Calcium in PDB 7kxr: Protective Antigen Pore Translocating Lethal Factor N-Terminal Domain

All present enzymatic activity of Protective Antigen Pore Translocating Lethal Factor N-Terminal Domain:
3.4.24.83;

Pages:

>>> Page 1 <<< Page 2, Binding sites: 11 - 14;

Binding sites:

The binding sites of Calcium atom in the Protective Antigen Pore Translocating Lethal Factor N-Terminal Domain (pdb code 7kxr). This binding sites where shown within 5.0 Angstroms radius around Calcium atom.
In total 14 binding sites of Calcium where determined in the Protective Antigen Pore Translocating Lethal Factor N-Terminal Domain, PDB code: 7kxr:
Jump to Calcium binding site number: 1; 2; 3; 4; 5; 6; 7; 8; 9; 10;

Calcium binding site 1 out of 14 in the Protective Antigen Pore Translocating Lethal Factor N-Terminal Domain


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 1 of Protective Antigen Pore Translocating Lethal Factor N-Terminal Domain within 5.0Å range: probe atom residue distance (Å) B Occ A:Ca801 b:220.7 occ:1.00 O A:ILE183 2.1 181.5 1.0 OD2 A:ASP179 2.2 197.9 1.0 OD1 A:ASP179 2.3 197.9 1.0 OD1 A:ASP181 2.3 195.0 1.0 CG A:ASP179 2.5 197.9 1.0 CG A:ASP181 3.2 195.0 1.0 C A:ILE183 3.3 181.5 1.0 OD2 A:ASP181 3.3 195.0 1.0 CG2 A:ILE183 3.6 181.5 1.0 OD1 A:ASP185 3.7 198.7 1.0 CA A:CA802 3.7 187.7 1.0 O A:PRO184 3.9 176.4 1.0 CB A:ASP179 4.0 197.9 1.0 C A:PRO184 4.1 176.4 1.0 CA A:ILE183 4.1 181.5 1.0 CB A:ILE183 4.2 181.5 1.0 N A:ILE183 4.2 181.5 1.0 N A:PRO184 4.3 176.4 1.0 O A:SER222 4.4 179.2 1.0 CA A:PRO184 4.4 176.4 1.0 CB A:ASP177 4.4 203.9 1.0 CG1 A:ILE183 4.4 181.5 1.0 O A:PRO223 4.5 187.6 1.0 N A:ASP185 4.6 198.7 1.0 CB A:ASP181 4.6 195.0 1.0 N A:ASP181 4.7 195.0 1.0 CA A:ASP185 4.7 198.7 1.0 CA A:PRO223 4.7 187.6 1.0 CA A:ASP177 4.8 203.9 1.0 N A:ASP179 4.8 197.9 1.0 CA A:ASP179 4.8 197.9 1.0 CB A:GLU188 4.8 196.7 1.0 CG A:ASP185 4.8 198.7 1.0 C A:PRO223 4.8 187.6 1.0 N A:ASN180 5.0 192.5 1.0

Calcium binding site 2 out of 14 in the Protective Antigen Pore Translocating Lethal Factor N-Terminal Domain


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 2 of Protective Antigen Pore Translocating Lethal Factor N-Terminal Domain within 5.0Å range: probe atom residue distance (Å) B Occ A:Ca802 b:187.7 occ:1.00 O A:LYS225 2.2 176.3 1.0 O A:SER222 2.3 179.2 1.0 OD2 A:ASP179 2.3 197.9 1.0 OD2 A:ASP235 2.3 186.5 1.0 OD2 A:ASP181 2.4 195.0 1.0 CG A:ASP179 3.2 197.9 1.0 C A:LYS225 3.3 176.3 1.0 CG A:ASP181 3.5 195.0 1.0 C A:SER222 3.5 179.2 1.0 CG A:ASP235 3.6 186.5 1.0 CB A:ASP179 3.6 197.9 1.0 CA A:CA801 3.7 220.7 1.0 OG1 A:THR228 3.9 168.9 1.0 OD1 A:ASP181 3.9 195.0 1.0 N A:LYS225 4.1 176.3 1.0 OG A:SER221 4.1 184.2 1.0 N A:TRP226 4.2 174.6 1.0 CA A:LYS225 4.2 176.3 1.0 N A:SER222 4.3 179.2 1.0 OD1 A:ASP179 4.3 197.9 1.0 CA A:SER222 4.3 179.2 1.0 CB A:ASP235 4.4 186.5 1.0 CA A:TRP226 4.4 174.6 1.0 N A:PRO223 4.4 187.6 1.0 OD1 A:ASP235 4.5 186.5 1.0 CA A:PRO223 4.5 187.6 1.0 C A:TRP226 4.5 174.6 1.0 C A:PRO223 4.5 187.6 1.0 O A:TRP226 4.5 174.6 1.0 CB A:SER222 4.6 179.2 1.0 CB A:ASP181 4.7 195.0 1.0 N A:GLU224 4.7 194.9 1.0 CB A:LYS225 4.7 176.3 1.0 CB A:SER221 4.8 184.2 1.0 O A:PRO223 4.9 187.6 1.0 C A:GLU224 5.0 194.9 1.0

