ASP293 3.4 45.2 1.0
C M:THR297 3.4 47.2 1.0
C M:GLY344 3.5 48.3 1.0
C M:GLY346 3.5 44.4 1.0
CG M:ASP324 3.9 43.9 1.0
CA M:GLY344 4.0 48.3 1.0
CA M:ALA298 4.1 46.5 1.0
CA M:ASN294 4.1 45.3 1.0
N M:ALA298 4.1 46.5 1.0
N M:ASN294 4.2 45.3 1.0
CA M:GLY347 4.2 42.6 1.0
N M:GLY347 4.3 42.6 1.0
N M:GLY346 4.4 44.4 1.0
N M:THR297 4.4 47.2 1.0
CA M:ASP293 4.5 45.2 1.0
C M:ASN294 4.5 45.3 1.0
CB M:ASP324 4.5 43.9 1.0
CA M:THR297 4.5 47.2 1.0
CA M:GLY346 4.6 44.4 1.0
C M:SER345 4.6 47.6 1.0
N M:SER345 4.6 47.6 1.0
N M:SER295 4.6 46.8 1.0
OD1 M:ASP324 4.6 43.9 1.0
CB M:ASP293 4.7 45.2 1.0
N M:ASP293 4.7 45.2 1.0
CA M:SER345 4.9 47.6 1.0
C M:ALA298 4.9 46.5 1.0
O M:PRO326 4.9 45.1 1.0
O M:SER345 4.9 47.6 1.0

Calcium binding site 3 out of 4 in 6v4n

Go back to Calcium Binding Sites List in 6v4n
Calcium binding site 3 out of 4 in the Structure of Human 1G05 Fab in Complex with Influenza Virus Neuraminidase From B/Phuket/3073/2013


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 3 of Structure of Human 1G05 Fab in Complex with Influenza Virus Neuraminidase From B/Phuket/3073/2013 within 5.0Å range:
probe atom residue distance (Å) B Occ
N:Ca509

b:45.7
occ:1.00
 O N:ASP293 2.2 45.2 1.0
O N:HOH623 2.2 44.3 1.0
O N:GLY346 2.3 44.0 1.0
O N:THR297 2.3 46.8 1.0
O N:GLY344 2.4 47.8 1.0
OD2 N:ASP324 3.0 43.8 1.0
C N:ASP293 3.4 45.2 1.0
C N:THR297 3.4 46.8 1.0
C N:GLY344 3.5 47.8 1.0
C N:GLY346 3.5 44.0 1.0
CG N:ASP324 3.9 43.8 1.0
CA N:GLY344 4.0 47.8 1.0
CA N:ALA298 4.1 46.1 1.0
CA N:ASN294 4.1 45.2 1.0
N N:ALA298 4.1 46.1 1.0
N N:ASN294 4.2 45.2 1.0
CA N:GLY347 4.2 42.5 1.0
N N:GLY347 4.3 42.5 1.0
N N:THR297 4.4 46.8 1.0
N N:GLY346 4.4 44.0 1.0
C N:ASN294 4.5 45.2 1.0
CA N:ASP293 4.5 45.2 1.0
CB N:ASP324 4.5 43.8 1.0
CA N:THR297 4.5 46.8 1.0
CA N:GLY346 4.6 44.0 1.0
C N:SER345 4.6 47.0 1.0
N N:SER345 4.6 47.0 1.0
OD1 N:ASP324 4.6 43.8 1.0
N N:SER295 4.6 46.7 1.0
N N:ASP293 4.7 45.2 1.0
CB N:ASP293 4.7 45.2 1.0
CA N:SER345 4.9 47.0 1.0
C N:ALA298 4.9 46.1 1.0
O N:PRO326 4.9 44.9 1.0
O N:SER345 5.0 47.0 1.0

Calcium binding site 4 out of 4 in 6v4n

Go back to Calcium Binding Sites List in 6v4n
Calcium binding site 4 out of 4 in the Structure of Human 1G05 Fab in Complex with Influenza Virus Neuraminidase From B/Phuket/3073/2013


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 4 of Structure of Human 1G05 Fab in Complex with Influenza Virus Neuraminidase From B/Phuket/3073/2013 within 5.0Å range:
probe atom residue distance (Å) B Occ
W:Ca509

b:45.6
occ:1.00
 O W:ASP293 2.2 44.9 1.0
O W:HOH615 2.2 44.5 1.0
O W:GLY346 2.3 43.7 1.0
O W:THR297 2.3 46.6 1.0
O W:GLY344 2.4 47.8 1.0
OD2 W:ASP324 3.0 43.5 1.0
C W:ASP293 3.4 44.9 1.0
C W:THR297 3.4 46.6 1.0
C W:GLY344 3.5 47.8 1.0
C W:GLY346 3.5 43.7 1.0
CG W:ASP324 3.9 43.5 1.0
CA W:GLY344 4.0 47.8 1.0
CA W:ALA298 4.1 46.0 1.0
CA W:ASN294 4.1 44.8 1.0
N W:ALA298 4.1 46.0 1.0
N W:ASN294 4.2 44.8 1.0
CA W:GLY347 4.2 42.1 1.0
N W:GLY347 4.3 42.1 1.0
N W:THR297 4.4 46.6 1.0
N W:GLY346 4.4 43.7 1.0
CA W:ASP293 4.5 44.9 1.0
C W:ASN294 4.5 44.8 1.0
CB W:ASP324 4.5 43.5 1.0
CA W:THR297 4.5 46.6 1.0
CA W:GLY346 4.6 43.7 1.0
C W:SER345 4.6 47.1 1.0
N W:SER345 4.6 47.1 1.0
OD1 W:ASP324 4.6 43.5 1.0
N W:SER295 4.6 46.6 1.0
CB W:ASP293 4.7 44.9 1.0
N W:ASP293 4.7 44.9 1.0
CA W:SER345 4.9 47.1 1.0
C W:ALA298 4.9 46.0 1.0
O W:PRO326 4.9 44.6 1.0
O W:SER345 4.9 47.1 1.0

Reference:

A.Madsen, Y.N.Dai, M.Mcmahon, A.J.Schmitz, J.S.Turner, J.Tan, T.Lei, W.B.Alsoussi, S.Strohmeier, M.Amor, B.M.Mohammed, P.A.Mudd, V.Simon, R.J.Cox, D.H.Fremont, F.Krammer, A.H.Ellebedy. Human Antibodies Targeting Influenza B Virus Neuraminidase Active Site Are Broadly Protective. Immunity V. 53 852 2020.
ISSN: ISSN 1074-7613
PubMed: 32976769
DOI: 10.1016/J.IMMUNI.2020.08.015
Page generated: Sat Dec 12 07:48:43 2020

Last articles

Zn in 8WB0
Zn in 8WAX
Zn in 8WAU
Zn in 8WAZ
Zn in 8WAY
Zn in 8WAV
Zn in 8WAW
Zn in 8WAT
Zn in 8W7M
Zn in 8WD3
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy