Atomistry » Calcium » PDB 7tci-7ubr » 7tci
Atomistry »
  Calcium »
    PDB 7tci-7ubr »
      7tci »

Calcium in PDB 7tci: Structure of Xenopus KCNQ1-Cam in Complex with ML277

Calcium Binding Sites:

Pages:

>>> Page 1 <<< Page 2, Binding sites: 11 - 12;

Binding sites:

The binding sites of Calcium atom in the Structure of Xenopus KCNQ1-Cam in Complex with ML277 (pdb code 7tci). This binding sites where shown within 5.0 Angstroms radius around Calcium atom.
In total 12 binding sites of Calcium where determined in the Structure of Xenopus KCNQ1-Cam in Complex with ML277, PDB code: 7tci:
Jump to Calcium binding site number: 1; 2; 3; 4; 5; 6; 7; 8; 9; 10;

Calcium binding site 1 out of 12 in 7tci

Go back to Calcium Binding Sites List in 7tci
Calcium binding site 1 out of 12 in the Structure of Xenopus KCNQ1-Cam in Complex with ML277


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 1 of Structure of Xenopus KCNQ1-Cam in Complex with ML277 within 5.0Å range:
probe atom residue distance (Å) B Occ
B:Ca901

b:149.6
occ:1.00
 O B:THR27 2.6 144.7 1.0
OD2 B:ASP25 2.7 147.5 1.0
C B:THR27 3.0 144.7 1.0
CB B:THR27 3.2 144.7 1.0
CG B:ASP25 3.6 147.5 1.0
CA B:THR27 3.6 144.7 1.0
CG2 B:THR27 3.6 144.7 1.0
N B:ILE28 3.7 140.6 1.0
OD1 B:ASP25 4.0 147.5 1.0
C B:ILE28 4.0 140.6 1.0
N B:THR29 4.0 138.0 1.0
CB B:THR29 4.1 138.0 1.0
OE1 B:GLU32 4.1 141.8 1.0
CA B:ILE28 4.1 140.6 1.0
N B:THR27 4.3 144.7 1.0
CG2 B:THR29 4.3 138.0 1.0
OG1 B:THR27 4.4 144.7 1.0
O B:ILE28 4.5 140.6 1.0
CA B:THR29 4.6 138.0 1.0
OE2 B:GLU32 4.7 141.8 1.0
CD B:GLU32 4.7 141.8 1.0
CB B:ASP25 4.8 147.5 1.0

Calcium binding site 2 out of 12 in 7tci

Go back to Calcium Binding Sites List in 7tci
Calcium binding site 2 out of 12 in the Structure of Xenopus KCNQ1-Cam in Complex with ML277


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 2 of Structure of Xenopus KCNQ1-Cam in Complex with ML277 within 5.0Å range:
probe atom residue distance (Å) B Occ
B:Ca902

b:134.9
occ:1.00
 OE2 B:GLU68 2.5 137.8 1.0
OD1 B:ASN61 2.5 129.2 1.0
ND2 B:ASN61 2.6 129.2 1.0
OD1 B:ASP59 2.6 126.1 1.0
OE1 B:GLU68 2.7 137.8 1.0
OD1 B:ASP57 2.8 130.4 1.0
CD B:GLU68 2.8 137.8 1.0
CG B:ASN61 2.8 129.2 1.0
O B:THR63 2.8 132.3 1.0
OD2 B:ASP59 2.9 126.1 1.0
CG B:ASP59 3.1 126.1 1.0
CG B:ASP57 3.8 130.4 1.0
C B:THR63 3.8 132.3 1.0
CG B:GLU68 4.1 137.8 1.0
OD2 B:ASP57 4.2 130.4 1.0
CB B:ASN61 4.2 129.2 1.0
N B:ASP65 4.3 141.3 1.0
OG1 B:THR63 4.4 132.3 1.0
CB B:ASP59 4.4 126.1 1.0
N B:ASN61 4.5 129.2 1.0
CB B:ASP65 4.5 141.3 1.0
N B:THR63 4.5 132.3 1.0
N B:ILE64 4.6 137.7 1.0
CA B:ILE64 4.6 137.7 1.0
N B:ASP59 4.7 126.1 1.0
CA B:THR63 4.7 132.3 1.0
C B:ILE64 4.8 137.7 1.0
N B:GLY60 4.8 125.5 1.0
N B:GLY62 4.9 131.3 1.0
CA B:ASN61 4.9 129.2 1.0