Calcium binding site 3 out of 14 in the Protective Antigen Pore Translocating Lethal Factor N-Terminal Domain


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 3 of Protective Antigen Pore Translocating Lethal Factor N-Terminal Domain within 5.0Å range: probe atom residue distance (Å) B Occ B:Ca801 b:215.5 occ:1.00 O B:ILE183 2.1 195.6 1.0 OD2 B:ASP179 2.2 189.6 1.0 OD1 B:ASP179 2.3 189.6 1.0 OD1 B:ASP181 2.3 202.6 1.0 CG B:ASP179 2.5 189.6 1.0 CG B:ASP181 3.2 202.6 1.0 C B:ILE183 3.3 195.6 1.0 OD2 B:ASP181 3.3 202.6 1.0 CG2 B:ILE183 3.6 195.6 1.0 OD1 B:ASP185 3.7 193.6 1.0 CA B:CA802 3.7 193.4 1.0 O B:PRO184 3.9 184.5 1.0 CB B:ASP179 4.0 189.6 1.0 C B:PRO184 4.1 184.5 1.0 CA B:ILE183 4.1 195.6 1.0 CB B:ILE183 4.2 195.6 1.0 N B:ILE183 4.2 195.6 1.0 N B:PRO184 4.3 184.5 1.0 O B:SER222 4.4 181.1 1.0 CA B:PRO184 4.4 184.5 1.0 CB B:ASP177 4.4 197.2 1.0 CG1 B:ILE183 4.4 195.6 1.0 O B:PRO223 4.5 183.9 1.0 N B:ASP185 4.6 193.6 1.0 CB B:ASP181 4.6 202.6 1.0 N B:ASP181 4.7 202.6 1.0 CA B:ASP185 4.7 193.6 1.0 CA B:PRO223 4.7 183.9 1.0 CA B:ASP177 4.8 197.2 1.0 N B:ASP179 4.8 189.6 1.0 CA B:ASP179 4.8 189.6 1.0 CB B:GLU188 4.8 204.9 1.0 CG B:ASP185 4.8 193.6 1.0 C B:PRO223 4.8 183.9 1.0 N B:ASN180 5.0 185.5 1.0

Calcium binding site 4 out of 14 in the Protective Antigen Pore Translocating Lethal Factor N-Terminal Domain


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 4 of Protective Antigen Pore Translocating Lethal Factor N-Terminal Domain within 5.0Å range: probe atom residue distance (Å) B Occ B:Ca802 b:193.4 occ:1.00 O B:LYS225 2.2 183.1 1.0 O B:SER222 2.3 181.1 1.0 OD2 B:ASP179 2.3 189.6 1.0 OD2 B:ASP235 2.3 202.7 1.0 OD2 B:ASP181 2.4 202.6 1.0 CG B:ASP179 3.2 189.6 1.0 C B:LYS225 3.3 183.1 1.0 CG B:ASP181 3.5 202.6 1.0 C B:SER222 3.5 181.1 1.0 CG B:ASP235 3.6 202.7 1.0 CB B:ASP179 3.6 189.6 1.0 CA B:CA801 3.7 215.5 1.0 OG1 B:THR228 3.9 194.0 1.0 OD1 B:ASP181 3.9 202.6 1.0 N B:LYS225 4.1 183.1 1.0 OG B:SER221 4.1 201.2 1.0 N B:TRP226 4.2 176.4 1.0 CA B:LYS225 4.2 183.1 1.0 N B:SER222 4.3 181.1 1.0 OD1 B:ASP179 4.3 189.6 1.0 CA B:SER222 4.3 181.1 1.0 CB B:ASP235 4.4 202.7 1.0 CA B:TRP226 4.4 176.4 1.0 N B:PRO223 4.4 183.9 1.0 OD1 B:ASP235 4.5 202.7 1.0 CA B:PRO223 4.5 183.9 1.0 C B:TRP226 4.5 176.4 1.0 C B:PRO223 4.5 183.9 1.0 O B:TRP226 4.5 176.4 1.0 CB B:SER222 4.6 181.1 1.0 CB B:ASP181 4.7 202.6 1.0 N B:GLU224 4.7 196.8 1.0 CB B:LYS225 4.7 183.1 1.0 CB B:SER221 4.8 201.2 1.0 O B:PRO223 4.9 183.9 1.0 C B:GLU224 5.0 196.8 1.0

