Calcium in PDB 7kox: Alpha-7 Nicotinic Acetylcholine Receptor Bound to Epibatidine and Pnu- 120596 in the Activated State

The structure of Alpha-7 Nicotinic Acetylcholine Receptor Bound to Epibatidine and Pnu- 120596 in the Activated State also contains other interesting chemical elements:

Chlorine

(Cl)

5 atoms

The binding sites of Calcium atom in the Alpha-7 Nicotinic Acetylcholine Receptor Bound to Epibatidine and Pnu- 120596 in the Activated State (pdb code 7kox). This binding sites where shown within 5.0 Angstroms radius around Calcium atom.
In total 5 binding sites of Calcium where determined in the Alpha-7 Nicotinic Acetylcholine Receptor Bound to Epibatidine and Pnu- 120596 in the Activated State, PDB code: 7kox:
Jump to Calcium binding site number: 1; 2; 3; 4; 5;

Calcium binding site 1 out of 5 in the Alpha-7 Nicotinic Acetylcholine Receptor Bound to Epibatidine and Pnu- 120596 in the Activated State


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 1 of Alpha-7 Nicotinic Acetylcholine Receptor Bound to Epibatidine and Pnu- 120596 in the Activated State within 5.0Å range: probe atom residue distance (Å) B Occ A:Ca504 b:89.4 occ:1.00 O A:VAL42 2.7 89.9 1.0 OE1 A:GLU44 2.7 100.7 1.0 OE2 A:GLU44 3.3 100.7 1.0 CD A:GLU44 3.4 100.7 1.0 HA A:ASP43 3.7 94.6 1.0 C A:VAL42 3.8 89.9 1.0 H A:GLU44 3.8 100.7 1.0 OD1 A:ASP41 4.0 85.0 1.0 H A:VAL42 4.0 89.9 1.0 HB A:VAL42 4.3 89.9 1.0 CA A:ASP43 4.5 94.6 1.0 N A:ASP43 4.5 94.6 1.0 N A:GLU44 4.6 100.7 1.0 OE1 A:GLU172 4.6 103.4 1.0 N A:VAL42 4.7 89.9 1.0 CA A:VAL42 4.7 89.9 1.0 CG A:GLU44 4.8 100.7 1.0 HE1 A:TRP173 4.9 97.0 1.0 HG3 A:GLU44 4.9 100.7 1.0 CB A:VAL42 5.0 89.9 1.0

Calcium binding site 2 out of 5 in the Alpha-7 Nicotinic Acetylcholine Receptor Bound to Epibatidine and Pnu- 120596 in the Activated State


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 2 of Alpha-7 Nicotinic Acetylcholine Receptor Bound to Epibatidine and Pnu- 120596 in the Activated State within 5.0Å range: probe atom residue distance (Å) B Occ B:Ca504 b:95.2 occ:1.00 O B:VAL42 2.7 90.1 1.0 OE1 B:GLU44 2.7 101.0 1.0 OE2 B:GLU44 3.3 101.0 1.0 CD B:GLU44 3.3 101.0 1.0 HA B:ASP43 3.7 94.8 1.0 C B:VAL42 3.8 90.1 1.0 H B:GLU44 3.8 101.0 1.0 OD1 B:ASP41 4.0 85.5 1.0 H B:VAL42 4.0 90.1 1.0 HB B:VAL42 4.3 90.1 1.0 CA B:ASP43 4.5 94.8 1.0 N B:ASP43 4.5 94.8 1.0 N B:GLU44 4.6 101.0 1.0 OE1 B:GLU172 4.6 102.7 1.0 CA B:VAL42 4.7 90.1 1.0 N B:VAL42 4.7 90.1 1.0 CG B:GLU44 4.7 101.0 1.0 HE1 B:TRP173 4.9 96.6 1.0 HG3 B:GLU44 4.9 101.0 1.0 CB B:VAL42 4.9 90.1 1.0

Calcium binding site 3 out of 5 in the Alpha-7 Nicotinic Acetylcholine Receptor Bound to Epibatidine and Pnu- 120596 in the Activated State