Calcium binding site 3 out of 12 in 7tci

Go back to Calcium Binding Sites List in 7tci
Calcium binding site 3 out of 12 in the Structure of Xenopus KCNQ1-Cam in Complex with ML277


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 3 of Structure of Xenopus KCNQ1-Cam in Complex with ML277 within 5.0Å range:
probe atom residue distance (Å) B Occ
B:Ca903

b:110.7
occ:1.00
 CA B:VAL137 2.9 98.8 1.0
ND2 B:ASN138 3.1 96.0 1.0
O B:GLN136 3.1 104.7 1.0
N B:ASN138 3.1 96.0 1.0
O B:ALA129 3.5 108.8 1.0
CG B:ASN138 3.5 96.0 1.0
C B:VAL137 3.5 98.8 1.0
OD1 B:ASN138 3.6 96.0 1.0
CA B:ASP130 3.7 113.4 1.0
CB B:VAL137 3.7 98.8 1.0
OD1 B:ASP132 3.7 118.5 1.0
N B:VAL137 3.8 98.8 1.0
C B:GLN136 3.8 104.7 1.0
CG2 B:VAL137 4.0 98.8 1.0
C B:ALA129 4.2 108.8 1.0
OD1 B:ASP134 4.3 115.3 1.0
N B:ASP130 4.3 113.4 1.0
CA B:ASN138 4.3 96.0 1.0
CB B:ASP130 4.3 113.4 1.0
CB B:ASN138 4.5 96.0 1.0
OD2 B:ASP134 4.5 115.3 1.0
N B:ILE131 4.6 116.5 1.0
C B:ASP130 4.6 113.4 1.0
O B:VAL137 4.7 98.8 1.0
CG B:ASP132 4.8 118.5 1.0
CG B:ASP134 4.8 115.3 1.0

Calcium binding site 4 out of 12 in 7tci

Go back to Calcium Binding Sites List in 7tci
Calcium binding site 4 out of 12 in the Structure of Xenopus KCNQ1-Cam in Complex with ML277


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 4 of Structure of Xenopus KCNQ1-Cam in Complex with ML277 within 5.0Å range:
probe atom residue distance (Å) B Occ
F:Ca901

b:149.6
occ:1.00
 O F:THR27 2.6 144.7 1.0
OD2 F:ASP25 2.7 147.5 1.0
C F:THR27 3.1 144.7 1.0
CB F:THR27 3.2 144.7 1.0
CG2 F:THR27 3.6 144.7 1.0
CG F:ASP25 3.6 147.5 1.0
CA F:THR27 3.7 144.7 1.0
N F:ILE28 3.8 140.6 1.0
OD1 F:ASP25 4.1 147.5 1.0
C F:ILE28 4.1 140.6 1.0
CB F:THR29 4.1 138.0 1.0
N F:THR29 4.1 138.0 1.0
OE1 F:GLU32 4.1 141.8 1.0
CA F:ILE28 4.2 140.6 1.0
CG2 F:THR29 4.3 138.0 1.0
N F:THR27 4.3 144.7 1.0
OG1 F:THR27 4.4 144.7 1.0
O F:ILE28 4.5 140.6 1.0
CA F:THR29 4.6 138.0 1.0
OE2 F:GLU32 4.7 141.8 1.0
CD F:GLU32 4.8 141.8 1.0
CB F:ASP25 4.8 147.5 1.0

