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Calcium in PDB 7b1g: TRPC4 in Complex with Calmodulin

Calcium Binding Sites:

The binding sites of Calcium atom in the TRPC4 in Complex with Calmodulin (pdb code 7b1g). This binding sites where shown within 5.0 Angstroms radius around Calcium atom.
In total 4 binding sites of Calcium where determined in the TRPC4 in Complex with Calmodulin, PDB code: 7b1g:
Jump to Calcium binding site number: 1; 2; 3; 4;

Calcium binding site 1 out of 4 in 7b1g

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Calcium binding site 1 out of 4 in the TRPC4 in Complex with Calmodulin


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 1 of TRPC4 in Complex with Calmodulin within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Ca1001

b:65.7
occ:1.00
OE2 A:GLU417 2.4 71.7 1.0
OE1 A:GLN420 2.6 76.1 1.0
OD2 A:ASP438 2.6 68.2 1.0
OE1 A:GLU417 2.9 71.7 1.0
CD A:GLU417 3.1 71.7 1.0
CD A:GLN420 3.5 76.1 1.0
CG A:ASP438 3.7 68.2 1.0
NE2 A:GLN420 3.8 76.1 1.0
OD1 A:ASP438 4.1 68.2 1.0
OD1 A:ASN435 4.1 64.6 1.0
NH2 A:ARG491 4.2 48.7 1.0
CG A:ASN435 4.3 64.6 1.0
CA A:ASN435 4.5 64.6 1.0
CG A:GLU417 4.6 71.7 1.0
CB A:ASN435 4.6 64.6 1.0
ND2 A:ASN435 4.8 64.6 1.0
CG A:GLN420 4.9 76.1 1.0
CB A:ASP438 4.9 68.2 1.0

Calcium binding site 2 out of 4 in 7b1g

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Calcium binding site 2 out of 4 in the TRPC4 in Complex with Calmodulin


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 2 of TRPC4 in Complex with Calmodulin within 5.0Å range:
probe atom residue distance (Å) B Occ
B:Ca1003

b:62.5
occ:1.00
OD1 B:ASN435 2.5 69.3 1.0
OE1 B:GLU417 2.5 73.0 1.0
OE2 B:GLU417 2.5 73.0 1.0
CD B:GLU417 2.8 73.0 1.0
OD1 B:ASP438 3.0 67.8 1.0
CG B:ASN435 3.7 69.3 1.0
CG B:ASP438 4.2 67.8 1.0
NE2 B:GLN420 4.3 79.0 1.0
NH2 B:ARG491 4.3 48.1 1.0
CD B:GLN420 4.3 79.0 1.0
CG B:GLU417 4.4 73.0 1.0
ND2 B:ASN435 4.4 69.3 1.0
OE1 B:GLN420 4.5 79.0 1.0
CB B:ASN435 4.8 69.3 1.0
CB B:ASP438 4.8 67.8 1.0
CA B:ASN435 4.9 69.3 1.0
CE1 B:TYR429 4.9 83.2 1.0
CG B:GLN420 4.9 79.0 1.0

Calcium binding site 3 out of 4 in 7b1g

Go back to Calcium Binding Sites List in 7b1g
Calcium binding site 3 out of 4 in the TRPC4 in Complex with Calmodulin


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 3 of TRPC4 in Complex with Calmodulin within 5.0Å range:
probe atom residue distance (Å) B Occ
C:Ca1001

b:72.6
occ:1.00
OE1 C:GLN420 2.4 75.9 1.0
OD2 C:ASP438 2.4 68.2 1.0
OE1 C:GLU417 2.6 73.0 1.0
CD C:GLN420 3.2 75.9 1.0
ND2 C:ASN435 3.3 68.1 1.0
NE2 C:GLN420 3.5 75.9 1.0
CG C:ASP438 3.6 68.2 1.0
CD C:GLU417 3.8 73.0 1.0
NH2 C:ARG491 4.1 45.8 1.0
CG C:GLU417 4.4 73.0 1.0
OD1 C:ASP438 4.4 68.2 1.0
CB C:ASP438 4.4 68.2 1.0
CG C:ASN435 4.6 68.1 1.0
CG C:GLN420 4.6 75.9 1.0
OE2 C:GLU417 4.8 73.0 1.0
NE C:ARG491 5.0 45.8 1.0

Calcium binding site 4 out of 4 in 7b1g

Go back to Calcium Binding Sites List in 7b1g
Calcium binding site 4 out of 4 in the TRPC4 in Complex with Calmodulin


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 4 of TRPC4 in Complex with Calmodulin within 5.0Å range:
probe atom residue distance (Å) B Occ
D:Ca1001

b:58.6
occ:1.00
OD1 D:ASP438 2.4 67.0 1.0
OE1 D:GLN420 2.7 77.5 1.0
OD1 D:ASN435 3.2 69.2 1.0
NE2 D:GLN420 3.5 77.5 1.0
CD D:GLN420 3.5 77.5 1.0
OE2 D:GLU417 3.5 72.4 1.0
CG D:ASP438 3.7 67.0 1.0
NH2 D:ARG491 3.9 46.8 1.0
OE1 D:GLU417 4.1 72.4 1.0
CD D:GLU417 4.2 72.4 1.0
CG D:ASN435 4.3 69.2 1.0
CB D:ASP438 4.5 67.0 1.0
OD2 D:ASP438 4.5 67.0 1.0
ND2 D:ASN435 4.8 69.2 1.0
CG D:GLN420 4.9 77.5 1.0

Reference:

D.Vinayagam, D.Quentin, J.Yu-Strzelczyk, O.Sitsel, F.Merino, M.Stabrin, O.Hofnagel, M.Yu, M.W.Ledeboer, G.Nagel, G.Malojcic, S.Raunser. Structural Basis of TRPC4 Regulation By Calmodulin and Pharmacological Agents. Elife V. 9 2020.
ISSN: ESSN 2050-084X
PubMed: 33236980
DOI: 10.7554/ELIFE.60603
Page generated: Wed Jul 9 20:55:03 2025

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