Calcium in PDB 7l68: C-Type Carbohydrate-Recognition Domain 4 of the Mannose Receptor

The structure of C-Type Carbohydrate-Recognition Domain 4 of the Mannose Receptor, PDB code: 7l68 was solved by W.I.Weis, H.Feinberg, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	31.34 / 1.40
Space group	P 1 21 1
Cell size a, b, c (Å), α, β, γ (°)	31.623, 58.718, 62.383, 90, 97.66, 90
R / Rfree (%)	15.5 / 17.5

The binding sites of Calcium atom in the C-Type Carbohydrate-Recognition Domain 4 of the Mannose Receptor (pdb code 7l68). This binding sites where shown within 5.0 Angstroms radius around Calcium atom.
In total 2 binding sites of Calcium where determined in the C-Type Carbohydrate-Recognition Domain 4 of the Mannose Receptor, PDB code: 7l68:
Jump to Calcium binding site number: 1; 2;

Calcium binding site 1 out of 2 in the C-Type Carbohydrate-Recognition Domain 4 of the Mannose Receptor


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 1 of C-Type Carbohydrate-Recognition Domain 4 of the Mannose Receptor within 5.0Å range: probe atom residue distance (Å) B Occ A:Ca800 b:6.6 occ:1.00 OD1 A:ASN727 2.3 7.6 1.0 OD1 A:ASP748 2.3 7.3 1.0 O A:ASP748 2.4 6.9 1.0 OE1 A:GLU733 2.4 6.6 1.0 O A:HOH901 2.4 21.6 1.0 O A:HOH925 2.4 20.0 1.0 OE1 A:GLU725 2.4 16.6 1.0 OD1 A:ASN747 2.4 11.7 0.6 OE2 A:GLU725 3.1 21.3 1.0 CD A:GLU725 3.1 14.4 1.0 CD A:GLU733 3.4 6.6 1.0 C A:ASP748 3.4 5.6 1.0 CG A:ASN727 3.4 7.6 1.0 CG A:ASP748 3.5 7.5 1.0 CG A:ASN747 3.5 10.2 0.6 N A:ASP748 3.7 6.2 1.0 OE2 A:GLU733 3.8 11.1 1.0 ND2 A:ASN747 3.9 11.1 0.6 CA A:ASP748 4.0 6.1 1.0 ND2 A:ASN727 4.1 9.8 1.0 N A:ASN727 4.1 5.8 1.0 CB A:ASP748 4.3 6.1 1.0 OD2 A:ASP748 4.3 7.9 1.0 O A:HOH988 4.3 18.7 1.0 N A:ILE749 4.5 5.7 1.0 CB A:ASN727 4.5 6.0 1.0 CG A:GLU725 4.6 7.3 1.0 C A:ASN747 4.6 5.7 0.6 N A:ASN728 4.6 5.4 1.0 CG A:GLU733 4.6 6.0 1.0 CA A:ASN727 4.7 7.4 1.0 CB A:GLU733 4.7 5.2 1.0 N A:TYR729 4.7 5.5 1.0 CB A:ASN747 4.7 7.1 0.4 CB A:ASN747 4.7 7.1 0.6 C A:ASN747 4.7 5.6 0.4 CB A:TYR729 4.8 8.4 1.0 C A:ASN727 4.9 6.6 1.0 CA A:ILE749 4.9 6.5 1.0 CA A:ASN747 5.0 6.1 0.6 CA A:ASN747 5.0 6.1 0.4

Calcium binding site 2 out of 2 in the C-Type Carbohydrate-Recognition Domain 4 of the Mannose Receptor


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 2 of C-Type Carbohydrate-Recognition Domain 4 of the Mannose Receptor within 5.0Å range: probe atom residue distance (Å) B Occ B:Ca800 b:6.3 occ:1.00 OD1 B:ASN727 2.3 8.4 1.0 OD1 B:ASP748 2.3 5.8 1.0 O B:ASP748 2.4 5.5 1.0 OE1 B:GLU725 2.4 14.2 1.0 OE1 B:GLU733 2.4 6.7 1.0 OD1 B:ASN747 2.4 10.1 1.0 O B:HOH912 2.5 15.6 1.0 O B:HOH901 2.5 23.7 1.0 OE2 B:GLU725 3.1 17.5 1.0 CD B:GLU725 3.1 11.2 1.0 CD B:GLU733 3.3 8.1 1.0 C B:ASP748 3.4 5.7 1.0 CG B:ASP748 3.4 5.8 1.0 CG B:ASN727 3.5 9.2 1.0 CG B:ASN747 3.5 9.7 1.0 OE2 B:GLU733 3.6 9.2 1.0 N B:ASP748 3.7 5.2 1.0 CA B:ASP748 3.9 5.4 1.0 ND2 B:ASN747 4.0 13.3 1.0 N B:ASN727 4.1 7.6 1.0 ND2 B:ASN727 4.2 11.8 1.0 CB B:ASP748 4.3 4.2 1.0 OD2 B:ASP748 4.3 5.7 1.0 C B:ASN747 4.5 5.1 1.0 N B:ASN728 4.5 6.2 1.0 CG B:GLU725 4.5 8.2 1.0 CB B:ASN727 4.5 8.8 1.0 O B:HOH1002 4.5 27.3 1.0 N B:ILE749 4.6 5.2 1.0 CB B:TYR729 4.6 11.8 1.0 N B:TYR729 4.6 6.8 1.0 CG B:GLU733 4.7 6.7 1.0 O B:HOH1003 4.7 22.2 1.0 CA B:ASN727 4.7 7.2 1.0 CB B:ASN747 4.7 8.0 1.0 CA B:ASN747 4.8 4.7 1.0 CB B:GLU733 4.9 6.0 1.0 C B:ASN727 4.9 8.3 1.0 CA B:ILE749 5.0 6.3 1.0

H.Feinberg, S.A.F.Jegouzo, Y.Lasanajak, D.F.Smith, K.Drickamer, M.E.Taylor, W.I.Weis. Structural Analysis of Carbohydrate Binding By the Macrophage Mannose Receptor CD206 J.Biol.Chem. 2021.
ISSN: ESSN 1083-351X