Calcium in PDB 7l64: C-Type Carbohydrate-Recognition Domain 4 of the Mannose Receptor Complexed with Lewis-A

The structure of C-Type Carbohydrate-Recognition Domain 4 of the Mannose Receptor Complexed with Lewis-A, PDB code: 7l64 was solved by W.I.Weis, H.Feinberg, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	30.47 / 1.35
Space group	P 1 21 1
Cell size a, b, c (Å), α, β, γ (°)	33.053, 57.18, 34.383, 90, 112.81, 90
R / Rfree (%)	16.5 / 19.8

The binding sites of Calcium atom in the C-Type Carbohydrate-Recognition Domain 4 of the Mannose Receptor Complexed with Lewis-A (pdb code 7l64). This binding sites where shown within 5.0 Angstroms radius around Calcium atom.
In total 2 binding sites of Calcium where determined in the C-Type Carbohydrate-Recognition Domain 4 of the Mannose Receptor Complexed with Lewis-A, PDB code: 7l64:
Jump to Calcium binding site number: 1; 2;

Calcium binding site 1 out of 2 in the C-Type Carbohydrate-Recognition Domain 4 of the Mannose Receptor Complexed with Lewis-A


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 1 of C-Type Carbohydrate-Recognition Domain 4 of the Mannose Receptor Complexed with Lewis-A within 5.0Å range: probe atom residue distance (Å) B Occ A:Ca800 b:13.5 occ:1.00 OD1 A:ASP748 2.3 14.0 1.0 OD1 A:ASN727 2.4 15.9 1.0 OD1 A:ASN747 2.4 13.6 1.0 OE1 A:GLU733 2.5 15.6 1.0 O A:ASP748 2.5 13.0 1.0 O4 B:FUC3 2.5 14.3 1.0 OE1 A:GLU725 2.5 15.5 1.0 O3 B:FUC3 2.5 14.2 1.0 CG A:ASP748 3.3 14.0 1.0 C4 B:FUC3 3.3 15.0 1.0 CG A:ASN727 3.4 15.7 1.0 CD A:GLU725 3.4 15.3 1.0 CG A:ASN747 3.4 14.3 1.0 CD A:GLU733 3.4 14.8 1.0 C3 B:FUC3 3.4 15.4 1.0 C A:ASP748 3.5 12.4 1.0 OE2 A:GLU725 3.7 18.4 1.0 OE2 A:GLU733 3.8 15.3 1.0 N A:ASP748 3.8 12.0 1.0 ND2 A:ASN747 3.8 14.5 1.0 ND2 A:ASN727 3.9 18.0 1.0 CA A:ASP748 4.0 13.1 1.0 C2 B:FUC3 4.1 15.9 1.0 OD2 A:ASP748 4.1 15.6 1.0 N A:ASN727 4.2 17.2 1.0 CB A:ASP748 4.3 13.0 1.0 CB A:ASN727 4.5 16.7 1.0 CG A:GLU725 4.6 15.3 1.0 C A:ASN747 4.6 11.8 1.0 N A:ASN728 4.6 16.7 1.0 N A:ILE749 4.7 12.8 1.0 CG A:GLU733 4.7 15.2 1.0 CB A:ASN747 4.7 12.8 1.0 CA A:ASN727 4.7 17.3 1.0 N A:TYR729 4.7 16.6 1.0 C5 B:FUC3 4.8 16.6 1.0 CB A:TYR729 4.8 20.7 1.0 O2 B:FUC3 4.8 18.2 1.0 CB A:GLU733 4.9 14.9 1.0 CA A:ASN747 4.9 12.3 1.0 C A:ASN727 4.9 17.8 1.0

Calcium binding site 2 out of 2 in the C-Type Carbohydrate-Recognition Domain 4 of the Mannose Receptor Complexed with Lewis-A


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 2 of C-Type Carbohydrate-Recognition Domain 4 of the Mannose Receptor Complexed with Lewis-A within 5.0Å range: probe atom residue distance (Å) B Occ A:Ca801 b:25.7 occ:0.75 OD1 A:ASN673 2.3 28.6 1.0 O A:HOH913 2.3 29.4 1.0 O A:HOH902 2.4 44.4 1.0 OE1 A:GLU677 2.5 26.7 0.8 O A:SER671 2.6 21.4 1.0 OG A:SER671 2.6 21.6 1.0 OE1 A:GLU677 2.7 19.5 0.2 OE2 A:GLU677 2.7 29.3 0.8 CD A:GLU677 3.0 26.7 0.8 C A:SER671 3.3 18.5 1.0 CG A:ASN673 3.4 28.2 1.0 CD A:GLU677 3.4 19.2 0.2 OE2 A:GLU677 3.5 19.2 0.2 CB A:SER671 3.6 19.5 1.0 CA A:SER671 3.9 18.3 1.0 N A:ASN673 3.9 22.7 1.0 CB A:ASN673 4.0 26.3 1.0 N A:ILE672 4.1 18.8 1.0 O A:HOH1003 4.2 41.9 1.0 OE1 A:GLN760 4.3 23.6 1.0 N A:SER671 4.4 16.7 1.0 CA A:ILE672 4.4 19.6 1.0 ND2 A:ASN673 4.5 28.4 1.0 CG A:GLU677 4.5 24.4 0.8 C A:ILE672 4.5 20.7 1.0 CZ A:PHE642 4.6 25.8 1.0 CA A:ASN673 4.6 24.5 1.0 O A:HOH901 4.7 50.7 1.0 OD2 A:ASP712 4.7 25.0 1.0 CG A:GLU677 4.7 19.7 0.2 OG A:SER714 4.9 26.5 0.5 OG A:SER714 4.9 19.5 0.5 CE1 A:PHE642 5.0 25.1 1.0

H.Feinberg, S.A.F.Jegouzo, Y.Lasanajak, D.F.Smith, K.Drickamer, M.E.Taylor, W.I.Weis. Structural Analysis of Carbohydrate Binding By the Macrophage Mannose Receptor CD206 J.Biol.Chem. 2021.
ISSN: ESSN 1083-351X