Calcium in PDB 6v5b: Human Drosha and DGCR8 in Complex with Primary Microrna (Mp/Rna Complex) - Active State

Enzymatic activity of Human Drosha and DGCR8 in Complex with Primary Microrna (Mp/Rna Complex) - Active State

All present enzymatic activity of Human Drosha and DGCR8 in Complex with Primary Microrna (Mp/Rna Complex) - Active State:
3.1.26.3;

Other elements in 6v5b:

The structure of Human Drosha and DGCR8 in Complex with Primary Microrna (Mp/Rna Complex) - Active State also contains other interesting chemical elements:

Zinc (Zn) 2 atoms

Calcium Binding Sites:

The binding sites of Calcium atom in the Human Drosha and DGCR8 in Complex with Primary Microrna (Mp/Rna Complex) - Active State (pdb code 6v5b). This binding sites where shown within 5.0 Angstroms radius around Calcium atom.
In total only one binding site of Calcium was determined in the Human Drosha and DGCR8 in Complex with Primary Microrna (Mp/Rna Complex) - Active State, PDB code: 6v5b:

Calcium binding site 1 out of 1 in 6v5b

Go back to Calcium Binding Sites List in 6v5b
Calcium binding site 1 out of 1 in the Human Drosha and DGCR8 in Complex with Primary Microrna (Mp/Rna Complex) - Active State


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 1 of Human Drosha and DGCR8 in Complex with Primary Microrna (Mp/Rna Complex) - Active State within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Ca1403

b:0.7
occ:1.00
OD1 A:ASP1151 2.3 0.2 1.0
OP1 D:U21 2.7 0.9 1.0
OE2 A:GLU1222 2.8 0.2 1.0
CG A:ASP1151 3.3 0.2 1.0
NE2 A:GLN1187 3.4 0.3 1.0
OD1 A:ASN1184 3.5 0.4 1.0
OD1 A:ASP1219 3.5 0.2 1.0
CD A:GLU1222 3.6 0.2 1.0
CG A:GLU1222 3.8 0.2 1.0
P D:U21 3.9 0.9 1.0
CB A:ASP1151 4.0 0.2 1.0
OD2 A:ASP1151 4.1 0.2 1.0
O3' D:C20 4.1 0.4 1.0
OE1 A:GLU1222 4.6 0.2 1.0
CD A:GLN1187 4.7 0.3 1.0
CG A:ASN1184 4.7 0.4 1.0
CG A:ASP1219 4.8 0.2 1.0
O A:ASN1183 4.8 0.7 1.0
C5' D:U21 4.8 0.9 1.0
CA A:ASP1151 4.9 0.2 1.0
O5' D:U21 4.9 0.9 1.0
OP2 D:U21 5.0 0.9 1.0
OE1 A:GLU1147 5.0 0.8 1.0

Reference:

A.C.Partin, K.Zhang, B.C.Jeong, E.Herrell, S.Li, W.Chiu, Y.Nam. Cryo-Em Structures of Human Drosha and DGCR8 in Complex with Primary Microrna. Mol.Cell 2020.
ISSN: ISSN 1097-2765
PubMed: 32220646
DOI: 10.1016/J.MOLCEL.2020.02.016
Page generated: Sat Dec 12 07:49:04 2020

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