Calcium in PDB 7rx2: AFTMEM16 in C22 Lipid Nanodiscs with MSP1E3 Scaffold Protein in the Presnece of CA2+

The binding sites of Calcium atom in the AFTMEM16 in C22 Lipid Nanodiscs with MSP1E3 Scaffold Protein in the Presnece of CA2+ (pdb code 7rx2). This binding sites where shown within 5.0 Angstroms radius around Calcium atom.
In total 4 binding sites of Calcium where determined in the AFTMEM16 in C22 Lipid Nanodiscs with MSP1E3 Scaffold Protein in the Presnece of CA2+, PDB code: 7rx2:
Jump to Calcium binding site number: 1; 2; 3; 4;

Calcium binding site 1 out of 4 in the AFTMEM16 in C22 Lipid Nanodiscs with MSP1E3 Scaffold Protein in the Presnece of CA2+


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 1 of AFTMEM16 in C22 Lipid Nanodiscs with MSP1E3 Scaffold Protein in the Presnece of CA2+ within 5.0Å range: probe atom residue distance (Å) B Occ B:Ca801 b:33.8 occ:1.00 OD1 B:ASP511 2.3 28.7 1.0 OE2 B:GLU445 2.4 54.9 1.0 OE2 B:GLU543 2.4 31.1 1.0 OE2 B:GLU514 2.4 29.3 1.0 OD2 B:ASP547 2.6 32.0 1.0 OD1 B:ASP547 2.9 32.0 1.0 CG B:ASP547 3.1 32.0 1.0 CG B:ASP511 3.2 28.7 1.0 CD B:GLU445 3.4 54.9 1.0 CD B:GLU543 3.6 31.1 1.0 CD B:GLU514 3.6 29.3 1.0 OE1 B:GLU445 3.8 54.9 1.0 OH B:TYR180 3.8 23.1 1.0 CB B:ASP511 3.8 28.7 1.0 CA B:ASP511 3.9 28.7 1.0 CG B:GLU543 4.1 31.1 1.0 OD2 B:ASP511 4.1 28.7 1.0 OE1 B:GLU514 4.2 29.3 1.0 O B:ASP511 4.5 28.7 1.0 CA B:CA802 4.5 46.0 1.0 OE1 B:GLU543 4.6 31.1 1.0 CB B:ASP547 4.6 32.0 1.0 CB B:GLU514 4.7 29.3 1.0 CG B:GLU514 4.7 29.3 1.0 CG B:GLU445 4.7 54.9 1.0 C B:ASP511 4.7 28.7 1.0 NZ B:LYS550 4.8 37.2 1.0 CZ B:TYR180 4.8 23.1 1.0 N B:ASP511 5.0 28.7 1.0

Calcium binding site 2 out of 4 in the AFTMEM16 in C22 Lipid Nanodiscs with MSP1E3 Scaffold Protein in the Presnece of CA2+


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 2 of AFTMEM16 in C22 Lipid Nanodiscs with MSP1E3 Scaffold Protein in the Presnece of CA2+ within 5.0Å range: probe atom residue distance (Å) B Occ B:Ca802 b:46.0 occ:1.00 OE1 B:GLU514 2.4 29.3 1.0 OE1 B:GLU543 2.4 31.1 1.0 OE1 B:GLU445 2.6 54.9 1.0 OE2 B:GLU543 2.8 31.1 1.0 CD B:GLU543 2.9 31.1 1.0 CD B:GLU514 3.3 29.3 1.0 OE2 B:GLU514 3.7 29.3 1.0 CD B:GLU445 3.7 54.9 1.0 OE2 B:GLU445 4.2 54.9 1.0 CA B:PHE442 4.4 57.6 1.0 CG B:GLU543 4.4 31.1 1.0 N B:PHE442 4.5 57.6 1.0 CA B:CA801 4.5 33.8 1.0 C B:GLY441 4.6 54.8 1.0 O B:GLY441 4.6 54.8 1.0 CG B:GLU514 4.6 29.3 1.0 OD1 B:ASN539 4.8 28.7 1.0 CB B:PHE442 4.8 57.6 1.0 O B:GLN438 4.9 44.3 1.0 ND2 B:ASN539 4.9 28.7 1.0 CB B:GLU445 4.9 54.9 1.0 CG B:GLU445 4.9 54.9 1.0

