Calcium in PDB 7or1: Cryo-Em Structure of the Human TRPA1 Ion Channel in Complex with the Antagonist 3-60, Conformation 1
Calcium Binding Sites:
The binding sites of Calcium atom in the Cryo-Em Structure of the Human TRPA1 Ion Channel in Complex with the Antagonist 3-60, Conformation 1
(pdb code 7or1). This binding sites where shown within
5.0 Angstroms radius around Calcium atom.
In total 5 binding sites of Calcium where determined in the
Cryo-Em Structure of the Human TRPA1 Ion Channel in Complex with the Antagonist 3-60, Conformation 1, PDB code: 7or1:
Jump to Calcium binding site number:
1;
2;
3;
4;
5;
Calcium binding site 1 out
of 5 in 7or1
Go back to
Calcium Binding Sites List in 7or1
Calcium binding site 1 out
of 5 in the Cryo-Em Structure of the Human TRPA1 Ion Channel in Complex with the Antagonist 3-60, Conformation 1
 Mono view
 Stereo pair view
|
A full contact list of Calcium with other atoms in the Ca binding
site number 1 of Cryo-Em Structure of the Human TRPA1 Ion Channel in Complex with the Antagonist 3-60, Conformation 1 within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
A:Ca1204
b:114.0
occ:1.00
|
OD1
|
A:ASN805
|
2.5
|
103.2
|
1.0
|
OE2
|
A:GLU788
|
2.5
|
115.4
|
1.0
|
OE1
|
A:GLN791
|
3.1
|
122.9
|
1.0
|
CD
|
A:GLU788
|
3.3
|
115.4
|
1.0
|
OE1
|
A:GLU788
|
3.3
|
115.4
|
1.0
|
OE1
|
A:GLU808
|
3.3
|
89.3
|
1.0
|
CG
|
A:ASN805
|
3.7
|
103.2
|
1.0
|
CD
|
A:GLN791
|
4.0
|
122.9
|
1.0
|
CA
|
A:ASN805
|
4.2
|
103.2
|
1.0
|
NE2
|
A:GLN791
|
4.3
|
122.9
|
1.0
|
CD
|
A:GLU808
|
4.3
|
89.3
|
1.0
|
N
|
A:ASN805
|
4.4
|
103.2
|
1.0
|
CB
|
A:ASN805
|
4.5
|
103.2
|
1.0
|
OG
|
A:SER804
|
4.6
|
98.0
|
1.0
|
ND2
|
A:ASN805
|
4.7
|
103.2
|
1.0
|
C
|
A:SER804
|
4.7
|
98.0
|
1.0
|
CG
|
A:GLU788
|
4.7
|
115.4
|
1.0
|
O
|
A:SER804
|
4.8
|
98.0
|
1.0
|
CE1
|
A:TYR799
|
5.0
|
118.6
|
1.0
|
|
Calcium binding site 2 out
of 5 in 7or1
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Calcium Binding Sites List in 7or1
Calcium binding site 2 out
of 5 in the Cryo-Em Structure of the Human TRPA1 Ion Channel in Complex with the Antagonist 3-60, Conformation 1
 Mono view
 Stereo pair view
|
A full contact list of Calcium with other atoms in the Ca binding
site number 2 of Cryo-Em Structure of the Human TRPA1 Ion Channel in Complex with the Antagonist 3-60, Conformation 1 within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
B:Ca1204
b:117.0
occ:1.00
|
OD1
|
B:ASN805
|
2.5
|
104.1
|
1.0
|
OE2
|
B:GLU788
|
2.5
|
117.0
|
1.0
|
OE1
|
B:GLN791
|
3.1
|
124.1
|
1.0
|
CD
|
B:GLU788
|
3.3
|
117.0
|
1.0
|
OE1
|
B:GLU788
|
3.3
|
117.0
|
1.0
|
OE1
|
B:GLU808
|
3.3
|
91.0
|
1.0
|
CG
|
B:ASN805
|
3.7
|
104.1
|
1.0
|
CD
|
B:GLN791
|
4.0
|
124.1
|
1.0
|
CA
|
B:ASN805
|
4.2
|
104.1
|
1.0
|
NE2
|
B:GLN791
|
4.3
|
124.1
|
1.0
|
CD
|
B:GLU808
|
4.3
|
91.0
|
1.0
|
N
|
B:ASN805
|
4.4
|
104.1
|
1.0
|
CB
|
B:ASN805
|
4.5
|
104.1
|
1.0
|
OG
|
B:SER804
|
4.6
|
99.6
|
1.0
|
ND2
|
B:ASN805
|
4.7
|
104.1
|
1.0
|
C
|
B:SER804
|
4.7
|
99.6
|
1.0
|
CG
|
B:GLU788
|
4.7
|
117.0
|
1.0
|
O
|
B:SER804
|
4.8
|
99.6
|
1.0
|
CE1
|
B:TYR799
|
5.0
|
119.3
|
1.0
|
|
Calcium binding site 3 out
of 5 in 7or1
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Calcium Binding Sites List in 7or1
