Calcium in PDB 7b5c: Structure of Calcium-Bound MTMEM16A(Ac) Chloride Channel at 3.7 A Resolution

The binding sites of Calcium atom in the Structure of Calcium-Bound MTMEM16A(Ac) Chloride Channel at 3.7 A Resolution (pdb code 7b5c). This binding sites where shown within 5.0 Angstroms radius around Calcium atom.
In total 4 binding sites of Calcium where determined in the Structure of Calcium-Bound MTMEM16A(Ac) Chloride Channel at 3.7 A Resolution, PDB code: 7b5c:
Jump to Calcium binding site number: 1; 2; 3; 4;

Calcium binding site 1 out of 4 in the Structure of Calcium-Bound MTMEM16A(Ac) Chloride Channel at 3.7 A Resolution


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 1 of Structure of Calcium-Bound MTMEM16A(Ac) Chloride Channel at 3.7 A Resolution within 5.0Å range: probe atom residue distance (Å) B Occ A:Ca1001 b:25.1 occ:1.00 OE1 A:GLU705 2.5 24.5 1.0 OE1 A:GLU654 2.5 32.5 1.0 OE1 A:GLU702 2.5 28.4 1.0 OE2 A:GLU734 2.5 23.7 1.0 OE2 A:GLU702 2.8 28.4 1.0 OE2 A:GLU705 2.8 24.5 1.0 CD A:GLU705 2.8 24.5 1.0 CD A:GLU702 3.0 28.4 1.0 CD A:GLU654 3.1 32.5 1.0 OE2 A:GLU654 3.1 32.5 1.0 CD A:GLU734 3.4 23.7 1.0 OD1 A:ASN650 3.6 25.9 1.0 OE1 A:GLU734 3.7 23.7 1.0 CG A:GLU705 4.1 24.5 1.0 CB A:GLU705 4.2 24.5 1.0 OD1 A:ASP738 4.2 27.0 1.0 CA A:CA1002 4.4 26.1 1.0 CG A:GLU654 4.4 32.5 1.0 ND2 A:ASN650 4.4 25.9 1.0 CG A:ASN650 4.5 25.9 1.0 CG A:GLU702 4.5 28.4 1.0 CG A:GLU734 4.6 23.7 1.0 OD2 A:ASP738 4.7 27.0 1.0 CA A:GLU702 4.9 28.4 1.0 CG A:ASP738 4.9 27.0 1.0 CB A:GLU654 4.9 32.5 1.0

Calcium binding site 2 out of 4 in the Structure of Calcium-Bound MTMEM16A(Ac) Chloride Channel at 3.7 A Resolution


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 2 of Structure of Calcium-Bound MTMEM16A(Ac) Chloride Channel at 3.7 A Resolution within 5.0Å range: probe atom residue distance (Å) B Occ A:Ca1002 b:26.1 occ:1.00 OE1 A:GLU734 2.6 23.7 1.0 OD1 A:ASN650 2.6 25.9 1.0 OD1 A:ASN651 2.8 27.1 1.0 OD1 A:ASN730 2.9 20.1 1.0 CD A:GLU734 3.5 23.7 1.0 ND2 A:ASN730 3.6 20.1 1.0 O A:GLN646 3.6 24.1 1.0 CG A:ASN650 3.6 25.9 1.0 CG A:ASN730 3.6 20.1 1.0 CG A:ASN651 3.8 27.1 1.0 CB A:ASN650 4.2 25.9 1.0 OE2 A:GLU734 4.3 23.7 1.0 ND2 A:ASN651 4.3 27.1 1.0 CG A:GLU734 4.4 23.7 1.0 CA A:CA1001 4.4 25.1 1.0 C A:GLN646 4.5 24.1 1.0 CB A:GLU734 4.6 23.7 1.0 ND2 A:ASN650 4.7 25.9 1.0 OE1 A:GLU654 4.7 32.5 1.0 N A:ASN651 4.8 27.1 1.0 O A:ASN730 4.9 20.1 1.0 OE1 A:GLN646 4.9 24.1 1.0

