Calcium in PDB 7m3g: Asymmetric Activation of the Calcium Sensing Receptor Homodimer
Calcium Binding Sites:
The binding sites of Calcium atom in the Asymmetric Activation of the Calcium Sensing Receptor Homodimer
(pdb code 7m3g). This binding sites where shown within
5.0 Angstroms radius around Calcium atom.
In total 4 binding sites of Calcium where determined in the
Asymmetric Activation of the Calcium Sensing Receptor Homodimer, PDB code: 7m3g:
Jump to Calcium binding site number:
1;
2;
3;
4;
Calcium binding site 1 out
of 4 in 7m3g
Go back to
Calcium Binding Sites List in 7m3g
Calcium binding site 1 out
of 4 in the Asymmetric Activation of the Calcium Sensing Receptor Homodimer
 Mono view
 Stereo pair view
|
A full contact list of Calcium with other atoms in the Ca binding
site number 1 of Asymmetric Activation of the Calcium Sensing Receptor Homodimer within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
A:Ca906
b:43.1
occ:1.00
|
O
|
A:SER84
|
2.6
|
34.5
|
1.0
|
O
|
A:ILE81
|
2.8
|
30.0
|
1.0
|
O
|
A:LEU87
|
2.9
|
34.0
|
1.0
|
O
|
A:LEU88
|
3.2
|
34.6
|
1.0
|
O
|
A:ASN82
|
3.5
|
30.9
|
1.0
|
C
|
A:ASN82
|
3.7
|
30.9
|
1.0
|
CA
|
A:ASN82
|
3.7
|
30.9
|
1.0
|
C
|
A:SER84
|
3.8
|
34.5
|
1.0
|
C
|
A:ILE81
|
3.9
|
30.0
|
1.0
|
C
|
A:LEU88
|
4.0
|
34.6
|
1.0
|
C
|
A:LEU87
|
4.1
|
34.0
|
1.0
|
N
|
A:SER84
|
4.1
|
34.5
|
1.0
|
N
|
A:ASN82
|
4.3
|
30.9
|
1.0
|
CA
|
A:SER84
|
4.4
|
34.5
|
1.0
|
N
|
A:SER83
|
4.5
|
32.5
|
1.0
|
O
|
A:LEU91
|
4.6
|
38.0
|
1.0
|
N
|
A:PRO89
|
4.6
|
37.4
|
1.0
|
CA
|
A:PRO89
|
4.6
|
37.4
|
1.0
|
CA
|
A:LEU88
|
4.7
|
34.6
|
1.0
|
C
|
A:SER83
|
4.7
|
32.5
|
1.0
|
CB
|
A:LEU88
|
4.7
|
34.6
|
1.0
|
OD1
|
A:ASN82
|
4.8
|
30.9
|
1.0
|
N
|
A:PRO85
|
4.8
|
36.1
|
1.0
|
CB
|
A:SER84
|
4.8
|
34.5
|
1.0
|
N
|
A:LEU88
|
4.8
|
34.6
|
1.0
|
CA
|
A:PRO85
|
4.9
|
36.1
|
1.0
|
CB
|
A:ASN82
|
5.0
|
30.9
|
1.0
|
CG2
|
A:ILE81
|
5.0
|
30.0
|
1.0
|
|
Calcium binding site 2 out
of 4 in 7m3g
Go back to
Calcium Binding Sites List in 7m3g
Calcium binding site 2 out
of 4 in the Asymmetric Activation of the Calcium Sensing Receptor Homodimer
 Mono view
 Stereo pair view
|
A full contact list of Calcium with other atoms in the Ca binding
site number 2 of Asymmetric Activation of the Calcium Sensing Receptor Homodimer within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
A:Ca907
b:66.5
occ:1.00
|
OD1
|
B:ASP234
|
2.6
|
46.8
|
1.0
|
O
|
A:GLY557
|
2.6
|
55.6
|
1.0
|
C
|
A:GLY557
|
3.5
|
55.6
|
1.0
|
CG
|
B:ASP234
|
3.6
|
46.8
|
1.0
|
OD2
|
B:ASP234
|
3.8
|
46.8
|
1.0
|
CA
|
A:GLY557
|
3.8
|
55.6
|
1.0
|
O
|
B:GLU231
|
4.7
|
46.3
|
1.0
|
N
|
A:GLU558
|
4.7
|
54.8
|