Calcium binding site 3 out
of 5 in the Cryo-Em Structure of the Human TRPA1 Ion Channel in Complex with the Antagonist 3-60, Conformation 1
 Mono view
 Stereo pair view
|
A full contact list of Calcium with other atoms in the Ca binding
site number 3 of Cryo-Em Structure of the Human TRPA1 Ion Channel in Complex with the Antagonist 3-60, Conformation 1 within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
B:Ca1207
b:128.2
occ:1.00
|
O
|
B:HOH1313
|
4.6
|
64.7
|
1.0
|
O
|
A:HOH1312
|
4.7
|
63.7
|
1.0
|
O
|
D:HOH1311
|
4.7
|
64.2
|
1.0
|
O
|
C:HOH1312
|
4.7
|
64.0
|
1.0
|
|
Calcium binding site 4 out
of 5 in 7or1
Go back to
Calcium Binding Sites List in 7or1
Calcium binding site 4 out
of 5 in the Cryo-Em Structure of the Human TRPA1 Ion Channel in Complex with the Antagonist 3-60, Conformation 1
 Mono view
 Stereo pair view
|
A full contact list of Calcium with other atoms in the Ca binding
site number 4 of Cryo-Em Structure of the Human TRPA1 Ion Channel in Complex with the Antagonist 3-60, Conformation 1 within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
C:Ca1204
b:113.6
occ:1.00
|
OD1
|
C:ASN805
|
2.5
|
102.2
|
1.0
|
OE2
|
C:GLU788
|
2.5
|
114.7
|
1.0
|
OE1
|
C:GLN791
|
3.1
|
121.7
|
1.0
|
CD
|
C:GLU788
|
3.3
|
114.7
|
1.0
|
OE1
|
C:GLU788
|
3.3
|
114.7
|
1.0
|
OE1
|
C:GLU808
|
3.3
|
88.7
|
1.0
|
CG
|
C:ASN805
|
3.7
|
102.2
|
1.0
|
CD
|
C:GLN791
|
4.0
|
121.7
|
1.0
|
CA
|
C:ASN805
|
4.2
|
102.2
|
1.0
|
NE2
|
C:GLN791
|
4.3
|
121.7
|
1.0
|
CD
|
C:GLU808
|
4.3
|
88.7
|
1.0
|
N
|
C:ASN805
|
4.4
|
102.2
|
1.0
|
CB
|
C:ASN805
|
4.5
|
102.2
|
1.0
|
OG
|
C:SER804
|
4.6
|
97.6
|
1.0
|
ND2
|
C:ASN805
|
4.7
|
102.2
|
1.0
|
C
|
C:SER804
|
4.7
|
97.6
|
1.0
|
CG
|
C:GLU788
|
4.7
|
114.7
|
1.0
|
O
|
C:SER804
|
4.8
|
97.6
|
1.0
|
CE1
|
C:TYR799
|
5.0
|
117.4
|
1.0
|
|
Calcium binding site 5 out
of 5 in 7or1
Go back to
Calcium Binding Sites List in 7or1
Calcium binding site 5 out
of 5 in the Cryo-Em Structure of the Human TRPA1 Ion Channel in Complex with the Antagonist 3-60, Conformation 1
 Mono view
 Stereo pair view
|
A full contact list of Calcium with other atoms in the Ca binding
site number 5 of Cryo-Em Structure of the Human TRPA1 Ion Channel in Complex with the Antagonist 3-60, Conformation 1 within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
D:Ca1205
b:114.4
occ:1.00
|
OD1
|
D:ASN805
|
2.5
|
103.0
|
1.0
|
OE2
|
D:GLU788
|
2.5
|
115.4
|
1.0
|
OE1
|
D:GLN791
|
3.1
|
122.8
|
1.0
|
CD
|
D:GLU788
|
3.3
|
115.4
|
1.0
|
OE1
|
D:GLU788
|
3.3
|
115.4
|
1.0
|
OE1
|
D:GLU808
|
3.3
|
90.3
|
1.0
|
CG
|
D:ASN805
|
3.7
|
103.0
|
1.0
|
CD
|
D:GLN791
|
4.0
|
122.8
|
1.0
|
CA
|
D:ASN805
|
4.2
|
103.0
|
1.0
|
NE2
|
D:GLN791
|
4.3
|
122.8
|
1.0
|
CD
|
D:GLU808
|
4.3
|
90.3
|
1.0
|
N
|
D:ASN805
|
4.4
|
103.0
|
1.0
|
CB
|
D:ASN805
|
4.5
|
103.0
|
1.0
|
OG
|
D:SER804
|
4.6
|
98.6
|
1.0
|
ND2
|
D:ASN805
|
4.7
|
103.0
|
1.0
|
C
|
D:SER804
|
4.7
|
98.6
|
1.0
|
CG
|
D:GLU788
|
4.7
|
115.4
|
1.0
|
O
|
D:SER804
|
4.8
|
98.6
|
1.0
|
CE1
|
D:TYR799
|
5.0
|
118.4
|
1.0
|
|
Reference:
M.Grieben,
B.G.Saward,
A.C.W.Pike,
C.J.Schofield,
E.P.Carpenter.
Cryo-Em Structure of the Human TRPA1 Ion Channel in Complex with the Antagonist 3-60 To Be Published.
Page generated: Fri Jul 19 02:35:35 2024
|