Calcium in PDB 7rxg: AFTMEM16 in C18 Lipid Nanodiscs with MSP1E3 Scaffold Protein in the Presence of CA2+, Full Dimer

The binding sites of Calcium atom in the AFTMEM16 in C18 Lipid Nanodiscs with MSP1E3 Scaffold Protein in the Presence of CA2+, Full Dimer (pdb code 7rxg). This binding sites where shown within 5.0 Angstroms radius around Calcium atom.
In total 4 binding sites of Calcium where determined in the AFTMEM16 in C18 Lipid Nanodiscs with MSP1E3 Scaffold Protein in the Presence of CA2+, Full Dimer, PDB code: 7rxg:
Jump to Calcium binding site number: 1; 2; 3; 4;

Calcium binding site 1 out of 4 in the AFTMEM16 in C18 Lipid Nanodiscs with MSP1E3 Scaffold Protein in the Presence of CA2+, Full Dimer


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 1 of AFTMEM16 in C18 Lipid Nanodiscs with MSP1E3 Scaffold Protein in the Presence of CA2+, Full Dimer within 5.0Å range: probe atom residue distance (Å) B Occ B:Ca801 b:18.5 occ:1.00 OE1 B:GLU543 2.4 19.1 1.0 OE2 B:GLU445 2.4 29.6 1.0 OD1 B:ASP511 2.6 18.7 1.0 O B:HOH2719 2.6 19.2 1.0 OE1 B:GLU514 2.7 17.7 1.0 OD1 B:ASP547 2.7 20.2 1.0 OD2 B:ASP547 2.7 20.2 1.0 H1 B:HOH2719 2.8 19.2 1.0 H2 B:HOH2719 3.0 19.2 1.0 CG B:ASP547 3.1 20.2 1.0 CD B:GLU445 3.2 29.6 1.0 CG B:ASP511 3.3 18.7 1.0 OE1 B:GLU445 3.3 29.6 1.0 CD B:GLU543 3.5 19.1 1.0 CD B:GLU514 3.5 17.7 1.0 H2 B:HOH2702 3.7 23.2 1.0 CB B:ASP511 3.9 18.7 1.0 NZ B:LYS550 3.9 23.0 1.0 OD2 B:ASP511 4.0 18.7 1.0 OE2 B:GLU514 4.0 17.7 1.0 OH B:TYR180 4.0 25.6 1.0 CA B:ASP511 4.1 18.7 1.0 CA B:CA802 4.1 25.4 1.0 CG B:GLU543 4.2 19.1 1.0 H1 B:HOH2702 4.3 23.2 1.0 O B:HOH2702 4.3 23.2 1.0 OE2 B:GLU543 4.5 19.1 1.0 CB B:ASP547 4.6 20.2 1.0 CG B:GLU445 4.6 29.6 1.0 CB B:GLU514 4.7 17.7 1.0 CG B:GLU514 4.7 17.7 1.0 O B:ASP511 4.9 18.7 1.0

Calcium binding site 2 out of 4 in the AFTMEM16 in C18 Lipid Nanodiscs with MSP1E3 Scaffold Protein in the Presence of CA2+, Full Dimer


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 2 of AFTMEM16 in C18 Lipid Nanodiscs with MSP1E3 Scaffold Protein in the Presence of CA2+, Full Dimer within 5.0Å range: probe atom residue distance (Å) B Occ B:Ca802 b:25.4 occ:1.00 OE2 B:GLU514 2.4 17.7 1.0 O B:HOH2710 2.5 23.7 1.0 OE1 B:GLU445 2.6 29.6 1.0 OE2 B:GLU543 2.7 19.1 1.0 OE1 B:GLU543 2.7 19.1 1.0 H1 B:HOH2710 2.8 23.7 1.0 CD B:GLU543 3.1 19.1 1.0 H2 B:HOH2710 3.2 23.7 1.0 CD B:GLU514 3.3 17.7 1.0 OE1 B:GLU514 3.4 17.7 1.0 H2 B:HOH2721 3.6 21.9 1.0 CD B:GLU445 3.8 29.6 1.0 H1 B:HOH2702 4.0 23.2 1.0 H1 B:HOH2721 4.1 21.9 1.0 N B:PHE442 4.1 29.2 1.0 CA B:CA801 4.1 18.5 1.0 CA B:PHE442 4.2 29.2 1.0 O B:HOH2702 4.2 23.2 1.0 O B:HOH2721 4.2 21.9 1.0 C B:GLY441 4.3 28.3 1.0 OE2 B:GLU445 4.4 29.6 1.0 H2 B:HOH2702 4.4 23.2 1.0 O B:GLY441 4.4 28.3 1.0 CG B:GLU543 4.6 19.1 1.0 CB B:PHE442 4.6 29.2 1.0 CG B:GLU514 4.7 17.7 1.0 OD1 B:ASN539 4.7 18.5 1.0 CB B:GLU445 4.7 29.6 1.0 CG B:GLU445 4.8 29.6 1.0 O B:GLN438 4.9 23.5 1.0 ND2 B:ASN539 5.0 18.5 1.0

