Calcium in PDB 7ukh: Human KV4.2-KCHIP2-DPP6 Channel Complex in An Open State, Intracellular Region

The structure of Human KV4.2-KCHIP2-DPP6 Channel Complex in An Open State, Intracellular Region also contains other interesting chemical elements:

Zinc

(Zn)

4 atoms

Pages:

>>> Page 1 <<< Page 2, Binding sites: 11 - 12;

Binding sites:

The binding sites of Calcium atom in the Human KV4.2-KCHIP2-DPP6 Channel Complex in An Open State, Intracellular Region (pdb code 7ukh). This binding sites where shown within 5.0 Angstroms radius around Calcium atom.
In total 12 binding sites of Calcium where determined in the Human KV4.2-KCHIP2-DPP6 Channel Complex in An Open State, Intracellular Region, PDB code: 7ukh:
Jump to Calcium binding site number: 1; 2; 3; 4; 5; 6; 7; 8; 9; 10;

Calcium binding site 1 out of 12 in the Human KV4.2-KCHIP2-DPP6 Channel Complex in An Open State, Intracellular Region


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 1 of Human KV4.2-KCHIP2-DPP6 Channel Complex in An Open State, Intracellular Region within 5.0Å range: probe atom residue distance (Å) B Occ I:Ca901 b:40.2 occ:1.00 OD1 I:ASP135 2.4 38.6 1.0 O I:SER141 2.5 34.0 1.0 OD2 I:ASP146 2.5 26.4 1.0 OD1 I:ASN137 2.5 45.4 1.0 OD1 I:ASP139 2.6 41.5 1.0 OD2 I:ASP139 2.6 41.5 1.0 OD1 I:ASP146 2.6 26.4 1.0 CG I:ASP146 2.8 26.4 1.0 CG I:ASP139 2.9 41.5 1.0 CG I:ASN137 3.5 45.4 1.0 CG I:ASP135 3.5 38.6 1.0 C I:SER141 3.7 34.0 1.0 ND2 I:ASN137 3.8 45.4 1.0 CA I:VAL142 4.1 26.3 1.0 N I:SER143 4.1 23.8 1.0 CB I:ASP146 4.2 26.4 1.0 CA I:ASP135 4.2 38.6 1.0 OD2 I:ASP135 4.3 38.6 1.0 CB I:ASP135 4.3 38.6 1.0 N I:VAL142 4.3 26.3 1.0 OG I:SER143 4.4 23.8 1.0 CB I:ASP139 4.4 41.5 1.0 C I:ASP135 4.6 38.6 1.0 C I:VAL142 4.6 26.3 1.0 N I:THR136 4.6 43.7 1.0 N I:ASN137 4.7 45.4 1.0 CA I:SER141 4.8 34.0 1.0 CB I:ASN137 4.9 45.4 1.0 N I:ASP139 4.9 41.5 1.0 N I:SER141 4.9 34.0 1.0 CB I:SER143 4.9 23.8 1.0

Calcium binding site 2 out of 12 in the Human KV4.2-KCHIP2-DPP6 Channel Complex in An Open State, Intracellular Region


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 2 of Human KV4.2-KCHIP2-DPP6 Channel Complex in An Open State, Intracellular Region within 5.0Å range: probe atom residue distance (Å) B Occ I:Ca902 b:66.2 occ:1.00 OD1 I:ASN173 2.3 65.1 1.0 O I:CYS177 2.3 69.1 1.0 OD1 I:ASP171 2.4 61.8 1.0 OE2 I:GLU182 2.4 63.0 1.0 OE1 I:GLU182 2.4 63.0 1.0 OD1 I:ASP175 2.5 67.8 1.0 CD I:GLU182 2.7 63.0 1.0 CG I:ASN173 3.2 65.1 1.0 CG I:ASP175 3.3 67.8 1.0 ND2 I:ASN173 3.4 65.1 1.0 CG I:ASP171 3.4 61.8 1.0 C I:CYS177 3.5 69.1 1.0 OD2 I:ASP175 3.8 67.8 1.0 SG I:CYS177 4.0 69.1 1.0 OD2 I:ASP171 4.1 61.8 1.0 CG I:GLU182 4.2 63.0 1.0 N I:CYS177 4.3 69.1 1.0 N I:ILE178 4.4 67.6 1.0 CB I:ASP171 4.4 61.8 1.0 CA I:CYS177 4.4 69.1 1.0 CA I:ASP171 4.4 61.8 1.0 CA I:ILE178 4.5 67.6 1.0 CB I:ASP175 4.5 67.8 1.0 N I:ASN173 4.5 65.1 1.0 CB I:ASN173 4.5 65.1 1.0 CG2 I:THR179 4.5 67.2 1.0 N I:ASP175 4.6 67.8 1.0 N I:THR179 4.6 67.2 1.0 N I:LEU172 4.7 58.9 1.0 C I:ASP171 4.7 61.8 1.0 CB I:CYS177 4.9 69.1 1.0 N I:LYS174 4.9 63.3 1.0 N I:GLY176 4.9 67.1 1.0 CA I:ASN173 4.9 65.1 1.0

