Calcium in PDB 7nqc: Calmodulin Extracts the Ras Family Protein Rala From Lipid Bilayers By Engagement with Two Membrane Targeting Motifs

All present enzymatic activity of Calmodulin Extracts the Ras Family Protein Rala From Lipid Bilayers By Engagement with Two Membrane Targeting Motifs:
3.6.5.2;

The binding sites of Calcium atom in the Calmodulin Extracts the Ras Family Protein Rala From Lipid Bilayers By Engagement with Two Membrane Targeting Motifs (pdb code 7nqc). This binding sites where shown within 5.0 Angstroms radius around Calcium atom.
In total 4 binding sites of Calcium where determined in the Calmodulin Extracts the Ras Family Protein Rala From Lipid Bilayers By Engagement with Two Membrane Targeting Motifs, PDB code: 7nqc:
Jump to Calcium binding site number: 1; 2; 3; 4;

Calcium binding site 1 out of 4 in the Calmodulin Extracts the Ras Family Protein Rala From Lipid Bilayers By Engagement with Two Membrane Targeting Motifs


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 1 of Calmodulin Extracts the Ras Family Protein Rala From Lipid Bilayers By Engagement with Two Membrane Targeting Motifs within 5.0Å range: probe atom residue distance (Å) B Occ A:Ca1001 b:10.0 occ:1.00 OD2 A:ASP22 2.3 10.0 1.0 O A:THR26 2.3 10.0 1.0 OE1 A:GLU31 2.3 10.0 1.0 OE2 A:GLU31 2.4 10.0 1.0 OD2 A:ASP24 2.4 10.0 1.0 OD1 A:ASP20 2.4 10.0 1.0 OD1 A:ASP22 2.6 10.0 1.0 OD1 A:ASP24 2.6 10.0 1.0 CD A:GLU31 2.7 10.0 1.0 CG A:ASP24 2.7 10.0 1.0 CG A:ASP22 2.8 10.0 1.0 H A:ASP24 3.1 10.0 1.0 HA A:ASP20 3.2 10.0 1.0 H A:THR26 3.3 10.0 1.0 C A:THR26 3.5 10.0 1.0 HG1 A:THR26 3.6 10.0 1.0 CG A:ASP20 3.6 10.0 1.0 HA A:ILE27 3.7 10.0 1.0 H A:ASP22 3.8 10.0 1.0 H A:GLY23 4.0 10.0 1.0 H A:GLY25 4.0 10.0 1.0 CB A:ASP24 4.0 10.0 1.0 N A:ASP24 4.0 10.0 1.0 N A:THR26 4.1 10.0 1.0 CA A:ASP20 4.1 10.0 1.0 CG A:GLU31 4.1 10.0 1.0 CB A:ASP22 4.2 10.0 1.0 CB A:ASP20 4.2 10.0 1.0 HB2 A:ASP20 4.3 10.0 1.0 H A:THR28 4.3 10.0 1.0 CA A:THR26 4.3 10.0 1.0 OG1 A:THR26 4.4 10.0 1.0 HB3 A:ASP24 4.4 10.0 1.0 H A:LYS21 4.4 10.0 1.0 N A:ILE27 4.4 10.0 1.0 HG21 A:THR28 4.5 10.0 1.0 CA A:ASP24 4.5 10.0 1.0 HG3 A:GLU31 4.5 10.0 1.0 CA A:ILE27 4.5 10.0 1.0 HG2 A:GLU31 4.5 10.0 1.0 N A:GLY23 4.5 10.0 1.0 N A:ASP22 4.5 10.0 1.0 N A:GLY25 4.5 10.0 1.0 OD2 A:ASP20 4.6 10.0 1.0 C A:ASP20 4.6 10.0 1.0 HG1 A:THR28 4.7 10.0 1.0 O A:PHE19 4.7 10.0 1.0 HB3 A:ASP22 4.7 10.0 1.0 N A:LYS21 4.7 10.0 1.0 HB2 A:ASP22 4.8 10.0 1.0 HB2 A:ASP24 4.8 10.0 1.0 CA A:ASP22 4.8 10.0 1.0 C A:ASP24 4.9 10.0 1.0 CB A:THR26 5.0 10.0 1.0 N A:THR28 5.0 10.0 1.0 C A:ASP22 5.0 10.0 1.0

Calcium binding site 2 out of 4 in the Calmodulin Extracts the Ras Family Protein Rala From Lipid Bilayers By Engagement with Two Membrane Targeting Motifs