Calcium binding site 3 out of 4 in the AFTMEM16 in C18 Lipid Nanodiscs with MSP1E3 Scaffold Protein in the Presence of CA2+, Full Dimer


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 3 of AFTMEM16 in C18 Lipid Nanodiscs with MSP1E3 Scaffold Protein in the Presence of CA2+, Full Dimer within 5.0Å range: probe atom residue distance (Å) B Occ A:Ca1103 b:18.5 occ:1.00 OE1 A:GLU543 2.4 19.1 1.0 OE2 A:GLU445 2.4 29.6 1.0 OD1 A:ASP511 2.6 18.7 1.0 O A:HOH2719 2.6 19.2 1.0 OE1 A:GLU514 2.7 17.7 1.0 OD1 A:ASP547 2.7 20.2 1.0 OD2 A:ASP547 2.7 20.2 1.0 H1 A:HOH2719 2.8 19.2 1.0 H2 A:HOH2719 3.0 19.2 1.0 CG A:ASP547 3.1 20.2 1.0 CD A:GLU445 3.2 29.6 1.0 CG A:ASP511 3.3 18.7 1.0 OE1 A:GLU445 3.3 29.6 1.0 CD A:GLU543 3.5 19.1 1.0 CD A:GLU514 3.5 17.7 1.0 H2 A:HOH2702 3.7 23.2 1.0 CB A:ASP511 3.9 18.7 1.0 NZ A:LYS550 3.9 23.0 1.0 OD2 A:ASP511 4.0 18.7 1.0 OE2 A:GLU514 4.0 17.7 1.0 OH A:TYR180 4.0 25.6 1.0 CA A:ASP511 4.1 18.7 1.0 CA A:CA1104 4.1 25.4 1.0 CG A:GLU543 4.2 19.1 1.0 H1 A:HOH2702 4.3 23.2 1.0 O A:HOH2702 4.3 23.2 1.0 OE2 A:GLU543 4.5 19.1 1.0 CB A:ASP547 4.6 20.2 1.0 CG A:GLU445 4.6 29.6 1.0 CB A:GLU514 4.7 17.7 1.0 CG A:GLU514 4.7 17.7 1.0 O A:ASP511 4.9 18.7 1.0

Calcium binding site 4 out of 4 in the AFTMEM16 in C18 Lipid Nanodiscs with MSP1E3 Scaffold Protein in the Presence of CA2+, Full Dimer


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 4 of AFTMEM16 in C18 Lipid Nanodiscs with MSP1E3 Scaffold Protein in the Presence of CA2+, Full Dimer within 5.0Å range: probe atom residue distance (Å) B Occ A:Ca1104 b:25.4 occ:1.00 OE2 A:GLU514 2.4 17.7 1.0 O A:HOH2710 2.5 23.7 1.0 OE1 A:GLU445 2.6 29.6 1.0 OE2 A:GLU543 2.7 19.1 1.0 OE1 A:GLU543 2.7 19.1 1.0 H1 A:HOH2710 2.8 23.7 1.0 CD A:GLU543 3.0 19.1 1.0 H2 A:HOH2710 3.2 23.7 1.0 CD A:GLU514 3.3 17.7 1.0 OE1 A:GLU514 3.4 17.7 1.0 H2 A:HOH2721 3.6 21.9 1.0 CD A:GLU445 3.8 29.6 1.0 H1 A:HOH2702 4.0 23.2 1.0 H1 A:HOH2721 4.1 21.9 1.0 N A:PHE442 4.1 29.2 1.0 CA A:CA1103 4.1 18.5 1.0 CA A:PHE442 4.2 29.2 1.0 O A:HOH2721 4.2 21.9 1.0 O A:HOH2702 4.2 23.2 1.0 C A:GLY441 4.3 28.3 1.0 OE2 A:GLU445 4.4 29.6 1.0 H2 A:HOH2702 4.4 23.2 1.0 O A:GLY441 4.4 28.3 1.0 CG A:GLU543 4.6 19.1 1.0 CB A:PHE442 4.6 29.2 1.0 CG A:GLU514 4.7 17.7 1.0 OD1 A:ASN539 4.7 18.5 1.0 CB A:GLU445 4.7 29.6 1.0 CG A:GLU445 4.8 29.6 1.0 O A:GLN438 4.9 23.5 1.0 ND2 A:ASN539 5.0 18.5 1.0

M.E.Falzone, Z.Feng, O.E.Alvarenga, Y.Pan, B.Lee, X.Cheng, E.Fortea, S.Scheuring, A.Accardi. TMEM16 Scramblases Thin the Membrane to Enable Lipid Scrambling. Nat Commun V. 13 2604 2022.
ISSN: ESSN 2041-1723
PubMed: 35562175
DOI: 10.1038/S41467-022-30300-Z