Calcium in PDB 7or1: Cryo-Em Structure of the Human TRPA1 Ion Channel in Complex with the Antagonist 3-60, Conformation 1

The binding sites of Calcium atom in the Cryo-Em Structure of the Human TRPA1 Ion Channel in Complex with the Antagonist 3-60, Conformation 1 (pdb code 7or1). This binding sites where shown within 5.0 Angstroms radius around Calcium atom.
In total 5 binding sites of Calcium where determined in the Cryo-Em Structure of the Human TRPA1 Ion Channel in Complex with the Antagonist 3-60, Conformation 1, PDB code: 7or1:
Jump to Calcium binding site number: 1; 2; 3; 4; 5;

Calcium binding site 1 out of 5 in the Cryo-Em Structure of the Human TRPA1 Ion Channel in Complex with the Antagonist 3-60, Conformation 1


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 1 of Cryo-Em Structure of the Human TRPA1 Ion Channel in Complex with the Antagonist 3-60, Conformation 1 within 5.0Å range: probe atom residue distance (Å) B Occ A:Ca1204 b:114.0 occ:1.00 OD1 A:ASN805 2.5 103.2 1.0 OE2 A:GLU788 2.5 115.4 1.0 OE1 A:GLN791 3.1 122.9 1.0 CD A:GLU788 3.3 115.4 1.0 OE1 A:GLU788 3.3 115.4 1.0 OE1 A:GLU808 3.3 89.3 1.0 CG A:ASN805 3.7 103.2 1.0 CD A:GLN791 4.0 122.9 1.0 CA A:ASN805 4.2 103.2 1.0 NE2 A:GLN791 4.3 122.9 1.0 CD A:GLU808 4.3 89.3 1.0 N A:ASN805 4.4 103.2 1.0 CB A:ASN805 4.5 103.2 1.0 OG A:SER804 4.6 98.0 1.0 ND2 A:ASN805 4.7 103.2 1.0 C A:SER804 4.7 98.0 1.0 CG A:GLU788 4.7 115.4 1.0 O A:SER804 4.8 98.0 1.0 CE1 A:TYR799 5.0 118.6 1.0

Calcium binding site 2 out of 5 in the Cryo-Em Structure of the Human TRPA1 Ion Channel in Complex with the Antagonist 3-60, Conformation 1


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 2 of Cryo-Em Structure of the Human TRPA1 Ion Channel in Complex with the Antagonist 3-60, Conformation 1 within 5.0Å range: probe atom residue distance (Å) B Occ B:Ca1204 b:117.0 occ:1.00 OD1 B:ASN805 2.5 104.1 1.0 OE2 B:GLU788 2.5 117.0 1.0 OE1 B:GLN791 3.1 124.1 1.0 CD B:GLU788 3.3 117.0 1.0 OE1 B:GLU788 3.3 117.0 1.0 OE1 B:GLU808 3.3 91.0 1.0 CG B:ASN805 3.7 104.1 1.0 CD B:GLN791 4.0 124.1 1.0 CA B:ASN805 4.2 104.1 1.0 NE2 B:GLN791 4.3 124.1 1.0 CD B:GLU808 4.3 91.0 1.0 N B:ASN805 4.4 104.1 1.0 CB B:ASN805 4.5 104.1 1.0 OG B:SER804 4.6 99.6 1.0 ND2 B:ASN805 4.7 104.1 1.0 C B:SER804 4.7 99.6 1.0 CG B:GLU788 4.7 117.0 1.0 O B:SER804 4.8 99.6 1.0 CE1 B:TYR799 5.0 119.3 1.0

Calcium binding site 3 out of 5 in the Cryo-Em Structure of the Human TRPA1 Ion Channel in Complex with the Antagonist 3-60, Conformation 1


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 3 of Cryo-Em Structure of the Human TRPA1 Ion Channel in Complex with the Antagonist 3-60, Conformation 1 within 5.0Å range: probe atom residue distance (Å) B Occ B:Ca1207 b:128.2 occ:1.00 O B:HOH1313 4.6 64.7 1.0 O A:HOH1312 4.7 63.7 1.0 O D:HOH1311 4.7 64.2 1.0 O C:HOH1312 4.7 64.0 1.0

Calcium binding site 4 out of 5 in the Cryo-Em Structure of the Human TRPA1 Ion Channel in Complex with the Antagonist 3-60, Conformation 1


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 4 of Cryo-Em Structure of the Human TRPA1 Ion Channel in Complex with the Antagonist 3-60, Conformation 1 within 5.0Å range: probe atom residue distance (Å) B Occ C:Ca1204 b:113.6 occ:1.00 OD1 C:ASN805 2.5 102.2 1.0 OE2 C:GLU788 2.5 114.7 1.0 OE1 C:GLN791 3.1 121.7 1.0 CD C:GLU788 3.3 114.7 1.0 OE1 C:GLU788 3.3 114.7 1.0 OE1 C:GLU808 3.3 88.7 1.0 CG C:ASN805 3.7 102.2 1.0 CD C:GLN791 4.0 121.7 1.0 CA C:ASN805 4.2 102.2 1.0 NE2 C:GLN791 4.3 121.7 1.0 CD C:GLU808 4.3 88.7 1.0 N C:ASN805 4.4 102.2 1.0 CB C:ASN805 4.5 102.2 1.0 OG C:SER804 4.6 97.6 1.0 ND2 C:ASN805 4.7 102.2 1.0 C C:SER804 4.7 97.6 1.0 CG C:GLU788 4.7 114.7 1.0 O C:SER804 4.8 97.6 1.0 CE1 C:TYR799 5.0 117.4 1.0

Calcium binding site 5 out of 5 in the Cryo-Em Structure of the Human TRPA1 Ion Channel in Complex with the Antagonist 3-60, Conformation 1


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 5 of Cryo-Em Structure of the Human TRPA1 Ion Channel in Complex with the Antagonist 3-60, Conformation 1 within 5.0Å range: probe atom residue distance (Å) B Occ D:Ca1205 b:114.4 occ:1.00 OD1 D:ASN805 2.5 103.0 1.0 OE2 D:GLU788 2.5 115.4 1.0 OE1 D:GLN791 3.1 122.8 1.0 CD D:GLU788 3.3 115.4 1.0 OE1 D:GLU788 3.3 115.4 1.0 OE1 D:GLU808 3.3 90.3 1.0 CG D:ASN805 3.7 103.0 1.0 CD D:GLN791 4.0 122.8 1.0 CA D:ASN805 4.2 103.0 1.0 NE2 D:GLN791 4.3 122.8 1.0 CD D:GLU808 4.3 90.3 1.0 N D:ASN805 4.4 103.0 1.0 CB D:ASN805 4.5 103.0 1.0 OG D:SER804 4.6 98.6 1.0 ND2 D:ASN805 4.7 103.0 1.0 C D:SER804 4.7 98.6 1.0 CG D:GLU788 4.7 115.4 1.0 O D:SER804 4.8 98.6 1.0 CE1 D:TYR799 5.0 118.4 1.0

M.Grieben, B.G.Saward, A.C.W.Pike, C.J.Schofield, E.P.Carpenter. Cryo-Em Structure of the Human TRPA1 Ion Channel in Complex with the Antagonist 3-60 To Be Published.