1.0
|
O
|
B:GLU232
|
4.7
|
46.9
|
1.0
|
CB
|
B:ASP234
|
5.0
|
46.8
|
1.0
|
|
Calcium binding site 3 out
of 4 in 7m3g
Go back to
Calcium Binding Sites List in 7m3g
Calcium binding site 3 out
of 4 in the Asymmetric Activation of the Calcium Sensing Receptor Homodimer
 Mono view
 Stereo pair view
|
A full contact list of Calcium with other atoms in the Ca binding
site number 3 of Asymmetric Activation of the Calcium Sensing Receptor Homodimer within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
A:Ca909
b:67.3
occ:1.00
|
O
|
B:GLY557
|
2.8
|
56.3
|
1.0
|
OD1
|
A:ASP234
|
3.5
|
47.2
|
1.0
|
C
|
B:GLY557
|
3.9
|
56.3
|
1.0
|
O
|
A:GLU231
|
4.2
|
48.9
|
1.0
|
CG
|
A:ASP234
|
4.5
|
47.2
|
1.0
|
CA
|
B:GLY557
|
4.6
|
56.3
|
1.0
|
N
|
B:GLU558
|
4.8
|
55.4
|
1.0
|
OD2
|
A:ASP234
|
4.9
|
47.2
|
1.0
|
CA
|
B:GLU558
|
4.9
|
55.4
|
1.0
|
|
Calcium binding site 4 out
of 4 in 7m3g
Go back to
Calcium Binding Sites List in 7m3g
Calcium binding site 4 out
of 4 in the Asymmetric Activation of the Calcium Sensing Receptor Homodimer
 Mono view
 Stereo pair view
|
A full contact list of Calcium with other atoms in the Ca binding
site number 4 of Asymmetric Activation of the Calcium Sensing Receptor Homodimer within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
B:Ca905
b:40.9
occ:1.00
|
O
|
B:SER84
|
2.5
|
34.1
|
1.0
|
O
|
B:LEU87
|
2.6
|
33.0
|
1.0
|
O
|
B:ILE81
|
2.8
|
29.3
|
1.0
|
O
|
B:LEU88
|
3.1
|
33.6
|
1.0
|
C
|
B:SER84
|
3.6
|
34.1
|
1.0
|
O
|
B:ASN82
|
3.7
|
30.2
|
1.0
|
C
|
B:LEU87
|
3.8
|
33.0
|
1.0
|
C
|
B:LEU88
|
3.8
|
33.6
|
1.0
|
C
|
B:ILE81
|
3.9
|
29.3
|
1.0
|
C
|
B:ASN82
|
3.9
|
30.2
|
1.0
|
N
|
B:SER84
|
4.0
|
34.1
|
1.0
|
CA
|
B:ASN82
|
4.0
|
30.2
|
1.0
|
OG
|
B:SER84
|
4.2
|
34.1
|
1.0
|
CA
|
B:SER84
|
4.3
|
34.1
|
1.0
|
N
|
B:ASN82
|
4.4
|
30.2
|
1.0
|
N
|
B:PRO89
|
4.5
|
35.7
|
1.0
|
CA
|
B:LEU88
|
4.5
|
33.6
|
1.0
|
N
|
B:LEU88
|
4.5
|
33.6
|
1.0
|
CB
|
B:LEU88
|
4.6
|
33.6
|
1.0
|
CA
|
B:PRO89
|
4.6
|
35.7
|
1.0
|
N
|
B:PRO85
|
4.6
|
34.8
|
1.0
|
O
|
B:LEU91
|
4.7
|
36.5
|
1.0
|
N
|
B:SER83
|
4.7
|
32.4
|
1.0
|
CA
|
B:PRO85
|
4.7
|
34.8
|
1.0
|
N
|
B:LEU87
|
4.8
|
33.0
|
1.0
|
CA
|
B:LEU87
|
4.8
|
33.0
|
1.0
|
CB
|
B:SER84
|
4.8
|
34.1
|
1.0
|
C
|
B:SER83
|
4.9
|
32.4
|
1.0
|
|
Reference:
Y.Gao,
M.J.Robertson,
S.N.Rahman,
A.B.Seven,
C.Zhang,
J.G.Meyerowitz,
O.Panova,
F.M.Hannan,
R.V.Thakker,
H.Brauner-Osborne,
J.M.Mathiesen,
G.Skiniotis.
Asymmetric Activation of the Calcium-Sensing Receptor Homodimer Nature 2021.
ISSN: ESSN 1476-4687
DOI: 10.1038/S41586-021-03691-0
Page generated: Wed Jul 9 23:23:33 2025
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