Calcium binding site 5 out of 12 in 7tci

Go back to Calcium Binding Sites List in 7tci
Calcium binding site 5 out of 12 in the Structure of Xenopus KCNQ1-Cam in Complex with ML277


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 5 of Structure of Xenopus KCNQ1-Cam in Complex with ML277 within 5.0Å range:
probe atom residue distance (Å) B Occ
F:Ca902

b:134.9
occ:1.00
 OE2 F:GLU68 2.5 137.8 1.0
OD1 F:ASN61 2.5 129.2 1.0
ND2 F:ASN61 2.6 129.2 1.0
OD1 F:ASP59 2.6 126.1 1.0
OE1 F:GLU68 2.7 137.8 1.0
OD1 F:ASP57 2.8 130.4 1.0
CD F:GLU68 2.8 137.8 1.0
CG F:ASN61 2.8 129.2 1.0
O F:THR63 2.9 132.3 1.0
OD2 F:ASP59 2.9 126.1 1.0
CG F:ASP59 3.0 126.1 1.0
CG F:ASP57 3.8 130.4 1.0
C F:THR63 3.8 132.3 1.0
CG F:GLU68 4.1 137.8 1.0
OD2 F:ASP57 4.2 130.4 1.0
CB F:ASN61 4.2 129.2 1.0
N F:ASP65 4.4 141.3 1.0
OG1 F:THR63 4.4 132.3 1.0
CB F:ASP59 4.4 126.1 1.0
N F:ASN61 4.5 129.2 1.0
CB F:ASP65 4.5 141.3 1.0
N F:THR63 4.5 132.3 1.0
N F:ILE64 4.6 137.7 1.0
CA F:ILE64 4.6 137.7 1.0
N F:ASP59 4.7 126.1 1.0
CA F:THR63 4.7 132.3 1.0
C F:ILE64 4.8 137.7 1.0
N F:GLY60 4.8 125.5 1.0
N F:GLY62 4.9 131.3 1.0
CA F:ASN61 4.9 129.2 1.0

Calcium binding site 6 out of 12 in 7tci

Go back to Calcium Binding Sites List in 7tci
Calcium binding site 6 out of 12 in the Structure of Xenopus KCNQ1-Cam in Complex with ML277


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 6 of Structure of Xenopus KCNQ1-Cam in Complex with ML277 within 5.0Å range:
probe atom residue distance (Å) B Occ
F:Ca903

b:110.7
occ:1.00
 CA F:VAL137 2.9 98.8 1.0
O F:GLN136 3.1 104.7 1.0
N F:ASN138 3.1 96.0 1.0
ND2 F:ASN138 3.2 96.0 1.0
O F:ALA129 3.4 108.8 1.0
CG F:ASN138 3.5 96.0 1.0
C F:VAL137 3.5 98.8 1.0
CA F:ASP130 3.7 113.4 1.0
OD1 F:ASN138 3.7 96.0 1.0
CB F:VAL137 3.7 98.8 1.0
OD1 F:ASP132 3.7 118.5 1.0
N F:VAL137 3.8 98.8 1.0
C F:GLN136 3.8 104.7 1.0
CG2 F:VAL137 3.9 98.8 1.0
C F:ALA129 4.1 108.8 1.0
N F:ASP130 4.3 113.4 1.0
OD1 F:ASP134 4.3 115.3 1.0
CB F:ASP130 4.3 113.4 1.0
CA F:ASN138 4.4 96.0 1.0
OD2 F:ASP134 4.5 115.3 1.0
CB F:ASN138 4.5 96.0 1.0
N F:ILE131 4.5 116.5 1.0
C F:ASP130 4.6 113.4 1.0
CG F:ASP132 4.8 118.5 1.0
O F:VAL137 4.8 98.8 1.0
CG F:ASP134 4.8 115.3 1.0
OD2 F:ASP132 5.0 118.5 1.0

