Calcium in PDB 7mxw: Crystal Structure of Human Exonuclease 1 EXO1 (Wt) in Complex with 5' Flap Dna (UF1)

The structure of Crystal Structure of Human Exonuclease 1 EXO1 (Wt) in Complex with 5' Flap Dna (UF1), PDB code: 7mxw was solved by Y.Shi, L.S.Beese, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	30.30 / 2.84
Space group	P 43 21 2
Cell size a, b, c (Å), α, β, γ (°)	71.955, 71.955, 179.874, 90, 90, 90
R / Rfree (%)	21.9 / 26.5

The structure of Crystal Structure of Human Exonuclease 1 EXO1 (Wt) in Complex with 5' Flap Dna (UF1) also contains other interesting chemical elements:

Magnesium

(Mg)

3 atoms

The binding sites of Calcium atom in the Crystal Structure of Human Exonuclease 1 EXO1 (Wt) in Complex with 5' Flap Dna (UF1) (pdb code 7mxw). This binding sites where shown within 5.0 Angstroms radius around Calcium atom.
In total 2 binding sites of Calcium where determined in the Crystal Structure of Human Exonuclease 1 EXO1 (Wt) in Complex with 5' Flap Dna (UF1), PDB code: 7mxw:
Jump to Calcium binding site number: 1; 2;

Calcium binding site 1 out of 2 in the Crystal Structure of Human Exonuclease 1 EXO1 (Wt) in Complex with 5' Flap Dna (UF1)


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 1 of Crystal Structure of Human Exonuclease 1 EXO1 (Wt) in Complex with 5' Flap Dna (UF1) within 5.0Å range: probe atom residue distance (Å) B Occ Z:Ca404 b:72.5 occ:1.00 SG Z:CYS80 2.7 75.1 1.0 CB Z:CYS80 3.7 74.8 1.0 CD1 Z:ILE325 3.8 79.4 1.0 CG1 Z:VAL317 4.2 82.3 1.0 CZ Z:PHE335 4.3 85.2 1.0 CE1 Z:PHE335 4.4 84.8 1.0 O Z:PRO148 4.4 65.6 1.0 OH Z:TYR149 4.4 75.6 1.0 CZ Z:TYR149 4.6 74.4 1.0 CE1 Z:TYR149 4.8 72.0 1.0 CG2 Z:VAL317 4.9 78.8 1.0

Calcium binding site 2 out of 2 in the Crystal Structure of Human Exonuclease 1 EXO1 (Wt) in Complex with 5' Flap Dna (UF1)


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 2 of Crystal Structure of Human Exonuclease 1 EXO1 (Wt) in Complex with 5' Flap Dna (UF1) within 5.0Å range: probe atom residue distance (Å) B Occ Z:Ca405 b:93.0 occ:1.00 N Z:HIS18 4.1 86.2 1.0 CB Z:LYS21 4.2 80.1 1.0 NH1 Z:ARG20 4.5 92.8 1.0 O Z:HIS18 4.5 87.2 1.0 CA Z:ILE17 4.6 78.2 1.0 CB Z:ILE17 4.7 78.1 1.0 C Z:ILE17 4.8 77.5 1.0 CB Z:HIS18 4.8 87.7 1.0 CG Z:LYS21 4.9 80.9 1.0 CA Z:LYS21 4.9 81.8 1.0 CD Z:LYS21 4.9 79.2 1.0 CA Z:HIS18 4.9 85.7 1.0

Y.Shi, H.W.Hellinga, L.S.Beese. Structures of Reaction Intermediates Reveal Transient MG2+-Binding Events That Dynamically Coordinate Human Exonuclease I Activities To Be Published.