Calcium binding site 5 out of 14 in the Protective Antigen Pore Translocating Lethal Factor N-Terminal Domain


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 5 of Protective Antigen Pore Translocating Lethal Factor N-Terminal Domain within 5.0Å range: probe atom residue distance (Å) B Occ C:Ca801 b:228.5 occ:1.00 O C:ILE183 2.1 191.6 1.0 OD2 C:ASP179 2.2 202.1 1.0 OD1 C:ASP179 2.3 202.1 1.0 OD1 C:ASP181 2.3 198.6 1.0 CG C:ASP179 2.5 202.1 1.0 CG C:ASP181 3.2 198.6 1.0 C C:ILE183 3.3 191.6 1.0 OD2 C:ASP181 3.3 198.6 1.0 CG2 C:ILE183 3.6 191.6 1.0 OD1 C:ASP185 3.7 198.8 1.0 CA C:CA802 3.7 204.5 1.0 O C:PRO184 3.9 185.7 1.0 CB C:ASP179 4.0 202.1 1.0 C C:PRO184 4.1 185.7 1.0 CA C:ILE183 4.1 191.6 1.0 CB C:ILE183 4.2 191.6 1.0 N C:ILE183 4.2 191.6 1.0 N C:PRO184 4.3 185.7 1.0 O C:SER222 4.4 188.3 1.0 CA C:PRO184 4.4 185.7 1.0 CB C:ASP177 4.4 207.5 1.0 CG1 C:ILE183 4.4 191.6 1.0 O C:PRO223 4.5 183.5 1.0 N C:ASP185 4.6 198.8 1.0 CB C:ASP181 4.6 198.6 1.0 N C:ASP181 4.7 198.6 1.0 CA C:ASP185 4.7 198.8 1.0 CA C:PRO223 4.7 183.5 1.0 CA C:ASP177 4.8 207.5 1.0 N C:ASP179 4.8 202.1 1.0 CA C:ASP179 4.8 202.1 1.0 CB C:GLU188 4.8 196.0 1.0 CG C:ASP185 4.8 198.8 1.0 C C:PRO223 4.8 183.5 1.0

Calcium binding site 6 out of 14 in the Protective Antigen Pore Translocating Lethal Factor N-Terminal Domain


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 6 of Protective Antigen Pore Translocating Lethal Factor N-Terminal Domain within 5.0Å range: probe atom residue distance (Å) B Occ C:Ca802 b:204.5 occ:1.00 O C:LYS225 2.2 184.7 1.0 O C:SER222 2.3 188.3 1.0 OD2 C:ASP179 2.3 202.1 1.0 OD2 C:ASP235 2.3 206.5 1.0 OD2 C:ASP181 2.4 198.6 1.0 CG C:ASP179 3.2 202.1 1.0 C C:LYS225 3.3 184.7 1.0 CG C:ASP181 3.5 198.6 1.0 C C:SER222 3.5 188.3 1.0 CG C:ASP235 3.6 206.5 1.0 CB C:ASP179 3.6 202.1 1.0 CA C:CA801 3.7 228.5 1.0 OG1 C:THR228 3.9 191.6 1.0 OD1 C:ASP181 3.9 198.6 1.0 N C:LYS225 4.1 184.7 1.0 OG C:SER221 4.1 195.9 1.0 N C:TRP226 4.2 181.3 1.0 CA C:LYS225 4.2 184.7 1.0 N C:SER222 4.3 188.3 1.0 OD1 C:ASP179 4.3 202.1 1.0 CA C:SER222 4.3 188.3 1.0 CB C:ASP235 4.4 206.5 1.0 CA C:TRP226 4.4 181.3 1.0 N C:PRO223 4.4 183.5 1.0 OD1 C:ASP235 4.5 206.5 1.0 CA C:PRO223 4.5 183.5 1.0 C C:TRP226 4.5 181.3 1.0 C C:PRO223 4.5 183.5 1.0 O C:TRP226 4.5 181.3 1.0 CB C:SER222 4.6 188.3 1.0 CB C:ASP181 4.7 198.6 1.0 N C:GLU224 4.7 191.9 1.0 CB C:LYS225 4.7 184.7 1.0 CB C:SER221 4.8 195.9 1.0 O C:PRO223 4.9 183.5 1.0 C C:GLU224 5.0 191.9 1.0

