Calcium in PDB 7juh: C-Type Carbohydrate-Recognition Domain 4 of the Mannose Receptor Complexed with Man-ALPHA1-6MAN

The structure of C-Type Carbohydrate-Recognition Domain 4 of the Mannose Receptor Complexed with Man-ALPHA1-6MAN, PDB code: 7juh was solved by W.I.Weis, H.Feinberg, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	31.70 / 1.40
Space group	P 1 21 1
Cell size a, b, c (Å), α, β, γ (°)	31.922, 59.04, 34.846, 90, 114.48, 90
R / Rfree (%)	15.2 / 18.6

The binding sites of Calcium atom in the C-Type Carbohydrate-Recognition Domain 4 of the Mannose Receptor Complexed with Man-ALPHA1-6MAN (pdb code 7juh). This binding sites where shown within 5.0 Angstroms radius around Calcium atom.
In total 2 binding sites of Calcium where determined in the C-Type Carbohydrate-Recognition Domain 4 of the Mannose Receptor Complexed with Man-ALPHA1-6MAN, PDB code: 7juh:
Jump to Calcium binding site number: 1; 2;

Calcium binding site 1 out of 2 in the C-Type Carbohydrate-Recognition Domain 4 of the Mannose Receptor Complexed with Man-ALPHA1-6MAN


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 1 of C-Type Carbohydrate-Recognition Domain 4 of the Mannose Receptor Complexed with Man-ALPHA1-6MAN within 5.0Å range: probe atom residue distance (Å) B Occ A:Ca801 b:13.2 occ:1.00 OD1 A:ASN727 2.4 14.5 1.0 OD1 A:ASP748 2.4 14.2 1.0 OD1 A:ASN747 2.4 14.9 1.0 O A:ASP748 2.4 12.6 1.0 OE1 A:GLU733 2.5 13.9 1.0 O3 A:MAN803 2.5 14.9 0.2 OE1 A:GLU725 2.5 16.7 1.0 O4 A:MAN803 2.5 15.3 0.2 O3 A:MAN803 2.5 17.3 0.8 O4 A:MAN803 2.6 17.2 0.8 C3 A:MAN803 3.3 16.9 0.2 C4 A:MAN803 3.4 16.7 0.2 C4 A:MAN803 3.4 22.4 0.8 CG A:ASP748 3.4 13.7 1.0 CD A:GLU733 3.4 13.6 1.0 C3 A:MAN803 3.4 21.4 0.8 CD A:GLU725 3.4 17.1 1.0 CG A:ASN747 3.4 13.7 1.0 CG A:ASN727 3.4 14.9 1.0 C A:ASP748 3.5 11.2 1.0 OE2 A:GLU733 3.7 15.4 1.0 OE2 A:GLU725 3.7 20.8 1.0 N A:ASP748 3.8 12.1 1.0 ND2 A:ASN747 3.8 16.8 1.0 CA A:ASP748 4.0 11.9 1.0 ND2 A:ASN727 4.0 16.9 1.0 OD2 A:ASP748 4.2 15.6 1.0 N A:ASN727 4.2 13.6 1.0 CB A:ASP748 4.3 13.4 1.0 CB A:ASN727 4.6 15.1 1.0 N A:ILE749 4.6 11.4 1.0 C A:ASN747 4.6 12.2 1.0 CG A:GLU725 4.7 15.8 1.0 N A:ASN728 4.7 12.8 1.0 CG A:GLU733 4.7 13.6 1.0 CB A:ASN747 4.7 13.2 1.0 C2 A:MAN803 4.8 19.6 0.2 N A:TYR729 4.8 14.0 1.0 CB A:TYR729 4.8 17.4 1.0 C5 A:MAN803 4.8 19.2 0.2 C5 A:MAN803 4.8 29.0 0.8 C2 A:MAN803 4.8 27.1 0.8 CA A:ASN727 4.8 13.1 1.0 CB A:GLU733 4.9 13.4 1.0 CA A:ASN747 4.9 12.0 1.0 O2 A:MAN803 5.0 28.7 0.8 O2 A:MAN803 5.0 18.4 0.2

Calcium binding site 2 out of 2 in the C-Type Carbohydrate-Recognition Domain 4 of the Mannose Receptor Complexed with Man-ALPHA1-6MAN


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 2 of C-Type Carbohydrate-Recognition Domain 4 of the Mannose Receptor Complexed with Man-ALPHA1-6MAN within 5.0Å range: probe atom residue distance (Å) B Occ A:Ca802 b:24.4 occ:0.75 OD1 A:ASN673 2.3 26.0 1.0 O A:HOH909 2.3 28.0 1.0 O A:HOH980 2.3 36.1 1.0 OE1 A:GLU677 2.4 25.3 1.0 OE2 A:GLU677 2.5 27.6 1.0 O A:SER671 2.5 20.6 1.0 OG A:SER671 2.5 21.9 1.0 CD A:GLU677 2.8 26.0 1.0 C A:SER671 3.3 17.4 1.0 CG A:ASN673 3.4 24.4 1.0 CB A:SER671 3.6 18.5 1.0 CA A:SER671 4.0 15.8 1.0 N A:ASN673 4.1 21.6 1.0 CB A:ASN673 4.2 24.8 1.0 N A:ILE672 4.2 17.4 1.0 OE1 A:GLN760 4.2 21.8 1.0 CG A:GLU677 4.3 26.6 1.0 N A:SER671 4.4 17.6 1.0 ND2 A:ASN673 4.5 25.6 1.0 CA A:ILE672 4.5 18.9 1.0 OD2 A:ASP712 4.6 25.9 1.0 CZ A:PHE642 4.7 20.8 1.0 C A:ILE672 4.8 20.0 1.0 CA A:ASN673 4.8 23.6 1.0 OG A:SER714 4.9 26.2 1.0

H.Feinberg, S.A.F.Jegouzo, Y.Lasanajak, D.F.Smith, K.Drickamer, M.E.Taylor, W.I.Weis. Structural Analysis of Carbohydrate Binding By the Macrophage Mannose Receptor CD206 J.Biol.Chem. 2021.
ISSN: ESSN 1083-351X