Calcium binding site 3 out of 12 in the Human KV4.2-KCHIP2-DPP6 Channel Complex in An Open State, Intracellular Region


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 3 of Human KV4.2-KCHIP2-DPP6 Channel Complex in An Open State, Intracellular Region within 5.0Å range: probe atom residue distance (Å) B Occ I:Ca903 b:83.1 occ:1.00 OD1 I:ASP219 2.2 79.6 1.0 CG I:ASP219 2.4 79.6 1.0 O I:VAL225 2.4 74.7 1.0 OD1 I:ASP223 2.4 81.2 1.0 OE2 I:GLU230 2.4 78.2 1.0 OE1 I:GLU230 2.4 78.2 1.0 OD1 I:ASN221 2.4 82.2 1.0 OD2 I:ASP219 2.4 79.6 1.0 CD I:GLU230 2.7 78.2 1.0 CG I:ASP223 3.3 81.2 1.0 CB I:ASP219 3.5 79.6 1.0 OD2 I:ASP223 3.5 81.2 1.0 CG I:ASN221 3.6 82.2 1.0 C I:VAL225 3.6 74.7 1.0 CA I:ASP219 3.8 79.6 1.0 N I:ARG220 4.0 81.2 1.0 ND2 I:ASN221 4.1 82.2 1.0 CG I:GLU230 4.2 78.2 1.0 N I:ASN221 4.2 82.2 1.0 CA I:VAL226 4.2 72.7 1.0 N I:ASP223 4.3 81.2 1.0 N I:VAL226 4.3 72.7 1.0 N I:LYS222 4.3 82.3 1.0 C I:ASP219 4.4 79.6 1.0 N I:VAL225 4.5 74.7 1.0 CG1 I:VAL225 4.6 74.7 1.0 CA I:VAL225 4.6 74.7 1.0 CB I:ASP223 4.6 81.2 1.0 N I:THR227 4.7 74.5 1.0 OG1 I:THR227 4.7 74.5 1.0 CB I:ASN221 4.8 82.2 1.0 CB I:GLU230 4.8 78.2 1.0 CA I:ASN221 4.8 82.2 1.0 C I:ASN221 4.9 82.2 1.0 C I:VAL226 4.9 72.7 1.0 CA I:ASP223 5.0 81.2 1.0

Calcium binding site 4 out of 12 in the Human KV4.2-KCHIP2-DPP6 Channel Complex in An Open State, Intracellular Region


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 4 of Human KV4.2-KCHIP2-DPP6 Channel Complex in An Open State, Intracellular Region within 5.0Å range: probe atom residue distance (Å) B Occ J:Ca901 b:38.1 occ:1.00 OD1 J:ASP135 2.4 39.1 1.0 O J:SER141 2.5 34.4 1.0 OD2 J:ASP146 2.5 26.4 1.0 OD1 J:ASN137 2.5 45.4 1.0 OD1 J:ASP139 2.6 42.2 1.0 OD2 J:ASP139 2.6 42.2 1.0 OD1 J:ASP146 2.6 26.4 1.0 CG J:ASP146 2.8 26.4 1.0 CG J:ASP139 2.9 42.2 1.0 CG J:ASN137 3.5 45.4 1.0 CG J:ASP135 3.5 39.1 1.0 C J:SER141 3.7 34.4 1.0 ND2 J:ASN137 3.8 45.4 1.0 CA J:VAL142 4.1 26.7 1.0 N J:SER143 4.1 24.0 1.0 CB J:ASP146 4.2 26.4 1.0 CA J:ASP135 4.2 39.1 1.0 OD2 J:ASP135 4.3 39.1 1.0 CB J:ASP135 4.3 39.1 1.0 N J:VAL142 4.3 26.7 1.0 OG J:SER143 4.4 24.0 1.0 CB J:ASP139 4.4 42.2 1.0 C J:ASP135 4.6 39.1 1.0 C J:VAL142 4.6 26.7 1.0 N J:THR136 4.6 43.9 1.0 N J:ASN137 4.7 45.4 1.0 CA J:SER141 4.8 34.4 1.0 CB J:ASN137 4.9 45.4 1.0 N J:ASP139 4.9 42.2 1.0 N J:SER141 4.9 34.4 1.0 CB J:SER143 4.9 24.0 1.0

