Calcium in PDB 7juf: C-Type Carbohydrate-Recognition Domain 4 of the Mannose Receptor Complexed with Man-ALPHA1-2MAN

The structure of C-Type Carbohydrate-Recognition Domain 4 of the Mannose Receptor Complexed with Man-ALPHA1-2MAN, PDB code: 7juf was solved by W.I.Weis, H.Feinberg, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	33.80 / 1.40
Space group	P 1 21 1
Cell size a, b, c (Å), α, β, γ (°)	34.414, 56.376, 61.37, 90, 100.92, 90
R / Rfree (%)	13.4 / 17.1

The binding sites of Calcium atom in the C-Type Carbohydrate-Recognition Domain 4 of the Mannose Receptor Complexed with Man-ALPHA1-2MAN (pdb code 7juf). This binding sites where shown within 5.0 Angstroms radius around Calcium atom.
In total 4 binding sites of Calcium where determined in the C-Type Carbohydrate-Recognition Domain 4 of the Mannose Receptor Complexed with Man-ALPHA1-2MAN, PDB code: 7juf:
Jump to Calcium binding site number: 1; 2; 3; 4;

Calcium binding site 1 out of 4 in the C-Type Carbohydrate-Recognition Domain 4 of the Mannose Receptor Complexed with Man-ALPHA1-2MAN


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 1 of C-Type Carbohydrate-Recognition Domain 4 of the Mannose Receptor Complexed with Man-ALPHA1-2MAN within 5.0Å range: probe atom residue distance (Å) B Occ A:Ca801 b:8.3 occ:1.00 OD1 A:ASP748 2.4 8.3 1.0 OD1 A:ASN727 2.4 9.8 1.0 OE1 A:GLU733 2.4 9.0 1.0 OD1 A:ASN747 2.4 8.0 1.0 O3 C:MAN2 2.5 10.7 1.0 O A:ASP748 2.5 8.1 1.0 OE1 A:GLU725 2.6 9.8 1.0 O4 C:MAN2 2.6 10.6 1.0 C3 C:MAN2 3.3 12.5 1.0 CG A:ASP748 3.4 7.9 1.0 CD A:GLU733 3.4 8.7 1.0 C4 C:MAN2 3.4 12.9 1.0 CG A:ASN727 3.4 10.4 1.0 CD A:GLU725 3.4 9.9 1.0 CG A:ASN747 3.5 8.7 1.0 C A:ASP748 3.5 7.2 1.0 OE2 A:GLU725 3.7 11.5 1.0 OE2 A:GLU733 3.7 10.6 1.0 N A:ASP748 3.8 7.0 1.0 ND2 A:ASN747 3.9 11.9 1.0 ND2 A:ASN727 3.9 11.6 1.0 CA A:ASP748 4.0 7.2 1.0 OD2 A:ASP748 4.1 8.9 1.0 N A:ASN727 4.2 9.9 1.0 CB A:ASP748 4.3 7.7 1.0 CB A:ASN727 4.6 10.2 1.0 CB A:TYR729 4.6 12.1 1.0 C A:ASN747 4.6 6.9 1.0 N A:TYR729 4.7 9.5 1.0 CG A:GLU733 4.7 8.4 1.0 CG A:GLU725 4.7 9.7 1.0 N A:ASN728 4.7 8.5 1.0 N A:ILE749 4.7 7.0 1.0 C2 C:MAN2 4.8 16.3 1.0 CB A:ASN747 4.8 7.9 1.0 CA A:ASN727 4.8 9.5 1.0 CB A:GLU733 4.8 8.0 1.0 C5 C:MAN2 4.8 16.6 1.0 CA A:ASN747 4.9 7.1 1.0

Calcium binding site 2 out of 4 in the C-Type Carbohydrate-Recognition Domain 4 of the Mannose Receptor Complexed with Man-ALPHA1-2MAN


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 2 of C-Type Carbohydrate-Recognition Domain 4 of the Mannose Receptor Complexed with Man-ALPHA1-2MAN within 5.0Å range: probe atom residue distance (Å) B Occ A:Ca802 b:8.5 occ:0.50 CA A:CA802 0.0 8.5 0.5 CA A:CA802 1.4 9.2 0.5 OE2 A:GLU677 2.3 12.2 1.0 O A:HOH939 2.3 12.1 0.5 O A:HOH1026 2.4 12.6 0.5 O A:HOH901 2.4 7.0 0.5 O A:HOH939 2.4 8.4 0.5 OD1 A:ASN673 2.6 10.7 1.0 OE1 A:GLU677 2.7 9.2 1.0 CD A:GLU677 2.9 8.6 1.0 OG A:SER671 3.4 7.4 0.5 CG A:ASN673 3.6 9.7 1.0 O A:SER671 4.0 11.1 1.0 CB A:ASN673 4.1 9.6 1.0 O A:HOH907 4.3 47.6 1.0 CG A:GLU677 4.4 8.2 1.0 CB A:SER671 4.5 7.7 0.5 CB A:SER671 4.6 7.4 0.5 C A:SER671 4.7 8.0 1.0 N A:ASN673 4.7 7.6 1.0 ND2 A:ASN673 4.7 9.9 1.0 OE1 A:GLN760 4.8 8.5 1.0 OD2 A:ASP712 4.8 9.8 1.0 O A:HOH982 4.9 25.6 1.0 O A:HOH1038 4.9 13.2 1.0 O A:HOH1033 5.0 33.8 1.0