Calcium binding site 7 out of 12 in 7tci

Go back to Calcium Binding Sites List in 7tci
Calcium binding site 7 out of 12 in the Structure of Xenopus KCNQ1-Cam in Complex with ML277


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 7 of Structure of Xenopus KCNQ1-Cam in Complex with ML277 within 5.0Å range:
probe atom residue distance (Å) B Occ
D:Ca901

b:149.6
occ:1.00
 O D:THR27 2.6 144.7 1.0
OD2 D:ASP25 2.7 147.5 1.0
C D:THR27 3.1 144.7 1.0
CB D:THR27 3.2 144.7 1.0
CG2 D:THR27 3.6 144.7 1.0
CG D:ASP25 3.6 147.5 1.0
CA D:THR27 3.7 144.7 1.0
N D:ILE28 3.8 140.6 1.0
C D:ILE28 4.1 140.6 1.0
OD1 D:ASP25 4.1 147.5 1.0
CB D:THR29 4.1 138.0 1.0
N D:THR29 4.1 138.0 1.0
OE1 D:GLU32 4.1 141.8 1.0
CA D:ILE28 4.2 140.6 1.0
CG2 D:THR29 4.3 138.0 1.0
N D:THR27 4.3 144.7 1.0
OG1 D:THR27 4.4 144.7 1.0
O D:ILE28 4.5 140.6 1.0
CA D:THR29 4.6 138.0 1.0
OE2 D:GLU32 4.7 141.8 1.0
CD D:GLU32 4.7 141.8 1.0
CB D:ASP25 4.8 147.5 1.0

Calcium binding site 8 out of 12 in 7tci

Go back to Calcium Binding Sites List in 7tci
Calcium binding site 8 out of 12 in the Structure of Xenopus KCNQ1-Cam in Complex with ML277


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 8 of Structure of Xenopus KCNQ1-Cam in Complex with ML277 within 5.0Å range:
probe atom residue distance (Å) B Occ
D:Ca902

b:134.9
occ:1.00
 OE2 D:GLU68 2.5 137.8 1.0
OD1 D:ASN61 2.5 129.2 1.0
ND2 D:ASN61 2.6 129.2 1.0
OD1 D:ASP59 2.6 126.1 1.0
OE1 D:GLU68 2.7 137.8 1.0
OD1 D:ASP57 2.8 130.4 1.0
CD D:GLU68 2.8 137.8 1.0
CG D:ASN61 2.8 129.2 1.0
O D:THR63 2.9 132.3 1.0
OD2 D:ASP59 2.9 126.1 1.0
CG D:ASP59 3.1 126.1 1.0
CG D:ASP57 3.8 130.4 1.0
C D:THR63 3.8 132.3 1.0
CG D:GLU68 4.1 137.8 1.0
OD2 D:ASP57 4.2 130.4 1.0
CB D:ASN61 4.2 129.2 1.0
N D:ASP65 4.3 141.3 1.0
OG1 D:THR63 4.4 132.3 1.0
CB D:ASP59 4.5 126.1 1.0
N D:ASN61 4.5 129.2 1.0
CB D:ASP65 4.5 141.3 1.0
N D:THR63 4.5 132.3 1.0
N D:ILE64 4.6 137.7 1.0
CA D:ILE64 4.6 137.7 1.0
N D:ASP59 4.7 126.1 1.0
CA D:THR63 4.7 132.3 1.0
C D:ILE64 4.8 137.7 1.0
N D:GLY60 4.8 125.5 1.0
N D:GLY62 4.9 131.3 1.0
CA D:ASN61 4.9 129.2 1.0

Calcium binding site 9 out of 12 in 7tci

Go back to Calcium Binding Sites List in 7tci
Calcium binding site 9 out of 12 in the Structure of Xenopus KCNQ1-Cam in Complex with ML277