Calcium binding site 7 out of 14 in the Protective Antigen Pore Translocating Lethal Factor N-Terminal Domain


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 7 of Protective Antigen Pore Translocating Lethal Factor N-Terminal Domain within 5.0Å range: probe atom residue distance (Å) B Occ D:Ca801 b:220.4 occ:1.00 O D:ILE183 2.1 182.0 1.0 OD2 D:ASP179 2.2 187.8 1.0 OD1 D:ASP179 2.3 187.8 1.0 OD1 D:ASP181 2.3 189.0 1.0 CG D:ASP179 2.5 187.8 1.0 CG D:ASP181 3.2 189.0 1.0 C D:ILE183 3.3 182.0 1.0 OD2 D:ASP181 3.3 189.0 1.0 CG2 D:ILE183 3.6 182.0 1.0 OD1 D:ASP185 3.7 193.5 1.0 CA D:CA802 3.7 175.1 1.0 O D:PRO184 3.9 180.6 1.0 CB D:ASP179 4.0 187.8 1.0 C D:PRO184 4.1 180.6 1.0 CA D:ILE183 4.1 182.0 1.0 CB D:ILE183 4.2 182.0 1.0 N D:ILE183 4.2 182.0 1.0 N D:PRO184 4.3 180.6 1.0 O D:SER222 4.4 181.0 1.0 CA D:PRO184 4.4 180.6 1.0 CB D:ASP177 4.4 188.4 1.0 CG1 D:ILE183 4.4 182.0 1.0 O D:PRO223 4.5 180.5 1.0 N D:ASP185 4.6 193.5 1.0 CB D:ASP181 4.6 189.0 1.0 N D:ASP181 4.7 189.0 1.0 CA D:ASP185 4.7 193.5 1.0 CA D:PRO223 4.7 180.5 1.0 CA D:ASP177 4.8 188.4 1.0 N D:ASP179 4.8 187.8 1.0 CA D:ASP179 4.8 187.8 1.0 CB D:GLU188 4.8 188.5 1.0 CG D:ASP185 4.8 193.5 1.0 C D:PRO223 4.8 180.5 1.0 N D:ASN180 5.0 193.6 1.0

Calcium binding site 8 out of 14 in the Protective Antigen Pore Translocating Lethal Factor N-Terminal Domain


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 8 of Protective Antigen Pore Translocating Lethal Factor N-Terminal Domain within 5.0Å range: probe atom residue distance (Å) B Occ D:Ca802 b:175.1 occ:1.00 O D:LYS225 2.2 173.1 1.0 O D:SER222 2.3 181.0 1.0 OD2 D:ASP179 2.3 187.8 1.0 OD2 D:ASP235 2.3 187.1 1.0 OD2 D:ASP181 2.4 189.0 1.0 CG D:ASP179 3.2 187.8 1.0 C D:LYS225 3.3 173.1 1.0 CG D:ASP181 3.5 189.0 1.0 C D:SER222 3.5 181.0 1.0 CG D:ASP235 3.6 187.1 1.0 CB D:ASP179 3.6 187.8 1.0 CA D:CA801 3.7 220.4 1.0 OG1 D:THR228 3.9 177.7 1.0 OD1 D:ASP181 3.9 189.0 1.0 N D:LYS225 4.1 173.1 1.0 OG D:SER221 4.1 186.3 1.0 N D:TRP226 4.2 174.8 1.0 CA D:LYS225 4.2 173.1 1.0 N D:SER222 4.3 181.0 1.0 OD1 D:ASP179 4.3 187.8 1.0 CA D:SER222 4.3 181.0 1.0 CB D:ASP235 4.4 187.1 1.0 CA D:TRP226 4.4 174.8 1.0 N D:PRO223 4.4 180.5 1.0 OD1 D:ASP235 4.5 187.1 1.0 CA D:PRO223 4.5 180.5 1.0 C D:TRP226 4.5 174.8 1.0 C D:PRO223 4.5 180.5 1.0 O D:TRP226 4.5 174.8 1.0 CB D:SER222 4.6 181.0 1.0 CB D:ASP181 4.7 189.0 1.0 N D:GLU224 4.7 184.2 1.0 CB D:LYS225 4.7 173.1 1.0 CB D:SER221 4.8 186.3 1.0 O D:PRO223 4.9 180.5 1.0 C D:GLU224 5.0 184.2 1.0

Calcium binding site 9 out of 14 in the Protective Antigen Pore Translocating Lethal Factor N-Terminal Domain


