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Calcium in PDB 7kqn: Ternary Complex of Tert (Telomerase Reverse Transcriptase) with Rna Template, Dna Primer, An Incoming Dgtp and A Downstream Hybrid Duplex
Enzymatic activity of Ternary Complex of Tert (Telomerase Reverse Transcriptase) with Rna Template, Dna Primer, An Incoming Dgtp and A Downstream Hybrid Duplex
All present enzymatic activity of Ternary Complex of Tert (Telomerase Reverse Transcriptase) with Rna Template, Dna Primer, An Incoming Dgtp and A Downstream Hybrid Duplex:
2.7.7.49;
2.7.7.49;
Protein crystallography data
The structure of Ternary Complex of Tert (Telomerase Reverse Transcriptase) with Rna Template, Dna Primer, An Incoming Dgtp and A Downstream Hybrid Duplex, PDB code: 7kqn
was solved by
W.S.Choi,
P.J.Weng,
W.Yang,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
| Resolution Low / High (Å) | 29.65 / 2.02 |
| Space group | P 1 21 1 |
| Cell size a, b, c (Å), α, β, γ (°) | 71.86, 164.04, 95.36, 90, 111.91, 90 |
| R / Rfree (%) | 16.8 / 18.8 |
Calcium Binding Sites:
The binding sites of Calcium atom in the Ternary Complex of Tert (Telomerase Reverse Transcriptase) with Rna Template, Dna Primer, An Incoming Dgtp and A Downstream Hybrid Duplex
(pdb code 7kqn). This binding sites where shown within
5.0 Angstroms radius around Calcium atom.
In total 2 binding sites of Calcium where determined in the Ternary Complex of Tert (Telomerase Reverse Transcriptase) with Rna Template, Dna Primer, An Incoming Dgtp and A Downstream Hybrid Duplex, PDB code: 7kqn:
Jump to Calcium binding site number: 1; 2;
In total 2 binding sites of Calcium where determined in the Ternary Complex of Tert (Telomerase Reverse Transcriptase) with Rna Template, Dna Primer, An Incoming Dgtp and A Downstream Hybrid Duplex, PDB code: 7kqn:
Jump to Calcium binding site number: 1; 2;
Calcium binding site 1 out of 2 in 7kqn
Go back to
Calcium Binding Sites List in 7kqn
Calcium binding site 1 out
of 2 in the Ternary Complex of Tert (Telomerase Reverse Transcriptase) with Rna Template, Dna Primer, An Incoming Dgtp and A Downstream Hybrid Duplex
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Calcium with other atoms in the Ca binding
site number 1 of Ternary Complex of Tert (Telomerase Reverse Transcriptase) with Rna Template, Dna Primer, An Incoming Dgtp and A Downstream Hybrid Duplex within 5.0Å range:
|
Calcium binding site 2 out of 2 in 7kqn
Go back to
Calcium Binding Sites List in 7kqn
Calcium binding site 2 out
of 2 in the Ternary Complex of Tert (Telomerase Reverse Transcriptase) with Rna Template, Dna Primer, An Incoming Dgtp and A Downstream Hybrid Duplex
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Calcium with other atoms in the Ca binding
site number 2 of Ternary Complex of Tert (Telomerase Reverse Transcriptase) with Rna Template, Dna Primer, An Incoming Dgtp and A Downstream Hybrid Duplex within 5.0Å range:
|
Reference:
W.S.Choi,
P.J.Weng,
W.Yang.
Flexibility of Telomerase in Binding the Rna Template and Dna Telomeric Repeat. Proc.Natl.Acad.Sci.Usa V. 119 2022.
ISSN: ESSN 1091-6490
PubMed: 34969861
DOI: 10.1073/PNAS.2116159118
Page generated: Fri Jul 19 01:22:59 2024
ISSN: ESSN 1091-6490
PubMed: 34969861
DOI: 10.1073/PNAS.2116159118
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