Calcium binding site 5 out of 12 in the Human KV4.2-KCHIP2-DPP6 Channel Complex in An Open State, Intracellular Region


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 5 of Human KV4.2-KCHIP2-DPP6 Channel Complex in An Open State, Intracellular Region within 5.0Å range: probe atom residue distance (Å) B Occ J:Ca902 b:64.5 occ:1.00 OD1 J:ASN173 2.3 64.0 1.0 O J:CYS177 2.3 68.6 1.0 OD1 J:ASP171 2.4 61.1 1.0 OE2 J:GLU182 2.4 62.4 1.0 OE1 J:GLU182 2.4 62.4 1.0 OD1 J:ASP175 2.5 66.7 1.0 CD J:GLU182 2.7 62.4 1.0 CG J:ASN173 3.2 64.0 1.0 CG J:ASP175 3.3 66.7 1.0 ND2 J:ASN173 3.4 64.0 1.0 CG J:ASP171 3.4 61.1 1.0 C J:CYS177 3.5 68.6 1.0 OD2 J:ASP175 3.8 66.7 1.0 SG J:CYS177 4.0 68.6 1.0 OD2 J:ASP171 4.1 61.1 1.0 CG J:GLU182 4.2 62.4 1.0 N J:CYS177 4.3 68.6 1.0 N J:ILE178 4.4 67.0 1.0 CB J:ASP171 4.4 61.1 1.0 CA J:CYS177 4.4 68.6 1.0 CA J:ASP171 4.4 61.1 1.0 CA J:ILE178 4.5 67.0 1.0 CB J:ASP175 4.5 66.7 1.0 N J:ASN173 4.5 64.0 1.0 CB J:ASN173 4.5 64.0 1.0 CG2 J:THR179 4.5 66.7 1.0 N J:ASP175 4.6 66.7 1.0 N J:THR179 4.6 66.7 1.0 N J:LEU172 4.7 58.2 1.0 C J:ASP171 4.7 61.1 1.0 CB J:CYS177 4.9 68.6 1.0 N J:LYS174 4.9 62.3 1.0 N J:GLY176 4.9 66.5 1.0 CA J:ASN173 4.9 64.0 1.0

Calcium binding site 6 out of 12 in the Human KV4.2-KCHIP2-DPP6 Channel Complex in An Open State, Intracellular Region


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 6 of Human KV4.2-KCHIP2-DPP6 Channel Complex in An Open State, Intracellular Region within 5.0Å range: probe atom residue distance (Å) B Occ J:Ca903 b:82.8 occ:1.00 OD1 J:ASP219 2.2 80.2 1.0 CG J:ASP219 2.4 80.2 1.0 O J:VAL225 2.4 74.9 1.0 OD1 J:ASP223 2.4 81.8 1.0 OE2 J:GLU230 2.4 78.2 1.0 OE1 J:GLU230 2.4 78.2 1.0 OD1 J:ASN221 2.4 82.6 1.0 OD2 J:ASP219 2.4 80.2 1.0 CD J:GLU230 2.7 78.2 1.0 CG J:ASP223 3.3 81.8 1.0 CB J:ASP219 3.5 80.2 1.0 OD2 J:ASP223 3.5 81.8 1.0 CG J:ASN221 3.6 82.6 1.0 C J:VAL225 3.6 74.9 1.0 CA J:ASP219 3.8 80.2 1.0 N J:ARG220 4.0 81.1 1.0 ND2 J:ASN221 4.1 82.6 1.0 CG J:GLU230 4.2 78.2 1.0 N J:ASN221 4.2 82.6 1.0 CA J:VAL226 4.2 72.9 1.0 N J:ASP223 4.3 81.8 1.0 N J:VAL226 4.3 72.9 1.0 N J:LYS222 4.3 82.9 1.0 C J:ASP219 4.4 80.2 1.0 N J:VAL225 4.5 74.9 1.0 CG1 J:VAL225 4.6 74.9 1.0 CA J:VAL225 4.6 74.9 1.0 CB J:ASP223 4.6 81.8 1.0 N J:THR227 4.7 74.4 1.0 OG1 J:THR227 4.7 74.4 1.0 CB J:ASN221 4.8 82.6 1.0 CB J:GLU230 4.8 78.2 1.0 CA J:ASN221 4.8 82.6 1.0 C J:ASN221 4.9 82.6 1.0 C J:VAL226 4.9 72.9 1.0 CA J:ASP223 5.0 81.8 1.0

