Calcium in PDB 7f4h: Cryo-Em Structure of Afamelanotide-Bound Melanocortin-1 Receptor in Complex with Gs Protein, NB35 and SCFV16

The binding sites of Calcium atom in the Cryo-Em Structure of Afamelanotide-Bound Melanocortin-1 Receptor in Complex with Gs Protein, NB35 and SCFV16 (pdb code 7f4h). This binding sites where shown within 5.0 Angstroms radius around Calcium atom.
In total only one binding site of Calcium was determined in the Cryo-Em Structure of Afamelanotide-Bound Melanocortin-1 Receptor in Complex with Gs Protein, NB35 and SCFV16, PDB code: 7f4h:

Calcium binding site 1 out of 1 in the Cryo-Em Structure of Afamelanotide-Bound Melanocortin-1 Receptor in Complex with Gs Protein, NB35 and SCFV16


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 1 of Cryo-Em Structure of Afamelanotide-Bound Melanocortin-1 Receptor in Complex with Gs Protein, NB35 and SCFV16 within 5.0Å range: probe atom residue distance (Å) B Occ R:Ca501 b:140.7 occ:1.00 O F:DPN7 2.3 20.0 1.0 OD1 R:ASP121 2.3 138.8 1.0 OD2 R:ASP121 2.3 138.8 1.0 OE2 R:GLU94 2.5 147.0 1.0 O F:GLU5 2.5 30.0 1.0 CG R:ASP121 2.6 138.8 1.0 OD1 R:ASP117 2.6 147.6 1.0 C F:DPN7 3.4 20.0 1.0 CG R:ASP117 3.5 147.6 1.0 C F:GLU5 3.7 30.0 1.0 CD R:GLU94 3.7 147.0 1.0 OD2 R:ASP117 3.7 147.6 1.0 N F:DPN7 3.8 20.0 1.0 NH1 F:ARG8 3.8 30.0 1.0 CA F:DPN7 4.0 20.0 1.0 CB R:ASP121 4.1 138.8 1.0 CG F:ARG8 4.1 30.0 1.0 C F:HIS6 4.3 30.0 1.0 O R:ASP117 4.3 147.6 1.0 CB F:DPN7 4.4 20.0 1.0 N F:ARG8 4.4 30.0 1.0 OE1 R:GLU94 4.4 147.0 1.0 N F:GLU5 4.5 30.0 1.0 N F:HIS6 4.6 30.0 1.0 CA F:GLU5 4.7 30.0 1.0 CA F:HIS6 4.7 30.0 1.0 CD1 F:DPN7 4.8 20.0 1.0 CG R:GLU94 4.8 147.0 1.0 CA F:ARG8 4.8 30.0 1.0 CZ F:ARG8 4.9 30.0 1.0 CA R:ASP121 4.9 138.8 1.0 CB R:ASP117 4.9 147.6 1.0 O F:HIS6 5.0 30.0 1.0

S.Ma, Y.Chen, A.Dai, W.Yin, J.Guo, D.Yang, F.Zhou, Y.Jiang, M.W.Wang, H.E.Xu. Structural Mechanism of Calcium-Mediated Hormone Recognition and G Beta Interaction By the Human Melanocortin-1 Receptor. Cell Res. 2021.
ISSN: ISSN 1001-0602
PubMed: 34453129
DOI: 10.1038/S41422-021-00557-Y