Calcium in PDB 7b1g: TRPC4 in Complex with Calmodulin

The binding sites of Calcium atom in the TRPC4 in Complex with Calmodulin (pdb code 7b1g). This binding sites where shown within 5.0 Angstroms radius around Calcium atom.
In total 4 binding sites of Calcium where determined in the TRPC4 in Complex with Calmodulin, PDB code: 7b1g:
Jump to Calcium binding site number: 1; 2; 3; 4;

Calcium binding site 1 out of 4 in the TRPC4 in Complex with Calmodulin


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 1 of TRPC4 in Complex with Calmodulin within 5.0Å range: probe atom residue distance (Å) B Occ A:Ca1001 b:65.7 occ:1.00 OE2 A:GLU417 2.4 71.7 1.0 OE1 A:GLN420 2.6 76.1 1.0 OD2 A:ASP438 2.6 68.2 1.0 OE1 A:GLU417 2.9 71.7 1.0 CD A:GLU417 3.1 71.7 1.0 CD A:GLN420 3.5 76.1 1.0 CG A:ASP438 3.7 68.2 1.0 NE2 A:GLN420 3.8 76.1 1.0 OD1 A:ASP438 4.1 68.2 1.0 OD1 A:ASN435 4.1 64.6 1.0 NH2 A:ARG491 4.2 48.7 1.0 CG A:ASN435 4.3 64.6 1.0 CA A:ASN435 4.5 64.6 1.0 CG A:GLU417 4.6 71.7 1.0 CB A:ASN435 4.6 64.6 1.0 ND2 A:ASN435 4.8 64.6 1.0 CG A:GLN420 4.9 76.1 1.0 CB A:ASP438 4.9 68.2 1.0

Calcium binding site 2 out of 4 in the TRPC4 in Complex with Calmodulin


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 2 of TRPC4 in Complex with Calmodulin within 5.0Å range: probe atom residue distance (Å) B Occ B:Ca1003 b:62.5 occ:1.00 OD1 B:ASN435 2.5 69.3 1.0 OE1 B:GLU417 2.5 73.0 1.0 OE2 B:GLU417 2.5 73.0 1.0 CD B:GLU417 2.8 73.0 1.0 OD1 B:ASP438 3.0 67.8 1.0 CG B:ASN435 3.7 69.3 1.0 CG B:ASP438 4.2 67.8 1.0 NE2 B:GLN420 4.3 79.0 1.0 NH2 B:ARG491 4.3 48.1 1.0 CD B:GLN420 4.3 79.0 1.0 CG B:GLU417 4.4 73.0 1.0 ND2 B:ASN435 4.4 69.3 1.0 OE1 B:GLN420 4.5 79.0 1.0 CB B:ASN435 4.8 69.3 1.0 CB B:ASP438 4.8 67.8 1.0 CA B:ASN435 4.9 69.3 1.0 CE1 B:TYR429 4.9 83.2 1.0 CG B:GLN420 4.9 79.0 1.0

Calcium binding site 3 out of 4 in the TRPC4 in Complex with Calmodulin


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 3 of TRPC4 in Complex with Calmodulin within 5.0Å range: probe atom residue distance (Å) B Occ C:Ca1001 b:72.6 occ:1.00 OE1 C:GLN420 2.4 75.9 1.0 OD2 C:ASP438 2.4 68.2 1.0 OE1 C:GLU417 2.6 73.0 1.0 CD C:GLN420 3.2 75.9 1.0 ND2 C:ASN435 3.3 68.1 1.0 NE2 C:GLN420 3.5 75.9 1.0 CG C:ASP438 3.6 68.2 1.0 CD C:GLU417 3.8 73.0 1.0 NH2 C:ARG491 4.1 45.8 1.0 CG C:GLU417 4.4 73.0 1.0 OD1 C:ASP438 4.4 68.2 1.0 CB C:ASP438 4.4 68.2 1.0 CG C:ASN435 4.6 68.1 1.0 CG C:GLN420 4.6 75.9 1.0 OE2 C:GLU417 4.8 73.0 1.0 NE C:ARG491 5.0 45.8 1.0

Calcium binding site 4 out of 4 in the TRPC4 in Complex with Calmodulin


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 4 of TRPC4 in Complex with Calmodulin within 5.0Å range: probe atom residue distance (Å) B Occ D:Ca1001 b:58.6 occ:1.00 OD1 D:ASP438 2.4 67.0 1.0 OE1 D:GLN420 2.7 77.5 1.0 OD1 D:ASN435 3.2 69.2 1.0 NE2 D:GLN420 3.5 77.5 1.0 CD D:GLN420 3.5 77.5 1.0 OE2 D:GLU417 3.5 72.4 1.0 CG D:ASP438 3.7 67.0 1.0 NH2 D:ARG491 3.9 46.8 1.0 OE1 D:GLU417 4.1 72.4 1.0 CD D:GLU417 4.2 72.4 1.0 CG D:ASN435 4.3 69.2 1.0 CB D:ASP438 4.5 67.0 1.0 OD2 D:ASP438 4.5 67.0 1.0 ND2 D:ASN435 4.8 69.2 1.0 CG D:GLN420 4.9 77.5 1.0

D.Vinayagam, D.Quentin, J.Yu-Strzelczyk, O.Sitsel, F.Merino, M.Stabrin, O.Hofnagel, M.Yu, M.W.Ledeboer, G.Nagel, G.Malojcic, S.Raunser. Structural Basis of TRPC4 Regulation By Calmodulin and Pharmacological Agents. Elife V. 9 2020.
ISSN: ESSN 2050-084X
PubMed: 33236980
DOI: 10.7554/ELIFE.60603