Calcium binding site 7 out of 12 in the Human KV4.2-KCHIP2-DPP6 Channel Complex in An Open State, Intracellular Region


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 7 of Human KV4.2-KCHIP2-DPP6 Channel Complex in An Open State, Intracellular Region within 5.0Å range: probe atom residue distance (Å) B Occ K:Ca901 b:38.2 occ:1.00 OD1 K:ASP135 2.4 39.3 1.0 O K:SER141 2.5 34.7 1.0 OD2 K:ASP146 2.5 26.8 1.0 OD1 K:ASN137 2.5 45.1 1.0 OD1 K:ASP139 2.6 42.1 1.0 OD2 K:ASP139 2.6 42.1 1.0 OD1 K:ASP146 2.6 26.8 1.0 CG K:ASP146 2.8 26.8 1.0 CG K:ASP139 2.9 42.1 1.0 CG K:ASN137 3.5 45.1 1.0 CG K:ASP135 3.5 39.3 1.0 C K:SER141 3.7 34.7 1.0 ND2 K:ASN137 3.8 45.1 1.0 CA K:VAL142 4.1 27.3 1.0 N K:SER143 4.1 24.6 1.0 CB K:ASP146 4.2 26.8 1.0 CA K:ASP135 4.2 39.3 1.0 OD2 K:ASP135 4.3 39.3 1.0 CB K:ASP135 4.3 39.3 1.0 N K:VAL142 4.3 27.3 1.0 OG K:SER143 4.4 24.6 1.0 CB K:ASP139 4.4 42.1 1.0 C K:ASP135 4.6 39.3 1.0 C K:VAL142 4.6 27.3 1.0 N K:THR136 4.6 43.6 1.0 N K:ASN137 4.7 45.1 1.0 CA K:SER141 4.8 34.7 1.0 CB K:ASN137 4.9 45.1 1.0 N K:ASP139 4.9 42.1 1.0 N K:SER141 4.9 34.7 1.0 CB K:SER143 4.9 24.6 1.0

Calcium binding site 8 out of 12 in the Human KV4.2-KCHIP2-DPP6 Channel Complex in An Open State, Intracellular Region


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 8 of Human KV4.2-KCHIP2-DPP6 Channel Complex in An Open State, Intracellular Region within 5.0Å range: probe atom residue distance (Å) B Occ K:Ca902 b:65.5 occ:1.00 OD1 K:ASN173 2.3 64.6 1.0 O K:CYS177 2.3 69.3 1.0 OD1 K:ASP171 2.4 61.4 1.0 OE2 K:GLU182 2.4 63.3 1.0 OE1 K:GLU182 2.4 63.3 1.0 OD1 K:ASP175 2.5 67.7 1.0 CD K:GLU182 2.7 63.3 1.0 CG K:ASN173 3.2 64.6 1.0 CG K:ASP175 3.3 67.7 1.0 ND2 K:ASN173 3.4 64.6 1.0 CG K:ASP171 3.4 61.4 1.0 C K:CYS177 3.5 69.3 1.0 OD2 K:ASP175 3.8 67.7 1.0 SG K:CYS177 4.0 69.3 1.0 OD2 K:ASP171 4.1 61.4 1.0 CG K:GLU182 4.2 63.3 1.0 N K:CYS177 4.3 69.3 1.0 N K:ILE178 4.4 67.5 1.0 CB K:ASP171 4.4 61.4 1.0 CA K:CYS177 4.4 69.3 1.0 CA K:ASP171 4.4 61.4 1.0 CA K:ILE178 4.5 67.5 1.0 CB K:ASP175 4.5 67.7 1.0 N K:ASN173 4.5 64.6 1.0 CB K:ASN173 4.5 64.6 1.0 CG2 K:THR179 4.5 67.5 1.0 N K:ASP175 4.6 67.7 1.0 N K:THR179 4.6 67.5 1.0 N K:LEU172 4.7 59.3 1.0 C K:ASP171 4.7 61.4 1.0 CB K:CYS177 4.9 69.3 1.0 N K:LYS174 4.9 63.0 1.0 N K:GLY176 4.9 67.3 1.0 CA K:ASN173 4.9 64.6 1.0

Calcium binding site 9 out of 12 in the Human KV4.2-KCHIP2-DPP6 Channel Complex in An Open State, Intracellular Region