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 3 of Alpha-7 Nicotinic Acetylcholine Receptor Bound to Epibatidine and Pnu- 120596 in the Activated State within 5.0Å range: probe atom residue distance (Å) B Occ C:Ca504 b:92.2 occ:1.00 O C:VAL42 2.7 90.3 1.0 OE1 C:GLU44 2.9 101.3 1.0 OE2 C:GLU44 3.5 101.3 1.0 CD C:GLU44 3.6 101.3 1.0 HA C:ASP43 3.7 95.4 1.0 C C:VAL42 3.7 90.3 1.0 OD1 C:ASP41 3.7 85.6 1.0 H C:VAL42 3.9 90.3 1.0 H C:GLU44 3.9 101.3 1.0 HB C:VAL42 4.2 90.3 1.0 N C:ASP43 4.5 95.4 1.0 CA C:ASP43 4.5 95.4 1.0 N C:VAL42 4.6 90.3 1.0 OE1 C:GLU172 4.6 103.5 1.0 CA C:VAL42 4.6 90.3 1.0 N C:GLU44 4.7 101.3 1.0 HE1 C:TRP173 4.8 97.0 1.0 CG C:ASP41 4.9 85.6 1.0 CB C:VAL42 4.9 90.3 1.0 CG C:GLU44 4.9 101.3 1.0

Calcium binding site 4 out of 5 in the Alpha-7 Nicotinic Acetylcholine Receptor Bound to Epibatidine and Pnu- 120596 in the Activated State


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 4 of Alpha-7 Nicotinic Acetylcholine Receptor Bound to Epibatidine and Pnu- 120596 in the Activated State within 5.0Å range: probe atom residue distance (Å) B Occ D:Ca504 b:89.0 occ:1.00 O D:VAL42 2.7 90.4 1.0 OE1 D:GLU44 2.7 100.9 1.0 OE2 D:GLU44 3.3 100.9 1.0 CD D:GLU44 3.3 100.9 1.0 HA D:ASP43 3.7 95.2 1.0 C D:VAL42 3.7 90.4 1.0 H D:GLU44 3.8 100.9 1.0 OD1 D:ASP41 4.0 86.1 1.0 H D:VAL42 4.0 90.4 1.0 HB D:VAL42 4.2 90.4 1.0 CA D:ASP43 4.5 95.2 1.0 N D:ASP43 4.5 95.2 1.0 OE1 D:GLU172 4.6 103.3 1.0 N D:GLU44 4.6 100.9 1.0 N D:VAL42 4.7 90.4 1.0 CA D:VAL42 4.7 90.4 1.0 CG D:GLU44 4.8 100.9 1.0 HE1 D:TRP173 4.8 96.8 1.0 HG3 D:GLU44 4.9 100.9 1.0 CB D:VAL42 4.9 90.4 1.0

Calcium binding site 5 out of 5 in the Alpha-7 Nicotinic Acetylcholine Receptor Bound to Epibatidine and Pnu- 120596 in the Activated State


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 5 of Alpha-7 Nicotinic Acetylcholine Receptor Bound to Epibatidine and Pnu- 120596 in the Activated State within 5.0Å range: probe atom residue distance (Å) B Occ E:Ca504 b:91.1 occ:1.00 O E:VAL42 2.7 89.8 1.0 OE1 E:GLU44 2.7 100.9 1.0 OE2 E:GLU44 3.3 100.9 1.0 CD E:GLU44 3.3 100.9 1.0 HA E:ASP43 3.7 95.2 1.0 C E:VAL42 3.7 89.8 1.0 H E:GLU44 3.8 100.9 1.0 OD1 E:ASP41 4.0 84.6 1.0 H E:VAL42 4.0 89.8 1.0 HB E:VAL42 4.2 89.8 1.0 CA E:ASP43 4.5 95.2 1.0 N E:ASP43 4.5 95.2 1.0 N E:GLU44 4.6 100.9 1.0 OE1 E:GLU172 4.6 102.7 1.0 CA E:VAL42 4.7 89.8 1.0 N E:VAL42 4.7 89.8 1.0 CG E:GLU44 4.7 100.9 1.0 HE1 E:TRP173 4.8 96.2 1.0 HG3 E:GLU44 4.9 100.9 1.0 CB E:VAL42 4.9 89.8 1.0

C.M.Noviello, R.E.Hibbs. Structure and Gating Mechanism of the Alpha-7 Nicotinic Acetylcholine Receptor Cell(Cambridge,Mass.) 2021.
ISSN: ISSN 0092-8674
DOI: 10.1016/J.CELL.2021.02.049