Calcium binding site 3 out of 4 in the Structure of Calcium-Bound MTMEM16A(Ac) Chloride Channel at 3.7 A Resolution


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 3 of Structure of Calcium-Bound MTMEM16A(Ac) Chloride Channel at 3.7 A Resolution within 5.0Å range: probe atom residue distance (Å) B Occ B:Ca1001 b:26.1 occ:1.00 OE1 B:GLU705 2.5 24.9 1.0 OE1 B:GLU654 2.5 32.6 1.0 OE1 B:GLU702 2.5 28.7 1.0 OE2 B:GLU734 2.5 23.4 1.0 OE2 B:GLU702 2.8 28.7 1.0 OE2 B:GLU705 2.8 24.9 1.0 CD B:GLU705 2.8 24.9 1.0 CD B:GLU702 3.0 28.7 1.0 CD B:GLU654 3.1 32.6 1.0 OE2 B:GLU654 3.1 32.6 1.0 CD B:GLU734 3.4 23.4 1.0 OD1 B:ASN650 3.6 25.4 1.0 OE1 B:GLU734 3.7 23.4 1.0 CG B:GLU705 4.1 24.9 1.0 CB B:GLU705 4.2 24.9 1.0 OD1 B:ASP738 4.2 26.8 1.0 CA B:CA1002 4.4 25.3 1.0 CG B:GLU654 4.4 32.6 1.0 ND2 B:ASN650 4.4 25.4 1.0 CG B:ASN650 4.5 25.4 1.0 CG B:GLU702 4.5 28.7 1.0 CG B:GLU734 4.6 23.4 1.0 OD2 B:ASP738 4.7 26.8 1.0 CA B:GLU702 4.9 28.7 1.0 CG B:ASP738 4.9 26.8 1.0 CB B:GLU654 4.9 32.6 1.0

Calcium binding site 4 out of 4 in the Structure of Calcium-Bound MTMEM16A(Ac) Chloride Channel at 3.7 A Resolution


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 4 of Structure of Calcium-Bound MTMEM16A(Ac) Chloride Channel at 3.7 A Resolution within 5.0Å range: probe atom residue distance (Å) B Occ B:Ca1002 b:25.3 occ:1.00 OE1 B:GLU734 2.6 23.4 1.0 OD1 B:ASN650 2.6 25.4 1.0 OD1 B:ASN651 2.8 26.8 1.0 OD1 B:ASN730 2.9 19.5 1.0 CD B:GLU734 3.5 23.4 1.0 ND2 B:ASN730 3.6 19.5 1.0 O B:GLN646 3.6 23.4 1.0 CG B:ASN650 3.6 25.4 1.0 CG B:ASN730 3.6 19.5 1.0 CG B:ASN651 3.8 26.8 1.0 CB B:ASN650 4.2 25.4 1.0 OE2 B:GLU734 4.2 23.4 1.0 ND2 B:ASN651 4.3 26.8 1.0 CG B:GLU734 4.4 23.4 1.0 CA B:CA1001 4.4 26.1 1.0 C B:GLN646 4.5 23.4 1.0 CB B:GLU734 4.6 23.4 1.0 ND2 B:ASN650 4.7 25.4 1.0 OE1 B:GLU654 4.7 32.6 1.0 N B:ASN651 4.8 26.8 1.0 O B:ASN730 4.9 19.5 1.0 OE1 B:GLN646 4.9 23.4 1.0

A.K.M.Lam, J.Rheinberger, C.Paulino, R.Dutzler. Gating the Pore of the Calcium-Activated Chloride Channel TMEM16A Nat Commun 2021.
ISSN: ESSN 2041-1723
DOI: 10.1038/S41467-020-20787-9