Calcium in PDB 7dxd: Structure of TRPC3 at 3.9 Angstrom in 1340 Nm Free Calcium State

The structure of Structure of TRPC3 at 3.9 Angstrom in 1340 Nm Free Calcium State also contains other interesting chemical elements:

Zinc

(Zn)

4 atoms

The binding sites of Calcium atom in the Structure of TRPC3 at 3.9 Angstrom in 1340 Nm Free Calcium State (pdb code 7dxd). This binding sites where shown within 5.0 Angstroms radius around Calcium atom.
In total 4 binding sites of Calcium where determined in the Structure of TRPC3 at 3.9 Angstrom in 1340 Nm Free Calcium State, PDB code: 7dxd:
Jump to Calcium binding site number: 1; 2; 3; 4;

Calcium binding site 1 out of 4 in the Structure of TRPC3 at 3.9 Angstrom in 1340 Nm Free Calcium State


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 1 of Structure of TRPC3 at 3.9 Angstrom in 1340 Nm Free Calcium State within 5.0Å range: probe atom residue distance (Å) B Occ A:Ca903 b:80.0 occ:1.00 O A:GLU73 2.5 79.7 1.0 OE1 A:GLU73 2.6 80.7 1.0 OD1 A:ASP798 2.9 84.4 1.0 CG A:ASP798 3.5 83.4 1.0 CD A:GLU73 3.6 78.6 1.0 C A:GLU73 3.7 73.8 1.0 OD2 A:ASP798 3.9 83.0 1.0 CB A:GLU73 4.3 73.5 1.0 OE2 A:GLU73 4.4 83.2 1.0 CA A:ASP798 4.5 84.3 1.0 NZ C:LYS796 4.5 73.7 1.0 CG A:GLU73 4.5 76.8 1.0 CB A:ASP798 4.6 81.0 1.0 N A:HIS74 4.6 72.6 1.0 CA A:HIS74 4.6 75.4 1.0 CA A:GLU73 4.6 72.2 1.0 N A:LEU75 4.7 75.7 1.0 N A:ASP798 4.8 82.0 1.0 OG A:SER801 5.0 103.9 1.0

Calcium binding site 2 out of 4 in the Structure of TRPC3 at 3.9 Angstrom in 1340 Nm Free Calcium State


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 2 of Structure of TRPC3 at 3.9 Angstrom in 1340 Nm Free Calcium State within 5.0Å range: probe atom residue distance (Å) B Occ B:Ca903 b:80.0 occ:1.00 O B:GLU73 2.5 79.7 1.0 OE1 B:GLU73 2.6 80.7 1.0 OD1 B:ASP798 2.9 84.4 1.0 CG B:ASP798 3.5 83.4 1.0 CD B:GLU73 3.6 78.6 1.0 C B:GLU73 3.7 73.8 1.0 OD2 B:ASP798 3.9 83.0 1.0 CB B:GLU73 4.3 73.5 1.0 OE2 B:GLU73 4.4 83.2 1.0 CA B:ASP798 4.5 84.3 1.0 NZ A:LYS796 4.5 73.7 1.0 CG B:GLU73 4.5 76.8 1.0 CB B:ASP798 4.6 81.0 1.0 N B:HIS74 4.6 72.6 1.0 CA B:HIS74 4.6 75.4 1.0 CA B:GLU73 4.6 72.2 1.0 N B:LEU75 4.7 75.7 1.0 N B:ASP798 4.8 82.0 1.0 OG B:SER801 5.0 103.9 1.0

Calcium binding site 3 out of 4 in the Structure of TRPC3 at 3.9 Angstrom in 1340 Nm Free Calcium State


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 3 of Structure of TRPC3 at 3.9 Angstrom in 1340 Nm Free Calcium State within 5.0Å range: probe atom residue distance (Å) B Occ C:Ca903 b:80.0 occ:1.00 O C:GLU73 2.5 79.7 1.0 OE1 C:GLU73 2.6 80.7 1.0 OD1 C:ASP798 2.9 84.4 1.0 CG C:ASP798 3.5 83.4 1.0 CD C:GLU73 3.6 78.6 1.0 C C:GLU73 3.7 73.8 1.0 OD2 C:ASP798 3.9 83.0 1.0 CB C:GLU73 4.3 73.5 1.0 OE2 C:GLU73 4.4 83.2 1.0 CA C:ASP798 4.5 84.3 1.0 NZ D:LYS796 4.5 73.7 1.0 CG C:GLU73 4.5 76.8 1.0 CB C:ASP798 4.6 81.0 1.0 N C:HIS74 4.6 72.6 1.0 CA C:HIS74 4.6 75.4 1.0 CA C:GLU73 4.6 72.2 1.0 N C:LEU75 4.7 75.7 1.0 N C:ASP798 4.8 82.0 1.0 OG C:SER801 5.0 103.9 1.0

Calcium binding site 4 out of 4 in the Structure of TRPC3 at 3.9 Angstrom in 1340 Nm Free Calcium State


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 4 of Structure of TRPC3 at 3.9 Angstrom in 1340 Nm Free Calcium State within 5.0Å range: probe atom residue distance (Å) B Occ D:Ca903 b:80.0 occ:1.00 O D:GLU73 2.5 79.7 1.0 OE1 D:GLU73 2.6 80.7 1.0 OD1 D:ASP798 2.9 84.4 1.0 CG D:ASP798 3.5 83.4 1.0 CD D:GLU73 3.6 78.6 1.0 C D:GLU73 3.7 73.8 1.0 OD2 D:ASP798 3.9 83.0 1.0 CB D:GLU73 4.3 73.5 1.0 OE2 D:GLU73 4.4 83.2 1.0 CA D:ASP798 4.5 84.3 1.0 NZ B:LYS796 4.5 73.7 1.0 CG D:GLU73 4.5 76.8 1.0 CB D:ASP798 4.6 81.0 1.0 N D:HIS74 4.6 72.6 1.0 CA D:HIS74 4.6 75.4 1.0 CA D:GLU73 4.6 72.2 1.0 N D:LEU75 4.7 75.7 1.0 N D:ASP798 4.8 82.0 1.0 OG D:SER801 5.0 103.9 1.0

W.Guo, Q.Tang, M.Wei, Y.Kang, J.X.Wu, L.Chen. Structural Mechanism of Human TRPC3 and TRPC6 Channel Regulation By Their Intracellular Calcium-Binding Sites. Neuron V. 110 1023 2022.
ISSN: ISSN 0896-6273
PubMed: 35051376
DOI: 10.1016/J.NEURON.2021.12.023