Calcium in PDB 7bgr: 14-3-3 Sigma with PIN1 Binding Site PS72 and Covalently Bound LVD1016

Enzymatic activity of 14-3-3 Sigma with PIN1 Binding Site PS72 and Covalently Bound LVD1016

All present enzymatic activity of 14-3-3 Sigma with PIN1 Binding Site PS72 and Covalently Bound LVD1016:
5.2.1.8;

Protein crystallography data

The structure of 14-3-3 Sigma with PIN1 Binding Site PS72 and Covalently Bound LVD1016, PDB code: 7bgr was solved by M.Wolter, L.V.Dijck, P.J.Cossar, C.Ottmann, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

*Resolution Low / High (Å)*	34.32 / 1.80
*Space group*	C 2 2 2₁
*Cell size a, b, c (Å), α, β, γ (°)*	82.19, 111.68, 62.393, 90, 90, 90
*R / R_free (%)*	17 / 21.1

Other elements in 7bgr:

The structure of 14-3-3 Sigma with PIN1 Binding Site PS72 and Covalently Bound LVD1016 also contains other interesting chemical elements:

Chlorine

(Cl)

1 atom

Calcium Binding Sites:

The binding sites of Calcium atom in the 14-3-3 Sigma with PIN1 Binding Site PS72 and Covalently Bound LVD1016 (pdb code 7bgr). This binding sites where shown within 5.0 Angstroms radius around Calcium atom.
In total only one binding site of Calcium was determined in the 14-3-3 Sigma with PIN1 Binding Site PS72 and Covalently Bound LVD1016, PDB code: 7bgr:

Calcium binding site 1 out of 1 in 7bgr

Go back to

Calcium Binding Sites List in 7bgr

Calcium binding site 1 out of 1 in the 14-3-3 Sigma with PIN1 Binding Site PS72 and Covalently Bound LVD1016

Mono view

Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 1 of 14-3-3 Sigma with PIN1 Binding Site PS72 and Covalently Bound LVD1016 within 5.0Å range:

probe	atom	residue	distance (Å)	B	Occ
A:Ca302 b:18.3 occ:1.00	O	A:GLU110	2.3	12.4	1.0
	OE1	A:GLU35	2.3	18.1	1.0
	O	A:HOH548	2.3	25.1	1.0
	O	A:HOH600	2.4	20.2	1.0
	OE2	A:GLU35	2.8	24.1	1.0
	CD	A:GLU35	2.9	24.5	1.0
	C	A:GLU110	3.5	14.4	1.0
	N	A:GLY112	4.0	14.7	1.0
	O	A:HOH601	4.0	36.6	1.0
	CG	A:GLU35	4.3	12.9	1.0
	CA	A:GLU110	4.3	8.7	1.0
	N	A:ALA111	4.4	10.1	1.0
	O	A:HOH556	4.5	24.6	1.0
	CB	A:GLU110	4.5	9.9	1.0
	CA	A:ALA111	4.5	8.9	1.0
	O	A:HOH619	4.6	29.8	1.0
	OE1	A:GLU110	4.6	24.6	1.0
	C	A:ALA111	4.7	10.1	1.0
	CA	A:GLY112	4.7	17.3	1.0
	O	A:HOH563	4.8	31.2	1.0

Reference:

P.J.Cossar, M.Wolter, L.Van Dijck, D.Valenti, L.M.Levy, C.Ottmann, L.Brunsveld. Reversible Covalent Imine-Tethering For Selective Stabilization of 14-3-3 Hub Protein Interactions. J.Am.Chem.Soc. 2021.
ISSN: ESSN 1520-5126
PubMed: 34047554
DOI: 10.1021/JACS.1C03035

Page generated: Thu Jul 18 23:17:14 2024

Last articles

Zn in 9JPJ
Zn in 9JP7
Zn in 9JPK
Zn in 9JPL
Zn in 9GN6
Zn in 9GN7
Zn in 9GKU
Zn in 9GKW
Zn in 9GKX
Zn in 9GL0

	© Copyright 2008-2020 by atomistry.com
Home \| Site Map \| Copyright \| Contact us \| Privacy