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 2 of Calmodulin Extracts the Ras Family Protein Rala From Lipid Bilayers By Engagement with Two Membrane Targeting Motifs within 5.0Å range: probe atom residue distance (Å) B Occ A:Ca1002 b:10.0 occ:1.00 OD1 A:ASP64 2.3 10.0 1.0 OD1 A:ASP56 2.3 10.0 1.0 OD1 A:ASP58 2.3 10.0 1.0 OE2 A:GLU67 2.4 10.0 1.0 OE1 A:GLU67 2.4 10.0 1.0 O A:THR62 2.4 10.0 1.0 OD1 A:ASN60 2.5 10.0 1.0 CD A:GLU67 2.7 10.0 1.0 HB2 A:ASP58 3.0 10.0 1.0 H A:ASP58 3.3 10.0 1.0 CG A:ASP58 3.3 10.0 1.0 H A:ASP64 3.4 10.0 1.0 CG A:ASP56 3.4 10.0 1.0 CG A:ASN60 3.5 10.0 1.0 CG A:ASP64 3.5 10.0 1.0 HA A:ASP56 3.5 10.0 1.0 HA A:ILE63 3.6 10.0 1.0 HD22 A:ASN60 3.6 10.0 1.0 CB A:ASP58 3.6 10.0 1.0 C A:THR62 3.7 10.0 1.0 H A:ASN60 3.9 10.0 1.0 H A:THR62 3.9 10.0 1.0 ND2 A:ASN60 4.0 10.0 1.0 H A:ALA57 4.0 10.0 1.0 N A:ASP64 4.1 10.0 1.0 N A:ASP58 4.1 10.0 1.0 HB2 A:ASP64 4.2 10.0 1.0 OD2 A:ASP56 4.2 10.0 1.0 CG A:GLU67 4.2 10.0 1.0 CB A:ASP56 4.3 10.0 1.0 CA A:ASP56 4.3 10.0 1.0 CA A:ILE63 4.4 10.0 1.0 CB A:ASP64 4.4 10.0 1.0 OD2 A:ASP64 4.4 10.0 1.0 HB2 A:ASP56 4.4 10.0 1.0 OG1 A:THR62 4.4 10.0 1.0 CA A:ASP58 4.5 10.0 1.0 HG3 A:GLU67 4.5 10.0 1.0 N A:ILE63 4.5 10.0 1.0 OD2 A:ASP58 4.5 10.0 1.0 HB3 A:ASP58 4.5 10.0 1.0 N A:ALA57 4.5 10.0 1.0 H A:GLY59 4.5 10.0 1.0 C A:ILE63 4.6 10.0 1.0 N A:THR62 4.6 10.0 1.0 CA A:THR62 4.7 10.0 1.0 C A:ASP56 4.7 10.0 1.0 CB A:ASN60 4.7 10.0 1.0 H A:GLY61 4.7 10.0 1.0 HG2 A:GLU67 4.7 10.0 1.0 N A:ASN60 4.8 10.0 1.0 HB3 A:ASN60 4.8 10.0 1.0 CA A:ASP64 4.9 10.0 1.0 HD21 A:ASN60 4.9 10.0 1.0 HB2 A:GLU67 4.9 10.0 1.0 N A:GLY59 4.9 10.0 1.0 HD11 A:ILE63 5.0 10.0 1.0

Calcium binding site 3 out of 4 in the Calmodulin Extracts the Ras Family Protein Rala From Lipid Bilayers By Engagement with Two Membrane Targeting Motifs


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 3 of Calmodulin Extracts the Ras Family Protein Rala From Lipid Bilayers By Engagement with Two Membrane Targeting Motifs within 5.0Å range: probe atom residue distance (Å) B Occ A:Ca1003 b:10.0 occ:1.00 OD2 A:ASP95 2.2 10.0 1.0 OD1 A:ASP93 2.2 10.0 1.0 O A:TYR99 2.3 10.0 1.0 OE1 A:GLU104 2.3 10.0 1.0 OE2 A:GLU104 2.3 10.0 1.0 OD1 A:ASN97 2.4 10.0 1.0 CG A:ASP95 2.4 10.0 1.0 OD1 A:ASP95 2.4 10.0 1.0 CD A:GLU104 2.6 10.0 1.0 H A:ASN97 3.0 10.0 1.0 H A:GLY96 3.3 10.0 1.0 CG A:ASP93 3.4 10.0 1.0 CG A:ASN97 3.4 10.0 1.0 H A:ASP95 3.4 10.0 1.0 H A:TYR99 3.5 10.0 1.0 HA A:ASP93 3.5 10.0 1.0 C A:TYR99 3.5 10.0 1.0 HA A:ILE100 3.5 10.0 1.0 CB A:ASP95 3.7 10.0 1.0 N A:GLY96 3.9 10.0 1.0 HB3 A:ASP95 3.9 10.0 1.0 N A:ASN97 3.9 10.0 1.0 H A:SER101 3.9 10.0 1.0 CG A:GLU104 4.1 10.0 1.0 HD22 A:ASN97 4.1 10.0 1.0 N A:ASP95 4.1 10.0 1.0 OD2 A:ASP93 4.2 10.0 1.0 HB2 A:TYR99 4.2 10.0 1.0 ND2 A:ASN97 4.2 10.0 1.0 CA A:ASP95 4.2 10.0 1.0 CA A:ASP93 4.2 10.0 1.0 N A:TYR99 4.3 10.0 1.0 HB3 A:ASN97 4.3 10.0 1.0 CB A:ASP93 4.3 10.0 1.0 H A:GLY98 4.3 10.0 1.0 CB A:ASN97 4.3 10.0 1.0 C A:ASP95 4.3 10.0 1.0 N A:ILE100 4.4 10.0 1.0 CA A:ILE100 4.4 10.0 1.0 CA A:TYR99 4.4 10.0 1.0 HG3 A:GLU104 4.4 10.0 1.0 HG2 A:GLU104 4.4 10.0 1.0 HB2 A:ASP95 4.5 10.0 1.0 HB2 A:ASP93 4.5 10.0 1.0 C A:ASP93 4.6 10.0 1.0 CA A:ASN97 4.6 10.0 1.0 OE1 A:GLN135 4.7 10.0 1.0 N A:SER101 4.7 10.0 1.0 CA A:GLY96 4.7 10.0 1.0 H A:LYS94 4.7 10.0 1.0 C A:GLY96 4.8 10.0 1.0 N A:GLY98 4.8 10.0 1.0 HA2 A:GLY96 4.8 10.0 1.0 CB A:TYR99 4.8 10.0 1.0 N A:LYS94 4.8 10.0 1.0

