Atomistry » Calcium » PDB 7p9t-7po7 » 7pby
Atomistry »
  Calcium »
    PDB 7p9t-7po7 »
      7pby »

Calcium in PDB 7pby: Crystal Structure of CD73 in Complex with 4-Nitrocatechol in the Open Form

Enzymatic activity of Crystal Structure of CD73 in Complex with 4-Nitrocatechol in the Open Form

All present enzymatic activity of Crystal Structure of CD73 in Complex with 4-Nitrocatechol in the Open Form:
3.1.3.5;

Protein crystallography data

The structure of Crystal Structure of CD73 in Complex with 4-Nitrocatechol in the Open Form, PDB code: 7pby was solved by E.R.Scaletti, N.Strater, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 46.77 / 1.13
Space group P 21 21 2
Cell size a, b, c (Å), α, β, γ (°) 67.21, 131.645, 66.348, 90, 90, 90
R / Rfree (%) 12.8 / 14.5

Other elements in 7pby:

The structure of Crystal Structure of CD73 in Complex with 4-Nitrocatechol in the Open Form also contains other interesting chemical elements:

Zinc (Zn) 2 atoms

Calcium Binding Sites:

The binding sites of Calcium atom in the Crystal Structure of CD73 in Complex with 4-Nitrocatechol in the Open Form (pdb code 7pby). This binding sites where shown within 5.0 Angstroms radius around Calcium atom.
In total only one binding site of Calcium was determined in the Crystal Structure of CD73 in Complex with 4-Nitrocatechol in the Open Form, PDB code: 7pby:

Calcium binding site 1 out of 1 in 7pby

Go back to Calcium Binding Sites List in 7pby
Calcium binding site 1 out of 1 in the Crystal Structure of CD73 in Complex with 4-Nitrocatechol in the Open Form


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 1 of Crystal Structure of CD73 in Complex with 4-Nitrocatechol in the Open Form within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Ca603

b:16.3
occ:1.00
 O A:HOH776 2.3 24.8 1.0
O A:ASN213 2.3 16.1 1.0
O A:GLY298 2.3 18.0 1.0
O A:HOH886 2.4 19.1 1.0
OD2 A:ASP237 2.5 12.9 1.0
OD1 A:ASP237 2.5 14.6 1.0
O A:HOH1006 2.5 37.7 1.0
CG A:ASP237 2.8 12.3 1.0
C A:GLY298 3.4 16.4 1.0
C A:ASN213 3.5 15.0 1.0
CA A:GLY298 4.0 17.5 1.0
O A:GLY235 4.3 15.0 1.0
N A:LYS214 4.3 13.3 1.0
N A:ASN299 4.3 18.4 1.0
CA A:LYS214 4.3 13.2 1.0
CB A:ASP237 4.3 11.1 1.0
O A:HOH787 4.4 17.2 1.0
CA A:ASN213 4.4 16.4 1.0
CA A:ASN299 4.6 18.3 1.0
O A:ARG297 4.7 24.4 1.0
O A:HOH878 4.7 21.6 1.0
N A:ILE215 4.8 11.6 1.0
NH1 A:ARG273 4.8 37.8 1.0
CB A:ASN213 4.8 19.1 1.0
OD1 A:ASN299 4.9 32.0 1.0

Reference:

E.Scaletti, F.U.Huschmann, U.Mueller, M.S.Weiss, N.Strater. Substrate Binding Modes of Purine and Pyrimidine Nucleotides to Human Ecto-5'-Nucleotidase (CD73) and Inhibition By Their Bisphosphonic Acid Derivatives. Purinergic Signal 2021.
ISSN: ISSN 1573-9546
PubMed: 34403084
DOI: 10.1007/S11302-021-09802-W
Page generated: Fri Jul 19 02:50:23 2024

Last articles

Zn in 9JYW
Zn in 9IR4
Zn in 9IR3
Zn in 9GMX
Zn in 9GMW
Zn in 9JEJ
Zn in 9ERF
Zn in 9ERE
Zn in 9EGV
Zn in 9EGW
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy