Calcium in PDB 7dd7: Structure of Calcium-Sensing Receptor in Complex with Evocalcet

The structure of Structure of Calcium-Sensing Receptor in Complex with Evocalcet also contains other interesting chemical elements:

Chlorine

(Cl)

2 atoms

The binding sites of Calcium atom in the Structure of Calcium-Sensing Receptor in Complex with Evocalcet (pdb code 7dd7). This binding sites where shown within 5.0 Angstroms radius around Calcium atom.
In total 6 binding sites of Calcium where determined in the Structure of Calcium-Sensing Receptor in Complex with Evocalcet, PDB code: 7dd7:
Jump to Calcium binding site number: 1; 2; 3; 4; 5; 6;

Calcium binding site 1 out of 6 in the Structure of Calcium-Sensing Receptor in Complex with Evocalcet


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 1 of Structure of Calcium-Sensing Receptor in Complex with Evocalcet within 5.0Å range: probe atom residue distance (Å) B Occ A:Ca1102 b:95.2 occ:1.00 OG A:SER302 2.3 78.7 1.0 CB A:SER302 3.4 78.7 1.0 CH2 A:TRP1107 3.5 64.9 1.0 CA A:GLY273 4.0 74.8 1.0 CD A:PRO274 4.1 75.4 1.0 CZ3 A:TRP1107 4.1 64.9 1.0 CA A:SER302 4.1 78.7 1.0 N A:GLY273 4.2 74.8 1.0 CE1 A:PHE42 4.4 78.2 1.0 O A:ALA298 4.5 65.8 1.0 CZ2 A:TRP1107 4.6 64.9 1.0 NH1 A:ARG66 4.6 67.0 1.0 OG A:SER272 4.7 74.3 1.0 CZ A:PHE42 4.9 78.2 1.0 N A:PRO274 5.0 75.4 1.0 CG A:LEU304 5.0 82.4 1.0

Calcium binding site 2 out of 6 in the Structure of Calcium-Sensing Receptor in Complex with Evocalcet


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 2 of Structure of Calcium-Sensing Receptor in Complex with Evocalcet within 5.0Å range: probe atom residue distance (Å) B Occ A:Ca1103 b:92.7 occ:1.00 OG1 A:THR100 2.5 75.8 1.0 CB A:THR100 2.7 75.8 1.0 CG2 A:THR100 2.8 75.8 1.0 CG1 A:VAL149 3.6 66.2 1.0 CG2 A:THR145 3.8 64.3 1.0 N A:THR145 4.1 64.3 1.0 CB A:VAL149 4.2 66.2 1.0 CA A:THR100 4.2 75.8 1.0 CG2 A:VAL149 4.2 66.2 1.0 CA A:ALA144 4.4 65.6 1.0 CA A:ASN102 4.6 76.2 1.0 C A:ALA144 4.6 65.6 1.0 N A:ASN102 4.6 76.2 1.0 N A:GLY146 4.7 67.1 1.0 C A:THR100 4.8 75.8 1.0 N A:PRO39 4.9 69.7 1.0 C A:PHE38 4.9 63.0 1.0 N A:ALA144 4.9 65.6 1.0 CB A:PRO39 4.9 69.7 1.0 CA A:THR145 4.9 64.3 1.0 N A:THR100 5.0 75.8 1.0 CB A:LEU37 5.0 60.9 1.0 OD1 A:ASN102 5.0 76.2 1.0 CB A:THR145 5.0 64.3 1.0 O A:LEU37 5.0 60.9 1.0

Calcium binding site 3 out of 6 in the Structure of Calcium-Sensing Receptor in Complex with Evocalcet


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 3 of Structure of Calcium-Sensing Receptor in Complex with Evocalcet within 5.0Å range: probe atom residue distance (Å) B Occ B:Ca1101 b:117.8 occ:1.00 O B:GLY556 3.5 122.0 1.0 OD1 A:ASP234 3.6 84.0 1.0 O A:GLU231 4.0 83.1 1.0 C B:GLY556 4.6 122.0 1.0 CG A:ASP234 4.7 84.0 1.0 OE2 A:GLU231 4.9 83.1 1.0