Calcium binding site 3 out of 4 in the C-Type Carbohydrate-Recognition Domain 4 of the Mannose Receptor Complexed with Man-ALPHA1-2MAN


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 3 of C-Type Carbohydrate-Recognition Domain 4 of the Mannose Receptor Complexed with Man-ALPHA1-2MAN within 5.0Å range: probe atom residue distance (Å) B Occ A:Ca802 b:9.2 occ:0.50 CA A:CA802 0.0 9.2 0.5 CA A:CA802 1.4 8.5 0.5 O A:HOH901 1.7 7.0 0.5 OD1 A:ASN673 2.1 10.7 1.0 O A:HOH939 2.3 12.1 0.5 OE1 A:GLU677 2.3 9.2 1.0 OG A:SER671 2.5 7.4 0.5 O A:SER671 2.7 11.1 1.0 OE2 A:GLU677 2.7 12.2 1.0 O A:HOH939 2.8 8.4 0.5 CD A:GLU677 2.9 8.6 1.0 CG A:ASN673 3.2 9.7 1.0 C A:SER671 3.3 8.0 1.0 CB A:SER671 3.4 7.7 0.5 CB A:SER671 3.5 7.4 0.5 O A:HOH1026 3.5 12.6 0.5 CA A:SER671 3.9 6.9 0.5 CA A:SER671 3.9 6.8 0.5 CB A:ASN673 3.9 9.6 1.0 N A:ASN673 4.0 7.6 1.0 N A:ILE672 4.1 7.2 1.0 OE1 A:GLN760 4.2 8.5 1.0 ND2 A:ASN673 4.3 9.9 1.0 CG A:GLU677 4.4 8.2 1.0 N A:SER671 4.4 6.8 1.0 CA A:ILE672 4.4 6.7 1.0 OG A:SER671 4.6 7.4 0.5 OD2 A:ASP712 4.6 9.8 1.0 C A:ILE672 4.6 7.2 1.0 CZ A:PHE642 4.6 11.8 1.0 CA A:ASN673 4.6 8.2 1.0 OG A:SER714 4.9 9.0 1.0 CB A:GLU677 5.0 6.5 1.0 CE1 A:PHE642 5.0 10.6 1.0

Calcium binding site 4 out of 4 in the C-Type Carbohydrate-Recognition Domain 4 of the Mannose Receptor Complexed with Man-ALPHA1-2MAN


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 4 of C-Type Carbohydrate-Recognition Domain 4 of the Mannose Receptor Complexed with Man-ALPHA1-2MAN within 5.0Å range: probe atom residue distance (Å) B Occ B:Ca800 b:5.5 occ:1.00 OD1 B:ASP748 2.3 5.9 1.0 OD1 B:ASN747 2.4 5.7 1.0 OE1 B:GLU733 2.4 6.3 1.0 OD1 B:ASN727 2.5 5.8 1.0 O B:ASP748 2.5 5.6 1.0 O3 D:MAN2 2.5 6.1 1.0 O4 D:MAN2 2.6 6.0 1.0 OE1 B:GLU725 2.6 7.0 1.0 C3 D:MAN2 3.3 6.6 1.0 CG B:ASP748 3.3 5.6 1.0 C4 D:MAN2 3.4 6.2 1.0 CD B:GLU733 3.4 6.3 1.0 CG B:ASN747 3.4 5.4 1.0 CD B:GLU725 3.4 7.8 1.0 CG B:ASN727 3.5 5.8 1.0 C B:ASP748 3.5 5.0 1.0 OE2 B:GLU725 3.7 9.9 1.0 OE2 B:GLU733 3.7 7.0 1.0 N B:ASP748 3.7 4.8 1.0 ND2 B:ASN747 3.8 7.6 1.0 ND2 B:ASN727 4.0 7.6 1.0 CA B:ASP748 4.0 5.5 1.0 OD2 B:ASP748 4.1 6.3 1.0 CB B:ASP748 4.2 6.2 1.0 N B:ASN727 4.3 6.2 1.0 CB B:TYR729 4.4 7.6 1.0 N B:TYR729 4.6 6.3 1.0 C B:ASN747 4.6 5.1 1.0 CB B:ASN727 4.7 6.4 1.0 CG B:GLU733 4.7 6.2 1.0 N B:ILE749 4.7 6.0 1.0 CB B:ASN747 4.7 5.6 1.0 CG B:GLU725 4.7 7.1 1.0 N B:ASN728 4.7 6.2 1.0 C2 D:MAN2 4.8 7.2 1.0 C5 D:MAN2 4.8 8.8 1.0 CA B:ASN727 4.9 5.9 1.0 CA B:ASN747 4.9 5.3 1.0 CB B:GLU733 4.9 6.0 1.0

H.Feinberg, S.A.F.Jegouzo, Y.Lasanajak, D.F.Smith, K.Drickamer, M.E.Taylor, W.I.Weis. Structural Analysis of Carbohydrate Binding By the Macrophage Mannose Receptor CD206 J.Biol.Chem. 2021.
ISSN: ESSN 1083-351X