Calcium in PDB 7uhg: Human L-Type Voltage-Gated Calcium Channel CAV1.3 at 3.0 Angstrom Resolution

The binding sites of Calcium atom in the Human L-Type Voltage-Gated Calcium Channel CAV1.3 at 3.0 Angstrom Resolution (pdb code 7uhg). This binding sites where shown within 5.0 Angstroms radius around Calcium atom.
In total 2 binding sites of Calcium where determined in the Human L-Type Voltage-Gated Calcium Channel CAV1.3 at 3.0 Angstrom Resolution, PDB code: 7uhg:
Jump to Calcium binding site number: 1; 2;

Calcium binding site 1 out of 2 in the Human L-Type Voltage-Gated Calcium Channel CAV1.3 at 3.0 Angstrom Resolution


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 1 of Human L-Type Voltage-Gated Calcium Channel CAV1.3 at 3.0 Angstrom Resolution within 5.0Å range: probe atom residue distance (Å) B Occ A:Ca2201 b:11.4 occ:1.00 OE2 A:GLU364 2.5 4.9 1.0 OE1 A:GLU1101 2.5 2.1 1.0 OE1 A:GLU705 2.7 3.3 1.0 OE1 A:GLU364 2.8 4.9 1.0 OE2 A:GLU1101 2.9 2.1 1.0 CD A:GLU364 3.0 4.9 1.0 CD A:GLU1101 3.1 2.1 1.0 O A:GLY1405 3.4 2.5 1.0 O A:GLU1406 3.7 4.6 1.0 CD A:GLU705 3.9 3.3 1.0 OE2 A:GLU705 4.3 3.3 1.0 CA A:GLU1406 4.4 4.6 1.0 O A:PHE1100 4.4 3.1 1.0 C A:GLU1406 4.5 4.6 1.0 CG A:GLU364 4.5 4.9 1.0 C A:GLY1405 4.5 2.5 1.0 CG A:GLU1101 4.6 2.1 1.0 OE2 A:GLU1406 4.6 4.6 1.0 CD A:GLU1406 4.8 4.6 1.0 O A:MET363 4.8 9.4 1.0 CA A:GLU705 4.8 3.3 1.0 OE1 A:GLU1406 4.9 4.6 1.0 N A:GLU1406 5.0 4.6 1.0

Calcium binding site 2 out of 2 in the Human L-Type Voltage-Gated Calcium Channel CAV1.3 at 3.0 Angstrom Resolution


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 2 of Human L-Type Voltage-Gated Calcium Channel CAV1.3 at 3.0 Angstrom Resolution within 5.0Å range: probe atom residue distance (Å) B Occ D:Ca1203 b:21.5 occ:1.00 OG D:SER263 2.4 13.3 1.0 OG1 D:THR331 2.4 20.4 1.0 OD2 A:ASP153 2.5 17.2 1.0 OG D:SER261 2.6 21.8 1.0 CB D:SER263 3.4 13.3 1.0 CG A:ASP153 3.5 17.2 1.0 CB D:SER261 3.5 21.8 1.0 CB D:THR331 3.7 20.4 1.0 OD1 A:ASP153 3.9 17.2 1.0 N D:SER263 4.1 13.3 1.0 OD2 D:ASP259 4.2 20.4 1.0 CA D:SER263 4.3 13.3 1.0 CG2 D:THR331 4.4 20.4 1.0 N D:THR331 4.7 20.4 1.0 OD1 D:ASP363 4.8 9.2 1.0 CA D:THR331 4.8 20.4 1.0 CA D:SER261 4.8 21.8 1.0 OD1 D:ASP259 4.8 20.4 1.0 CB A:ASP153 4.8 17.2 1.0 N D:GLY262 4.9 16.6 1.0 C D:SER261 4.9 21.8 1.0 CG D:ASP259 4.9 20.4 1.0 O D:GLY364 5.0 16.0 1.0

X.Yao, S.Gao, N.Yan. Structural Basis For Pore Blockade of Human Voltage-Gated Calcium Channel Ca V 1.3 By Motion Sickness Drug Cinnarizine. Cell Res. V. 32 946 2022.
ISSN: ISSN 1001-0602
PubMed: 35477996
DOI: 10.1038/S41422-022-00663-5