Calcium in PDB 6vel: Crystal Structure of Human E-Cadherin Bound By Mouse Monoclonal Antibody 66E8FAB

The structure of Crystal Structure of Human E-Cadherin Bound By Mouse Monoclonal Antibody 66E8FAB, PDB code: 6vel was solved by Seattle Structural Genomics Center For Infectious Disease, Seattlestructural Genomics Center For Infectious Disease (Ssgcid), with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	46.54 / 2.65
Space group	P 31 2 1
Cell size a, b, c (Å), α, β, γ (°)	142.170, 142.170, 90.320, 90.00, 90.00, 120.00
R / Rfree (%)	18.3 / 23.3

The structure of Crystal Structure of Human E-Cadherin Bound By Mouse Monoclonal Antibody 66E8FAB also contains other interesting chemical elements:

Sodium

(Na)

1 atom

The binding sites of Calcium atom in the Crystal Structure of Human E-Cadherin Bound By Mouse Monoclonal Antibody 66E8FAB (pdb code 6vel). This binding sites where shown within 5.0 Angstroms radius around Calcium atom.
In total 2 binding sites of Calcium where determined in the Crystal Structure of Human E-Cadherin Bound By Mouse Monoclonal Antibody 66E8FAB, PDB code: 6vel:
Jump to Calcium binding site number: 1; 2;

Calcium binding site 1 out of 2 in the Crystal Structure of Human E-Cadherin Bound By Mouse Monoclonal Antibody 66E8FAB


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 1 of Crystal Structure of Human E-Cadherin Bound By Mouse Monoclonal Antibody 66E8FAB within 5.0Å range: probe atom residue distance (Å) B Occ C:Ca401 b:46.9 occ:1.00 OD2 C:ASP235 2.3 39.8 1.0 ND2 C:ASN203 2.3 38.0 1.0 O C:ASN205 2.3 52.2 1.0 O C:ASN244 2.4 53.9 1.0 OD1 C:ASP235 2.4 56.1 1.0 OD2 C:ASP296 2.5 45.3 1.0 OD2 C:ASP237 2.6 47.8 1.0 CG C:ASP235 2.7 50.6 1.0 C C:ASN205 3.5 48.3 1.0 C C:ASN244 3.5 53.5 1.0 CG C:ASP296 3.6 51.3 1.0 CG C:ASP237 3.6 54.6 1.0 CG C:ASN203 3.6 50.1 1.0 CB C:ASP237 3.8 47.3 1.0 CB C:ASP296 4.0 51.0 1.0 N C:ASN205 4.1 50.2 1.0 OD1 C:ASN203 4.2 53.4 1.0 CB C:ASP235 4.2 51.1 1.0 CA C:ASN205 4.2 47.9 1.0 CB C:ASN244 4.3 47.8 1.0 CA C:ASN244 4.3 51.6 1.0 CB C:ASN205 4.5 46.8 1.0 N C:ALA245 4.5 53.1 1.0 N C:LYS206 4.5 49.1 1.0 CA C:ALA245 4.6 55.3 1.0 OD1 C:ASP296 4.6 50.2 1.0 CA C:LYS206 4.6 49.5 1.0 CB C:ASN203 4.7 41.0 1.0 OD1 C:ASP237 4.7 54.7 1.0 CD1 C:LEU302 4.7 46.6 1.0 CA C:ASN203 4.7 47.9 1.0 N C:ASP237 4.8 48.4 1.0 CD C:PRO207 4.9 47.9 1.0 C C:LYS206 4.9 49.7 1.0 C C:ASN203 4.9 47.4 1.0 N C:ASP204 4.9 45.0 1.0 CA C:ASP237 5.0 50.0 1.0 N C:PRO207 5.0 49.5 1.0

Calcium binding site 2 out of 2 in the Crystal Structure of Human E-Cadherin Bound By Mouse Monoclonal Antibody 66E8FAB


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 2 of Crystal Structure of Human E-Cadherin Bound By Mouse Monoclonal Antibody 66E8FAB within 5.0Å range: probe atom residue distance (Å) B Occ C:Ca404 b:54.1 occ:1.00 OE2 C:GLU170 2.3 73.9 1.0 O C:HOH501 2.4 56.5 1.0 OD1 C:ASP168 2.4 72.9 1.0 OD2 C:ASP204 2.4 53.4 1.0 OE2 C:GLU112 2.6 70.7 1.0 CG C:ASP204 3.2 48.0 1.0 CG C:ASP168 3.3 74.0 1.0 OD1 C:ASP204 3.3 51.6 1.0 CD C:GLU112 3.4 65.1 1.0 CD C:GLU170 3.4 70.9 1.0 OE1 C:GLU112 3.7 64.2 1.0 O L:HOH437 3.7 52.7 1.0 OD2 C:ASP168 3.8 81.0 1.0 NA C:NA405 3.9 48.9 1.0 OD1 C:ASN205 4.1 51.3 1.0 CB C:GLU170 4.1 61.7 1.0 N C:GLU170 4.1 64.5 1.0 CG C:GLU170 4.2 68.9 1.0 N C:ARG169 4.2 58.1 1.0 CB C:ASP168 4.3 66.4 1.0 CA C:ASP168 4.3 63.7 1.0 OD1 C:ASN113 4.4 70.4 1.0 OE1 C:GLU170 4.4 68.1 1.0 ND2 C:ASN113 4.5 61.8 1.0 C C:ASP168 4.6 69.0 1.0 CB C:ASP204 4.6 48.6 1.0 CG C:GLU112 4.7 62.5 1.0 CA C:GLU170 4.8 63.3 1.0 CG C:ASN113 4.9 62.9 1.0

M.J.Bolejack, J.Abendroth, A.Y.Maker, B.M.Gumbiner, D.D.Lorimer, P.S.Horanyi, T.E.Edwards. Crystal Structure of Human E-Cadherin Bound By Mouse Monoclonal Antibody 66E8FAB To Be Published.