Calcium in PDB 7cqp: Complex of TRPC4 and CALMODULIN_NLOBE

The structure of Complex of TRPC4 and CALMODULIN_NLOBE, PDB code: 7cqp was solved by Z.S.Shen, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	40.99 / 1.90
Space group	P 61 2 2
Cell size a, b, c (Å), α, β, γ (°)	64.46, 64.46, 120.751, 90, 90, 120
R / Rfree (%)	21.9 / 25

The binding sites of Calcium atom in the Complex of TRPC4 and CALMODULIN_NLOBE (pdb code 7cqp). This binding sites where shown within 5.0 Angstroms radius around Calcium atom.
In total 2 binding sites of Calcium where determined in the Complex of TRPC4 and CALMODULIN_NLOBE, PDB code: 7cqp:
Jump to Calcium binding site number: 1; 2;

Calcium binding site 1 out of 2 in the Complex of TRPC4 and CALMODULIN_NLOBE


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 1 of Complex of TRPC4 and CALMODULIN_NLOBE within 5.0Å range: probe atom residue distance (Å) B Occ B:Ca101 b:22.3 occ:1.00 OD1 B:ASP57 2.2 25.6 1.0 OD1 B:ASN61 2.4 27.0 1.0 O B:THR63 2.4 22.5 1.0 OE2 B:GLU68 2.4 21.6 1.0 OD1 B:ASP59 2.4 26.9 1.0 OE1 B:GLU68 2.5 24.2 1.0 O B:HOH218 2.5 29.2 1.0 CD B:GLU68 2.8 23.0 1.0 CG B:ASP59 3.3 29.0 1.0 CG B:ASN61 3.3 27.1 1.0 CG B:ASP57 3.4 26.1 1.0 C B:THR63 3.6 24.9 1.0 OD2 B:ASP59 3.7 30.9 1.0 ND2 B:ASN61 4.0 28.9 1.0 OD2 B:ASP57 4.1 27.3 1.0 N B:ASN61 4.2 28.2 1.0 N B:THR63 4.3 26.1 1.0 CG B:GLU68 4.3 22.1 1.0 CA B:ASP57 4.3 25.0 1.0 N B:ASP59 4.3 26.8 1.0 CB B:ASP57 4.4 25.8 1.0 CA B:ILE64 4.4 21.0 1.0 N B:ILE64 4.4 21.1 1.0 CB B:ASN61 4.4 29.1 1.0 CB B:ASP59 4.5 30.0 1.0 CA B:THR63 4.6 23.2 1.0 N B:ASP65 4.6 20.0 1.0 N B:GLY60 4.6 32.5 1.0 C B:ASP57 4.6 27.4 1.0 N B:GLY62 4.7 25.8 1.0 N B:ALA58 4.7 25.5 1.0 CA B:ASN61 4.7 27.0 1.0 OG1 B:THR63 4.7 25.5 1.0 CD1 B:ILE64 4.7 21.8 1.0 CA B:ASP59 4.8 30.0 1.0 C B:ASP59 4.9 31.1 1.0 C B:ASN61 4.9 26.9 1.0 OD2 B:ASP65 4.9 28.0 1.0 CG B:ASP65 4.9 22.3 1.0 C B:ILE64 4.9 18.7 1.0

Calcium binding site 2 out of 2 in the Complex of TRPC4 and CALMODULIN_NLOBE


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 2 of Complex of TRPC4 and CALMODULIN_NLOBE within 5.0Å range: probe atom residue distance (Å) B Occ B:Ca102 b:26.1 occ:1.00 O B:THR27 2.3 28.3 1.0 OD1 B:ASP21 2.3 28.3 1.0 OE1 B:GLU32 2.3 29.1 1.0 OD1 B:ASP23 2.4 32.1 1.0 OD1 B:ASP25 2.4 32.7 1.0 OE2 B:GLU32 2.5 26.6 1.0 O B:HOH219 2.5 28.8 1.0 CD B:GLU32 2.7 27.7 1.0 CG B:ASP23 3.3 34.4 1.0 CG B:ASP25 3.3 33.5 1.0 CG B:ASP21 3.5 29.2 1.0 C B:THR27 3.5 23.8 1.0 OD2 B:ASP23 3.6 35.7 1.0 OD2 B:ASP25 3.9 36.2 1.0 CA B:ASP21 4.1 23.9 1.0 OG1 B:THR27 4.1 30.6 1.0 N B:THR27 4.1 26.4 1.0 N B:ASP25 4.2 33.6 1.0 CG B:GLU32 4.2 26.0 1.0 N B:ASP23 4.3 34.1 1.0 CB B:ASP21 4.3 23.6 1.0 C B:ASP21 4.3 28.7 1.0 OD2 B:ASP21 4.4 29.7 1.0 CA B:THR27 4.4 25.7 1.0 CB B:ASP25 4.4 33.7 1.0 N B:ILE28 4.5 19.9 1.0 N B:LYS22 4.5 28.8 1.0 N B:GLY24 4.5 33.1 1.0 CB B:ASP23 4.5 35.3 1.0 CA B:ILE28 4.6 19.3 1.0 CA B:ASP25 4.7 31.5 1.0 O B:HOH209 4.8 31.9 1.0 CA B:ASP23 4.8 34.4 1.0 N B:GLY26 4.8 28.9 1.0 CG2 B:THR29 4.9 25.2 1.0 C B:ASP23 4.9 35.6 1.0 N B:THR29 4.9 22.6 1.0 CB B:THR27 4.9 28.9 1.0 O B:ASP21 4.9 28.6 1.0 C B:ASP25 4.9 31.5 1.0

W.Chen, Z.Shen, S.Asteriti, Z.Chen, F.Ye, Z.Sun, J.Wan, C.Montell, R.C.Hardie, W.Liu, M.Zhang. Calmodulin Binds to Drosophila Trp with An Unexpected Mode. Structure V. 29 330 2021.
ISSN: ISSN 0969-2126
PubMed: 33326749
DOI: 10.1016/J.STR.2020.11.016