Calcium in PDB 7k4b: Cryo-Em Structure of Human TRPV6 in Complex with (4- Phenylcyclohexyl)Piperazine Inhibitor Cis-22A

The binding sites of Calcium atom in the Cryo-Em Structure of Human TRPV6 in Complex with (4- Phenylcyclohexyl)Piperazine Inhibitor Cis-22A (pdb code 7k4b). This binding sites where shown within 5.0 Angstroms radius around Calcium atom.
In total only one binding site of Calcium was determined in the Cryo-Em Structure of Human TRPV6 in Complex with (4- Phenylcyclohexyl)Piperazine Inhibitor Cis-22A, PDB code: 7k4b:

Calcium binding site 1 out of 1 in the Cryo-Em Structure of Human TRPV6 in Complex with (4- Phenylcyclohexyl)Piperazine Inhibitor Cis-22A


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 1 of Cryo-Em Structure of Human TRPV6 in Complex with (4- Phenylcyclohexyl)Piperazine Inhibitor Cis-22A within 5.0Å range: probe atom residue distance (Å) B Occ A:Ca717 b:31.4 occ:1.00 OD1 D:ASP542 2.9 56.3 1.0 OD1 A:ASP542 3.0 58.9 1.0 OD1 B:ASP542 3.1 56.5 1.0 OD1 C:ASP542 3.1 56.3 1.0 CG D:ASP542 3.9 56.3 1.0 CG A:ASP542 4.1 58.9 1.0 CG B:ASP542 4.1 56.5 1.0 CB D:ASP542 4.1 56.3 1.0 CG C:ASP542 4.1 56.3 1.0 CA D:ASP542 4.2 56.3 1.0 CB A:ASP542 4.4 58.9 1.0 CB B:ASP542 4.4 56.5 1.0 CB C:ASP542 4.4 56.3 1.0 CA A:ASP542 4.4 58.9 1.0 CA B:ASP542 4.5 56.5 1.0 CA C:ASP542 4.5 56.3 1.0 N D:ASP542 4.8 56.3 1.0

R.Bhardwaj, S.Lindinger, A.Neuberger, K.D.Nadezhdin, A.K.Singh, M.R.Cunha, I.Derler, G.Gyimesi, J.L.Reymond, M.A.Hediger, C.Romanin, A.I.Sobolevsky. Inactivation-Mimicking Block of the Epithelial Calcium Channel TRPV6. Sci Adv V. 6 2020.
ISSN: ESSN 2375-2548
PubMed: 33246965
DOI: 10.1126/SCIADV.ABE1508