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 9 of Human KV4.2-KCHIP2-DPP6 Channel Complex in An Open State, Intracellular Region within 5.0Å range: probe atom residue distance (Å) B Occ K:Ca903 b:84.2 occ:1.00 OD1 K:ASP219 2.2 80.8 1.0 CG K:ASP219 2.4 80.8 1.0 O K:VAL225 2.4 75.6 1.0 OD1 K:ASP223 2.4 82.4 1.0 OE2 K:GLU230 2.4 78.9 1.0 OE1 K:GLU230 2.4 78.9 1.0 OD1 K:ASN221 2.4 83.2 1.0 OD2 K:ASP219 2.4 80.8 1.0 CD K:GLU230 2.7 78.9 1.0 CG K:ASP223 3.3 82.4 1.0 CB K:ASP219 3.5 80.8 1.0 OD2 K:ASP223 3.5 82.4 1.0 CG K:ASN221 3.6 83.2 1.0 C K:VAL225 3.6 75.6 1.0 CA K:ASP219 3.8 80.8 1.0 N K:ARG220 4.0 81.9 1.0 ND2 K:ASN221 4.1 83.2 1.0 CG K:GLU230 4.2 78.9 1.0 N K:ASN221 4.2 83.2 1.0 CA K:VAL226 4.2 73.3 1.0 N K:ASP223 4.3 82.4 1.0 N K:VAL226 4.3 73.3 1.0 N K:LYS222 4.3 83.4 1.0 C K:ASP219 4.4 80.8 1.0 N K:VAL225 4.5 75.6 1.0 CG1 K:VAL225 4.6 75.6 1.0 CA K:VAL225 4.6 75.6 1.0 CB K:ASP223 4.6 82.4 1.0 N K:THR227 4.7 74.7 1.0 OG1 K:THR227 4.7 74.7 1.0 CB K:ASN221 4.8 83.2 1.0 CB K:GLU230 4.8 78.9 1.0 CA K:ASN221 4.8 83.2 1.0 C K:ASN221 4.9 83.2 1.0 C K:VAL226 4.9 73.3 1.0 CA K:ASP223 5.0 82.4 1.0

Calcium binding site 10 out of 12 in the Human KV4.2-KCHIP2-DPP6 Channel Complex in An Open State, Intracellular Region


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 10 of Human KV4.2-KCHIP2-DPP6 Channel Complex in An Open State, Intracellular Region within 5.0Å range: probe atom residue distance (Å) B Occ L:Ca901 b:39.2 occ:1.00 OD1 L:ASP135 2.4 39.1 1.0 O L:SER141 2.5 34.2 1.0 OD2 L:ASP146 2.5 26.8 1.0 OD1 L:ASN137 2.5 45.8 1.0 OD1 L:ASP139 2.6 41.4 1.0 OD2 L:ASP139 2.6 41.4 1.0 OD1 L:ASP146 2.6 26.8 1.0 CG L:ASP146 2.8 26.8 1.0 CG L:ASP139 2.9 41.4 1.0 CG L:ASP135 3.5 39.1 1.0 CG L:ASN137 3.5 45.8 1.0 C L:SER141 3.7 34.2 1.0 ND2 L:ASN137 3.8 45.8 1.0 CA L:VAL142 4.1 26.6 1.0 N L:SER143 4.1 24.2 1.0 CB L:ASP146 4.2 26.8 1.0 CA L:ASP135 4.2 39.1 1.0 OD2 L:ASP135 4.3 39.1 1.0 CB L:ASP135 4.3 39.1 1.0 N L:VAL142 4.3 26.6 1.0 OG L:SER143 4.4 24.2 1.0 CB L:ASP139 4.4 41.4 1.0 C L:ASP135 4.6 39.1 1.0 C L:VAL142 4.6 26.6 1.0 N L:THR136 4.6 44.1 1.0 N L:ASN137 4.7 45.8 1.0 CA L:SER141 4.8 34.2 1.0 CB L:ASN137 4.9 45.8 1.0 N L:ASP139 4.9 41.4 1.0 N L:SER141 4.9 34.2 1.0 CB L:SER143 4.9 24.2 1.0

W.Ye, H.Zhao, Y.Dai, Y.Wang, Y.H.Lo, L.Y.Jan, C.H.Lee. Activation and Closed-State Inactivation Mechanisms of the Human Voltage-Gated K V 4 Channel Complexes. Mol.Cell V. 82 2427 2022.
ISSN: ISSN 1097-2765
PubMed: 35597238
DOI: 10.1016/J.MOLCEL.2022.04.032