Calcium binding site 4 out of 4 in the Calmodulin Extracts the Ras Family Protein Rala From Lipid Bilayers By Engagement with Two Membrane Targeting Motifs


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 4 of Calmodulin Extracts the Ras Family Protein Rala From Lipid Bilayers By Engagement with Two Membrane Targeting Motifs within 5.0Å range: probe atom residue distance (Å) B Occ A:Ca1004 b:10.0 occ:1.00 OD1 A:ASP129 2.2 10.0 1.0 OD1 A:ASP131 2.3 10.0 1.0 O A:GLN135 2.3 10.0 1.0 OE2 A:GLU140 2.4 10.0 1.0 OE1 A:GLU140 2.4 10.0 1.0 OD1 A:ASP133 2.4 10.0 1.0 OD2 A:ASP131 2.5 10.0 1.0 CG A:ASP131 2.6 10.0 1.0 CD A:GLU140 2.7 10.0 1.0 H A:ASP133 3.1 10.0 1.0 HA A:VAL136 3.2 10.0 1.0 H A:ASP131 3.3 10.0 1.0 H A:GLN135 3.5 10.0 1.0 CG A:ASP129 3.5 10.0 1.0 C A:GLN135 3.5 10.0 1.0 CG A:ASP133 3.6 10.0 1.0 HB3 A:ASP133 3.6 10.0 1.0 HA A:ASP129 3.6 10.0 1.0 HD21 A:ASN137 3.8 10.0 1.0 H A:GLY132 3.9 10.0 1.0 H A:ASN137 3.9 10.0 1.0 N A:ASP133 3.9 10.0 1.0 CB A:ASP131 4.0 10.0 1.0 CB A:ASP133 4.1 10.0 1.0 N A:ASP131 4.1 10.0 1.0 H A:ILE130 4.1 10.0 1.0 CA A:VAL136 4.1 10.0 1.0 OD2 A:ASP129 4.2 10.0 1.0 N A:GLY132 4.2 10.0 1.0 CG A:GLU140 4.2 10.0 1.0 N A:VAL136 4.3 10.0 1.0 N A:GLN135 4.3 10.0 1.0 H A:GLY134 4.3 10.0 1.0 HB2 A:GLN135 4.3 10.0 1.0 HG13 A:VAL136 4.4 10.0 1.0 CA A:ASP129 4.4 10.0 1.0 CA A:ASP131 4.4 10.0 1.0 CB A:ASP129 4.4 10.0 1.0 CA A:GLN135 4.5 10.0 1.0 C A:ASP131 4.5 10.0 1.0 N A:ILE130 4.5 10.0 1.0 CA A:ASP133 4.5 10.0 1.0 HB3 A:ASP131 4.5 10.0 1.0 OD2 A:ASP133 4.6 10.0 1.0 N A:ASN137 4.6 10.0 1.0 ND2 A:ASN137 4.6 10.0 1.0 C A:ASP129 4.6 10.0 1.0 HG2 A:GLU140 4.7 10.0 1.0 HB2 A:ASP131 4.7 10.0 1.0 HG3 A:GLU140 4.7 10.0 1.0 N A:GLY134 4.8 10.0 1.0 HB2 A:ASP129 4.8 10.0 1.0 C A:VAL136 4.9 10.0 1.0 HB2 A:GLU140 4.9 10.0 1.0 C A:GLY132 4.9 10.0 1.0 HB3 A:GLU140 4.9 10.0 1.0 CB A:GLN135 4.9 10.0 1.0 HD2 A:TYR99 5.0 10.0 1.0 HD22 A:ASN137 5.0 10.0 1.0 CA A:GLY132 5.0 10.0 1.0 HA2 A:GLY132 5.0 10.0 1.0 CB A:GLU140 5.0 10.0 1.0

S.G.Chamberlain, A.Gohlke, A.Shafiq, I.J.Squires, D.Owen, H.R.Mott. Calmodulin Extracts the Ras Family Protein Rala From Lipid Bilayers By Engagement with Two Membrane-Targeting Motifs. Proc.Natl.Acad.Sci.Usa V. 118 2021.
ISSN: ESSN 1091-6490
PubMed: 34480001
DOI: 10.1073/PNAS.2104219118