Calcium binding site 3 out of 4 in the AFTMEM16 in C22 Lipid Nanodiscs with MSP1E3 Scaffold Protein in the Presnece of CA2+


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 3 of AFTMEM16 in C22 Lipid Nanodiscs with MSP1E3 Scaffold Protein in the Presnece of CA2+ within 5.0Å range: probe atom residue distance (Å) B Occ A:Ca1502 b:33.8 occ:1.00 OD1 A:ASP511 2.3 28.7 1.0 OE2 A:GLU445 2.4 54.9 1.0 OE2 A:GLU543 2.4 31.1 1.0 OE2 A:GLU514 2.4 29.3 1.0 OD2 A:ASP547 2.6 32.0 1.0 OD1 A:ASP547 2.9 32.0 1.0 CG A:ASP547 3.1 32.0 1.0 CG A:ASP511 3.2 28.7 1.0 CD A:GLU445 3.4 54.9 1.0 CD A:GLU543 3.6 31.1 1.0 CD A:GLU514 3.6 29.3 1.0 OE1 A:GLU445 3.8 54.9 1.0 OH A:TYR180 3.8 23.1 1.0 CB A:ASP511 3.8 28.7 1.0 CA A:ASP511 3.9 28.7 1.0 CG A:GLU543 4.1 31.1 1.0 OD2 A:ASP511 4.1 28.7 1.0 OE1 A:GLU514 4.2 29.3 1.0 O A:ASP511 4.5 28.7 1.0 CA A:CA1503 4.5 46.0 1.0 OE1 A:GLU543 4.6 31.1 1.0 CB A:ASP547 4.6 32.0 1.0 CB A:GLU514 4.7 29.3 1.0 CG A:GLU514 4.7 29.3 1.0 CG A:GLU445 4.7 54.9 1.0 C A:ASP511 4.7 28.7 1.0 NZ A:LYS550 4.8 37.2 1.0 CZ A:TYR180 4.8 23.1 1.0 N A:ASP511 5.0 28.7 1.0

Calcium binding site 4 out of 4 in the AFTMEM16 in C22 Lipid Nanodiscs with MSP1E3 Scaffold Protein in the Presnece of CA2+


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 4 of AFTMEM16 in C22 Lipid Nanodiscs with MSP1E3 Scaffold Protein in the Presnece of CA2+ within 5.0Å range: probe atom residue distance (Å) B Occ A:Ca1503 b:46.0 occ:1.00 OE1 A:GLU514 2.4 29.3 1.0 OE1 A:GLU543 2.4 31.1 1.0 OE1 A:GLU445 2.6 54.9 1.0 OE2 A:GLU543 2.8 31.1 1.0 CD A:GLU543 2.9 31.1 1.0 CD A:GLU514 3.3 29.3 1.0 OE2 A:GLU514 3.7 29.3 1.0 CD A:GLU445 3.7 54.9 1.0 OE2 A:GLU445 4.2 54.9 1.0 CA A:PHE442 4.4 57.6 1.0 CG A:GLU543 4.4 31.1 1.0 N A:PHE442 4.5 57.6 1.0 CA A:CA1502 4.5 33.8 1.0 C A:GLY441 4.6 54.8 1.0 O A:GLY441 4.6 54.8 1.0 CG A:GLU514 4.6 29.3 1.0 OD1 A:ASN539 4.7 28.7 1.0 CB A:PHE442 4.8 57.6 1.0 O A:GLN438 4.9 44.3 1.0 ND2 A:ASN539 4.9 28.7 1.0 CB A:GLU445 4.9 54.9 1.0 CG A:GLU445 4.9 54.9 1.0

M.E.Falzone, Z.Feng, O.E.Alvarenga, Y.Pan, B.Lee, X.Cheng, E.Fortea, S.Scheuring, A.Accardi. TMEM16 Scramblases Thin the Membrane to Enable Lipid Scrambling. Nat Commun V. 13 2604 2022.
ISSN: ESSN 2041-1723
PubMed: 35562175
DOI: 10.1038/S41467-022-30300-Z