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 9 of Structure of Xenopus KCNQ1-Cam in Complex with ML277 within 5.0Å range:
probe atom residue distance (Å) B Occ
D:Ca903

b:110.7
occ:1.00
 CA D:VAL137 2.9 98.8 1.0
O D:GLN136 3.1 104.7 1.0
N D:ASN138 3.1 96.0 1.0
ND2 D:ASN138 3.1 96.0 1.0
O D:ALA129 3.4 108.8 1.0
CG D:ASN138 3.5 96.0 1.0
C D:VAL137 3.5 98.8 1.0
OD1 D:ASN138 3.7 96.0 1.0
CA D:ASP130 3.7 113.4 1.0
CB D:VAL137 3.7 98.8 1.0
OD1 D:ASP132 3.7 118.5 1.0
N D:VAL137 3.8 98.8 1.0
C D:GLN136 3.8 104.7 1.0
CG2 D:VAL137 3.9 98.8 1.0
C D:ALA129 4.1 108.8 1.0
OD1 D:ASP134 4.3 115.3 1.0
N D:ASP130 4.3 113.4 1.0
CB D:ASP130 4.3 113.4 1.0
CA D:ASN138 4.4 96.0 1.0
CB D:ASN138 4.5 96.0 1.0
OD2 D:ASP134 4.5 115.3 1.0
N D:ILE131 4.5 116.5 1.0
C D:ASP130 4.6 113.4 1.0
CG D:ASP132 4.8 118.5 1.0
O D:VAL137 4.8 98.8 1.0
CG D:ASP134 4.8 115.3 1.0
OD2 D:ASP132 5.0 118.5 1.0

Calcium binding site 10 out of 12 in 7tci

Go back to Calcium Binding Sites List in 7tci
Calcium binding site 10 out of 12 in the Structure of Xenopus KCNQ1-Cam in Complex with ML277


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 10 of Structure of Xenopus KCNQ1-Cam in Complex with ML277 within 5.0Å range:
probe atom residue distance (Å) B Occ
H:Ca901

b:149.6
occ:1.00
 O H:THR27 2.6 144.7 1.0
OD2 H:ASP25 2.7 147.5 1.0
C H:THR27 3.1 144.7 1.0
CB H:THR27 3.2 144.7 1.0
CG2 H:THR27 3.6 144.7 1.0
CG H:ASP25 3.6 147.5 1.0
CA H:THR27 3.7 144.7 1.0
N H:ILE28 3.8 140.6 1.0
OD1 H:ASP25 4.1 147.5 1.0
C H:ILE28 4.1 140.6 1.0
CB H:THR29 4.1 138.0 1.0
N H:THR29 4.1 138.0 1.0
OE1 H:GLU32 4.1 141.8 1.0
CA H:ILE28 4.2 140.6 1.0
CG2 H:THR29 4.3 138.0 1.0
N H:THR27 4.3 144.7 1.0
OG1 H:THR27 4.4 144.7 1.0
O H:ILE28 4.5 140.6 1.0
CA H:THR29 4.6 138.0 1.0
OE2 H:GLU32 4.7 141.8 1.0
CD H:GLU32 4.8 141.8 1.0
CB H:ASP25 4.8 147.5 1.0

Reference:

K.Willegems, J.Eldstrom, E.Kyriakis, F.Ataei, H.Sahakyan, Y.Dou, S.Russo, F.Van Petegem, D.Fedida. Structural and Electrophysiological Basis For the Modulation of KCNQ1 Channel Currents By ML277. Nat Commun V. 13 3760 2022.
ISSN: ESSN 2041-1723
PubMed: 35768468
DOI: 10.1038/S41467-022-31526-7
Page generated: Thu Jul 10 01:19:51 2025

Last articles

Fe in 2YXO
Fe in 2YRS
Fe in 2YXC
Fe in 2YNM
Fe in 2YVJ
Fe in 2YP1
Fe in 2YU2
Fe in 2YU1
Fe in 2YQB
Fe in 2YOO
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy