Calcium in PDB 7usw: Structure of Expanded C. Elegans Tmc-1 Complex
Calcium Binding Sites:
The binding sites of Calcium atom in the Structure of Expanded C. Elegans Tmc-1 Complex
(pdb code 7usw). This binding sites where shown within
5.0 Angstroms radius around Calcium atom.
In total 8 binding sites of Calcium where determined in the
Structure of Expanded C. Elegans Tmc-1 Complex, PDB code: 7usw:
Jump to Calcium binding site number:
1;
2;
3;
4;
5;
6;
7;
8;
Calcium binding site 1 out
of 8 in 7usw
Go back to
Calcium Binding Sites List in 7usw
Calcium binding site 1 out
of 8 in the Structure of Expanded C. Elegans Tmc-1 Complex
Mono view
Stereo pair view
|
A full contact list of Calcium with other atoms in the Ca binding
site number 1 of Structure of Expanded C. Elegans Tmc-1 Complex within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
A:Ca1301
b:44.9
occ:1.00
|
OD2
|
A:ASP683
|
3.3
|
37.6
|
1.0
|
OG1
|
A:THR687
|
3.4
|
23.3
|
1.0
|
CD2
|
A:LEU760
|
3.9
|
38.8
|
1.0
|
OD1
|
A:ASP683
|
4.0
|
33.1
|
1.0
|
CG
|
A:ASP683
|
4.0
|
29.2
|
1.0
|
CB
|
A:HIS731
|
4.0
|
17.0
|
1.0
|
CB
|
A:THR687
|
4.3
|
18.6
|
1.0
|
CE
|
A:LYS756
|
4.4
|
28.9
|
1.0
|
O
|
A:HIS731
|
4.4
|
27.9
|
1.0
|
CG2
|
A:THR687
|
4.4
|
18.1
|
1.0
|
NZ
|
A:LYS756
|
4.5
|
30.6
|
1.0
|
C
|
A:HIS731
|
4.6
|
17.1
|
1.0
|
CG
|
A:HIS731
|
4.6
|
24.5
|
1.0
|
CD1
|
A:LEU760
|
4.6
|
42.0
|
1.0
|
CA
|
A:HIS731
|
4.8
|
9.7
|
1.0
|
CB
|
A:ASN735
|
4.9
|
25.0
|
1.0
|
CG
|
A:LEU760
|
4.9
|
39.9
|
1.0
|
NE2
|
A:HIS404
|
5.0
|
20.6
|
1.0
|
O
|
A:ASP683
|
5.0
|
21.3
|
1.0
|
|
Calcium binding site 2 out
of 8 in 7usw
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Calcium Binding Sites List in 7usw
Calcium binding site 2 out
of 8 in the Structure of Expanded C. Elegans Tmc-1 Complex
Mono view
Stereo pair view
|
A full contact list of Calcium with other atoms in the Ca binding
site number 2 of Structure of Expanded C. Elegans Tmc-1 Complex within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
A:Ca1302
b:45.7
occ:1.00
|
OD2
|
A:ASP695
|
2.5
|
46.9
|
1.0
|
NH1
|
A:ARG764
|
3.4
|
30.7
|
1.0
|
ND2
|
A:ASN772
|
3.4
|
33.4
|
1.0
|
CG
|
A:ASP695
|
3.6
|
42.2
|
1.0
|
CD1
|
A:PHE723
|
3.8
|
30.4
|
1.0
|
CE1
|
A:PHE723
|
3.9
|
17.4
|
1.0
|
OD1
|
A:ASP695
|
4.0
|
37.2
|
1.0
|
CB
|
A:ALA767
|
4.2
|
12.2
|
1.0
|
CG
|
A:ASN772
|
4.3
|
30.4
|
1.0
|
OD1
|
A:ASN772
|
4.4
|
25.4
|
1.0
|
CD
|
A:ARG764
|
4.5
|
22.3
|
1.0
|
CZ
|
A:ARG764
|
4.6
|
27.9
|
1.0
|
ND2
|
A:ASN728
|
4.8
|
21.0
|
1.0
|
N
|
A:VAL768
|
4.8
|
31.0
|
1.0
|
CB
|
A:ASP695
|
4.9
|
31.9
|
1.0
|
C
|
A:ALA767
|
4.9
|
19.5
|
1.0
|
NE
|
A:ARG764
|
5.0
|
21.4
|
1.0
|
CG1
|
A:ILE691
|
5.0
|
25.7
|
1.0
|
CG
|
A:PHE723
|
5.0
|
22.6
|
1.0
|
|
Calcium binding site 3 out
of 8 in 7usw
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Calcium Binding Sites List in 7usw
Calcium binding site 3 out
of 8 in the Structure of Expanded C. Elegans Tmc-1 Complex
Mono view
Stereo pair view
|
A full contact list of Calcium with other atoms in the Ca binding
site number 3 of Structure of Expanded C. Elegans Tmc-1 Complex within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
B:Ca1302
b:44.7
occ:1.00
|
OD2
|
B:ASP683
|
3.3
|
38.0
|
1.0
|
OG1
|
B:THR687
|
3.4
|
21.8
|
1.0
|
CD2
|
B:LEU760
|
3.9
|
36.9
|
1.0
|
OD1
|
B:ASP683
|
4.0
|
30.9
|
1.0
|
CB
|
B:HIS731
|
4.0
|
16.1
|
1.0
|
CG
|
B:ASP683
|
4.0
|
28.2
|
1.0
|
CB
|
B:THR687
|
4.3
|
18.2
|
1.0
|
O
|
B:HIS731
|
4.4
|
27.6
|
1.0
|
CE
|
B:LYS756
|
4.4
|
26.9
|
1.0
|
CG2
|
B:THR687
|
4.4
|
18.1
|
1.0
|
NZ
|
B:LYS756
|
4.5
|
29.1
|
1.0
|
C
|
B:HIS731
|
4.6
|
17.6
|
1.0
|
CG
|
B:HIS731
|
4.6
|
23.7
|
1.0
|
CD1
|
B:LEU760
|
4.6
|
40.3
|
1.0
|
CA
|
B:HIS731
|
4.8
|
11.3
|
1.0
|
CB
|
B:ASN735
|
4.9
|
23.8
|
1.0
|
CG
|
B:LEU760
|
4.9
|
37.9
|
1.0
|
NE2
|
B:HIS404
|
4.9
|
20.0
|
1.0
|
O
|
B:ASP683
|
5.0
|
19.4
|
1.0
|
|
Calcium binding site 4 out
of 8 in 7usw
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Calcium Binding Sites List in 7usw
Calcium binding site 4 out
of 8 in the Structure of Expanded C. Elegans Tmc-1 Complex
Mono view
Stereo pair view
|
A full contact list of Calcium with other atoms in the Ca binding
site number 4 of Structure of Expanded C. Elegans Tmc-1 Complex within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
B:Ca1303
b:46.1
occ:1.00
|
OD2
|
B:ASP695
|
2.5
|
46.2
|
1.0
|
NH1
|
B:ARG764
|
3.4
|
28.8
|
1.0
|
ND2
|
B:ASN772
|
3.4
|
32.4
|
1.0
|
CG
|
B:ASP695
|
3.6
|
41.7
|
1.0
|
CD1
|
B:PHE723
|
3.8
|
29.7
|
1.0
|
CE1
|
B:PHE723
|
3.9
|
17.5
|
1.0
|
OD1
|
B:ASP695
|
4.0
|
37.1
|
1.0
|
CB
|
B:ALA767
|
4.2
|
11.5
|
1.0
|
CG
|
B:ASN772
|
4.3
|
29.8
|
1.0
|
OD1
|
B:ASN772
|
4.4
|
23.7
|
1.0
|
CD
|
B:ARG764
|
4.5
|
20.9
|
1.0
|
CZ
|
B:ARG764
|
4.6
|
26.3
|
1.0
|
ND2
|
B:ASN728
|
4.8
|
22.3
|
1.0
|
N
|
B:VAL768
|
4.8
|
30.5
|
1.0
|
CB
|
B:ASP695
|
4.9
|
31.1
|
1.0
|
C
|
B:ALA767
|
4.9
|
17.7
|
1.0
|
NE
|
B:ARG764
|
5.0
|
20.2
|
1.0
|
CG1
|
B:ILE691
|
5.0
|
25.4
|
1.0
|
|
Calcium binding site 5 out
of 8 in 7usw
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Calcium Binding Sites List in 7usw
Calcium binding site 5 out
of 8 in the Structure of Expanded C. Elegans Tmc-1 Complex
Mono view
Stereo pair view
|
A full contact list of Calcium with other atoms in the Ca binding
site number 5 of Structure of Expanded C. Elegans Tmc-1 Complex within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
C:Ca301
b:62.5
occ:1.00
|
O
|
C:LEU136
|
2.3
|
43.1
|
1.0
|
OD2
|
C:ASP141
|
2.3
|
60.8
|
1.0
|
OD1
|
C:ASP134
|
2.4
|
64.4
|
1.0
|
OD1
|
C:ASP132
|
2.4
|
64.6
|
1.0
|
OD2
|
C:ASP132
|
2.5
|
67.0
|
1.0
|
CG
|
C:ASP132
|
2.8
|
64.1
|
1.0
|
CG
|
C:ASP134
|
3.4
|
59.5
|
1.0
|
CG
|
C:ASP141
|
3.4
|
62.4
|
1.0
|
C
|
C:LEU136
|
3.5
|
46.9
|
1.0
|
OD2
|
C:ASP134
|
3.7
|
56.5
|
1.0
|
N
|
C:GLY138
|
4.0
|
51.2
|
1.0
|
OD1
|
C:ASP141
|
4.1
|
67.2
|
1.0
|
CB
|
C:ASP132
|
4.3
|
65.8
|
1.0
|
CA
|
C:LEU136
|
4.3
|
43.9
|
1.0
|
N
|
C:LEU136
|
4.4
|
43.7
|
1.0
|
N
|
C:LEU137
|
4.4
|
51.5
|
1.0
|
CB
|
C:LEU136
|
4.5
|
51.7
|
1.0
|
CB
|
C:ASP141
|
4.5
|
55.3
|
1.0
|
CA
|
C:LEU137
|
4.5
|
47.6
|
1.0
|
CB
|
C:ASP130
|
4.6
|
41.2
|
1.0
|
N
|
C:ASP134
|
4.7
|
57.0
|
1.0
|
CB
|
C:ASP134
|
4.7
|
55.5
|
1.0
|
C
|
C:LEU137
|
4.8
|
46.8
|
1.0
|
N
|
C:ASP132
|
4.8
|
70.5
|
1.0
|
CA
|
C:GLY138
|
4.9
|
51.6
|
1.0
|
N
|
C:GLY133
|
4.9
|
57.9
|
1.0
|
|
Calcium binding site 6 out
of 8 in 7usw
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Calcium Binding Sites List in 7usw
Calcium binding site 6 out
of 8 in the Structure of Expanded C. Elegans Tmc-1 Complex
Mono view
Stereo pair view
|
A full contact list of Calcium with other atoms in the Ca binding
site number 6 of Structure of Expanded C. Elegans Tmc-1 Complex within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
C:Ca302
b:77.4
occ:1.00
|
OD1
|
C:ASP171
|
2.4
|
79.9
|
1.0
|
O
|
C:SER177
|
2.4
|
62.7
|
1.0
|
CG
|
C:ASP171
|
3.4
|
75.7
|
1.0
|
OD1
|
C:ASN179
|
3.6
|
57.6
|
1.0
|
C
|
C:SER177
|
3.6
|
58.1
|
1.0
|
OD2
|
C:ASP171
|
4.0
|
75.3
|
1.0
|
CB
|
C:ASP175
|
4.0
|
75.3
|
1.0
|
CA
|
C:ILE178
|
4.2
|
52.9
|
1.0
|
N
|
C:ASP173
|
4.3
|
74.7
|
1.0
|
CB
|
C:ASP173
|
4.3
|
79.1
|
1.0
|
N
|
C:ILE178
|
4.3
|
51.3
|
1.0
|
N
|
C:ASN179
|
4.3
|
58.5
|
1.0
|
N
|
C:LEU172
|
4.4
|
74.8
|
1.0
|
N
|
C:ASP175
|
4.4
|
72.8
|
1.0
|
CB
|
C:ASP171
|
4.5
|
69.4
|
1.0
|
CG
|
C:ASN179
|
4.5
|
57.5
|
1.0
|
CA
|
C:ASP171
|
4.5
|
72.3
|
1.0
|
N
|
C:SER177
|
4.6
|
62.6
|
1.0
|
CG
|
C:ASP173
|
4.6
|
78.1
|
1.0
|
CA
|
C:SER177
|
4.7
|
59.5
|
1.0
|
C
|
C:ILE178
|
4.7
|
50.4
|
1.0
|
CA
|
C:ASP173
|
4.7
|
77.5
|
1.0
|
CA
|
C:ASP175
|
4.8
|
74.9
|
1.0
|
OD2
|
C:ASP173
|
4.8
|
75.3
|
1.0
|
N
|
C:GLY174
|
4.9
|
65.7
|
1.0
|
C
|
C:ASP171
|
5.0
|
74.5
|
1.0
|
|
Calcium binding site 7 out
of 8 in 7usw
Go back to
Calcium Binding Sites List in 7usw
Calcium binding site 7 out
of 8 in the Structure of Expanded C. Elegans Tmc-1 Complex
Mono view
Stereo pair view
|
A full contact list of Calcium with other atoms in the Ca binding
site number 7 of Structure of Expanded C. Elegans Tmc-1 Complex within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