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 9 of Protective Antigen Pore Translocating Lethal Factor N-Terminal Domain within 5.0Å range: probe atom residue distance (Å) B Occ E:Ca801 b:174.8 occ:1.00 O E:ILE183 2.1 166.1 1.0 OD2 E:ASP179 2.2 173.9 1.0 OD1 E:ASP179 2.3 173.9 1.0 OD1 E:ASP181 2.3 173.8 1.0 CG E:ASP179 2.5 173.9 1.0 CG E:ASP181 3.2 173.8 1.0 C E:ILE183 3.3 166.1 1.0 OD2 E:ASP181 3.3 173.8 1.0 CG2 E:ILE183 3.6 166.1 1.0 OD1 E:ASP185 3.7 186.2 1.0 CA E:CA802 3.7 165.5 1.0 O E:PRO184 3.9 162.1 1.0 CB E:ASP179 4.0 173.9 1.0 C E:PRO184 4.1 162.1 1.0 CA E:ILE183 4.1 166.1 1.0 CB E:ILE183 4.2 166.1 1.0 N E:ILE183 4.2 166.1 1.0 N E:PRO184 4.3 162.1 1.0 O E:SER222 4.4 165.7 1.0 CA E:PRO184 4.4 162.1 1.0 CB E:ASP177 4.4 177.2 1.0 CG1 E:ILE183 4.4 166.1 1.0 O E:PRO223 4.5 168.3 1.0 N E:ASP185 4.6 186.2 1.0 CB E:ASP181 4.6 173.8 1.0 N E:ASP181 4.7 173.8 1.0 CA E:ASP185 4.7 186.2 1.0 CA E:PRO223 4.7 168.3 1.0 CA E:ASP177 4.8 177.2 1.0 N E:ASP179 4.8 173.9 1.0 CA E:ASP179 4.8 173.9 1.0 CB E:GLU188 4.8 174.1 1.0 CG E:ASP185 4.8 186.2 1.0 C E:PRO223 4.8 168.3 1.0 N E:ASN180 5.0 173.5 1.0

Calcium binding site 10 out of 14 in the Protective Antigen Pore Translocating Lethal Factor N-Terminal Domain


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 10 of Protective Antigen Pore Translocating Lethal Factor N-Terminal Domain within 5.0Å range: probe atom residue distance (Å) B Occ E:Ca802 b:165.5 occ:1.00 O E:LYS225 2.2 167.9 1.0 O E:SER222 2.3 165.7 1.0 OD2 E:ASP179 2.3 173.9 1.0 OD2 E:ASP235 2.3 180.5 1.0 OD2 E:ASP181 2.4 173.8 1.0 CG E:ASP179 3.2 173.9 1.0 C E:LYS225 3.3 167.9 1.0 CG E:ASP181 3.5 173.8 1.0 C E:SER222 3.5 165.7 1.0 CG E:ASP235 3.6 180.5 1.0 CB E:ASP179 3.6 173.9 1.0 CA E:CA801 3.7 174.8 1.0 OG1 E:THR228 3.9 173.4 1.0 OD1 E:ASP181 3.9 173.8 1.0 N E:LYS225 4.1 167.9 1.0 OG E:SER221 4.1 176.5 1.0 N E:TRP226 4.2 164.7 1.0 CA E:LYS225 4.2 167.9 1.0 N E:SER222 4.3 165.7 1.0 OD1 E:ASP179 4.3 173.9 1.0 CA E:SER222 4.3 165.7 1.0 CB E:ASP235 4.4 180.5 1.0 CA E:TRP226 4.4 164.7 1.0 N E:PRO223 4.4 168.3 1.0 OD1 E:ASP235 4.5 180.5 1.0 C E:TRP226 4.5 164.7 1.0 CA E:PRO223 4.5 168.3 1.0 C E:PRO223 4.5 168.3 1.0 O E:TRP226 4.5 164.7 1.0 CB E:SER222 4.6 165.7 1.0 CB E:ASP181 4.7 173.8 1.0 N E:GLU224 4.7 178.4 1.0 CB E:LYS225 4.7 167.9 1.0 CB E:SER221 4.8 176.5 1.0 O E:PRO223 4.9 168.3 1.0 C E:GLU224 5.0 178.4 1.0

A.J.Machen, M.T.Fisher, B.D.Freudenthal. Anthrax Toxin Translocation Complex Reveals Insight Into the Lethal Factor Unfolding and Refolding Mechanism. Sci Rep V. 11 13038 2021.
ISSN: ESSN 2045-2322
PubMed: 34158520
DOI: 10.1038/S41598-021-91596-3