Calcium binding site 4 out of 6 in the Structure of Calcium-Sensing Receptor in Complex with Evocalcet


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 4 of Structure of Calcium-Sensing Receptor in Complex with Evocalcet within 5.0Å range: probe atom residue distance (Å) B Occ B:Ca1103 b:110.0 occ:1.00 OD1 B:ASP234 2.7 86.1 1.0 O A:GLY556 3.1 118.5 1.0 CG B:ASP234 3.5 86.1 1.0 OD2 B:ASP234 3.5 86.1 1.0 C A:GLY556 4.0 118.5 1.0 CA A:GLY556 4.2 118.5 1.0 O B:GLU232 4.3 83.6 1.0 O B:GLU231 4.6 82.6 1.0 CB B:ASP234 4.9 86.1 1.0 C B:GLU232 4.9 83.6 1.0 N B:ASP234 5.0 86.1 1.0

Calcium binding site 5 out of 6 in the Structure of Calcium-Sensing Receptor in Complex with Evocalcet


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 5 of Structure of Calcium-Sensing Receptor in Complex with Evocalcet within 5.0Å range: probe atom residue distance (Å) B Occ B:Ca1104 b:104.9 occ:1.00 OG B:SER302 2.4 78.3 1.0 CB B:SER302 3.5 78.3 1.0 CH2 B:TRP1109 4.0 61.9 1.0 CA B:SER302 4.1 78.3 1.0 CE1 B:PHE42 4.2 75.8 1.0 CZ3 B:TRP1109 4.2 61.9 1.0 CA B:GLY273 4.3 74.1 1.0 NH1 B:ARG66 4.4 70.1 1.0 N B:GLY273 4.5 74.1 1.0 CD B:PRO274 4.5 75.3 1.0 O B:ALA298 4.6 66.6 1.0 N B:SER303 4.6 82.6 1.0 CZ B:PHE42 4.6 75.8 1.0 C B:SER302 4.9 78.3 1.0

Calcium binding site 6 out of 6 in the Structure of Calcium-Sensing Receptor in Complex with Evocalcet


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 6 of Structure of Calcium-Sensing Receptor in Complex with Evocalcet within 5.0Å range: probe atom residue distance (Å) B Occ B:Ca1105 b:85.3 occ:1.00 O B:ALA144 2.3 63.3 1.0 OG1 B:THR100 2.7 73.5 1.0 CB B:THR100 3.4 73.5 1.0 C B:ALA144 3.5 63.3 1.0 CB B:THR145 3.6 62.0 1.0 CG2 B:THR100 3.7 73.5 1.0 CG1 B:VAL149 4.1 63.2 1.0 OG1 B:THR145 4.1 62.0 1.0 CG2 B:VAL149 4.1 63.2 1.0 CD B:PRO39 4.3 67.8 1.0 CB B:VAL149 4.3 63.2 1.0 N B:THR145 4.3 62.0 1.0 CB B:PRO39 4.3 67.8 1.0 N B:GLY146 4.3 63.2 1.0 CA B:THR145 4.4 62.0 1.0 CA B:ASN102 4.4 75.8 1.0 N B:PRO39 4.5 67.8 1.0 C B:THR145 4.5 62.0 1.0 CA B:ALA144 4.5 63.3 1.0 N B:ASN102 4.6 75.8 1.0 CG B:PRO39 4.6 67.8 1.0 CG2 B:THR145 4.6 62.0 1.0 OD1 B:ASN102 4.7 75.8 1.0 CA B:PRO39 4.8 67.8 1.0 CA B:THR100 4.8 73.5 1.0 C B:PHE38 4.9 62.9 1.0 O B:LEU37 4.9 60.4 1.0

T.L.Wen, Z.Y.Wang, X.Z.Chen, Y.Ren, X.H.Lu, Y.F.Xing, J.Lu, S.H.Chang, X.Zhang, Y.Q.Shen, X.Yang. Structural Basis For Activation and Allosteric Modulation of Full-Length Calcium-Sensing Receptor. Sci Adv 2021.
ISSN: ESSN 2375-2548
PubMed: 34088669
DOI: 10.1126/SCIADV.ABG1483