E:Ca301
b:60.2
occ:1.00
|
O
|
E:LEU136
|
2.3
|
43.6
|
1.0
|
OD2
|
E:ASP141
|
2.3
|
61.9
|
1.0
|
OD1
|
E:ASP134
|
2.4
|
63.8
|
1.0
|
OD1
|
E:ASP132
|
2.5
|
64.2
|
1.0
|
OD2
|
E:ASP132
|
2.5
|
65.2
|
1.0
|
CG
|
E:ASP132
|
2.8
|
63.0
|
1.0
|
CG
|
E:ASP134
|
3.4
|
59.5
|
1.0
|
CG
|
E:ASP141
|
3.4
|
63.4
|
1.0
|
C
|
E:LEU136
|
3.5
|
47.4
|
1.0
|
OD2
|
E:ASP134
|
3.7
|
55.6
|
1.0
|
N
|
E:GLY138
|
4.0
|
51.5
|
1.0
|
OD1
|
E:ASP141
|
4.1
|
68.0
|
1.0
|
CB
|
E:ASP132
|
4.3
|
64.6
|
1.0
|
CA
|
E:LEU136
|
4.3
|
43.9
|
1.0
|
N
|
E:LEU136
|
4.4
|
43.8
|
1.0
|
N
|
E:LEU137
|
4.4
|
52.0
|
1.0
|
CB
|
E:LEU136
|
4.5
|
51.7
|
1.0
|
CB
|
E:ASP141
|
4.5
|
55.5
|
1.0
|
CA
|
E:LEU137
|
4.5
|
48.3
|
1.0
|
CB
|
E:ASP130
|
4.6
|
40.1
|
1.0
|
N
|
E:ASP134
|
4.7
|
56.5
|
1.0
|
CB
|
E:ASP134
|
4.7
|
55.1
|
1.0
|
C
|
E:LEU137
|
4.8
|
47.2
|
1.0
|
N
|
E:ASP132
|
4.8
|
69.5
|
1.0
|
CA
|
E:GLY138
|
4.8
|
52.5
|
1.0
|
N
|
E:GLY133
|
4.9
|
57.8
|
1.0
|
|
Calcium binding site 8 out
of 8 in 7usw
Go back to
Calcium Binding Sites List in 7usw
Calcium binding site 8 out
of 8 in the Structure of Expanded C. Elegans Tmc-1 Complex
Mono view
Stereo pair view
|
A full contact list of Calcium with other atoms in the Ca binding
site number 8 of Structure of Expanded C. Elegans Tmc-1 Complex within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
E:Ca302
b:77.8
occ:1.00
|
OD1
|
E:ASP171
|
2.4
|
81.0
|
1.0
|
O
|
E:SER177
|
2.4
|
63.7
|
1.0
|
CG
|
E:ASP171
|
3.4
|
76.8
|
1.0
|
OD1
|
E:ASN179
|
3.6
|
58.7
|
1.0
|
C
|
E:SER177
|
3.6
|
59.5
|
1.0
|
OD2
|
E:ASP171
|
4.0
|
76.5
|
1.0
|
CB
|
E:ASP175
|
4.0
|
73.5
|
1.0
|
CA
|
E:ILE178
|
4.2
|
54.4
|
1.0
|
N
|
E:ASP173
|
4.2
|
72.8
|
1.0
|
CB
|
E:ASP173
|
4.3
|
77.1
|
1.0
|
N
|
E:ILE178
|
4.3
|
53.0
|
1.0
|
N
|
E:ASN179
|
4.3
|
59.6
|
1.0
|
N
|
E:LEU172
|
4.4
|
73.9
|
1.0
|
N
|
E:ASP175
|
4.4
|
72.3
|
1.0
|
CB
|
E:ASP171
|
4.5
|
70.2
|
1.0
|
CG
|
E:ASN179
|
4.5
|
58.4
|
1.0
|
CA
|
E:ASP171
|
4.5
|
73.3
|
1.0
|
N
|
E:SER177
|
4.6
|
63.7
|
1.0
|
CG
|
E:ASP173
|
4.6
|
76.4
|
1.0
|
CA
|
E:SER177
|
4.7
|
60.7
|
1.0
|
C
|
E:ILE178
|
4.7
|
52.0
|
1.0
|
CA
|
E:ASP173
|
4.7
|
76.1
|
1.0
|
CA
|
E:ASP175
|
4.8
|
73.7
|
1.0
|
OD2
|
E:ASP173
|
4.8
|
73.5
|
1.0
|
N
|
E:GLY174
|
4.9
|
63.9
|
1.0
|
C
|
E:ASP171
|
5.0
|
75.5
|
1.0
|
|
Reference:
H.Jeong,
S.Clark,
A.Goehring,
S.Dehghani-Ghahnaviyeh,
A.Rasouli,
E.Tajkhorshid,
E.Gouaux.
Structures of the Tmc-1 Complex Illuminate Mechanosensory Transduction. Nature V. 610 796 2022.
ISSN: ESSN 1476-4687
PubMed: 36224384
DOI: 10.1038/S41586-022-05314-8
Page generated: Fri Jul 19 05:05:42 2024
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