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Calcium in PDB 7vfs: Human N-Type Voltage Gated Calcium Channel CAV2.2-ALPHA2/DELTA1-BETA1 Complex, Apo State

Calcium Binding Sites:

The binding sites of Calcium atom in the Human N-Type Voltage Gated Calcium Channel CAV2.2-ALPHA2/DELTA1-BETA1 Complex, Apo State (pdb code 7vfs). This binding sites where shown within 5.0 Angstroms radius around Calcium atom.
In total 2 binding sites of Calcium where determined in the Human N-Type Voltage Gated Calcium Channel CAV2.2-ALPHA2/DELTA1-BETA1 Complex, Apo State, PDB code: 7vfs:
Jump to Calcium binding site number: 1; 2;

Calcium binding site 1 out of 2 in 7vfs

Go back to Calcium Binding Sites List in 7vfs
Calcium binding site 1 out of 2 in the Human N-Type Voltage Gated Calcium Channel CAV2.2-ALPHA2/DELTA1-BETA1 Complex, Apo State


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 1 of Human N-Type Voltage Gated Calcium Channel CAV2.2-ALPHA2/DELTA1-BETA1 Complex, Apo State within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Ca2423

b:39.3
occ:1.00
OE2 A:GLU314 2.4 24.3 1.0
OE1 A:GLU663 2.5 25.4 1.0
OE2 A:GLU1365 2.5 24.6 1.0
OE1 A:GLU1365 2.5 24.6 1.0
OE1 A:GLU314 2.8 24.3 1.0
CD A:GLU1365 2.9 24.6 1.0
CD A:GLU314 2.9 24.3 1.0
CD A:GLU663 3.4 25.4 1.0
O A:GLY1654 3.4 22.9 1.0
OE2 A:GLU663 3.7 25.4 1.0
OE1 A:GLU1655 3.8 25.8 1.0
CG A:GLU1365 4.4 24.6 1.0
CG A:GLU314 4.4 24.3 1.0
C A:GLY1654 4.6 22.9 1.0
CA A:GLU663 4.7 25.4 1.0
CG A:GLU663 4.7 25.4 1.0
O A:MET313 4.7 24.8 1.0
N A:ASP664 4.7 27.9 1.0
CA A:GLU1655 4.9 25.8 1.0
CA A:GLU1365 4.9 24.6 1.0
CB A:GLU663 4.9 25.4 1.0
CD A:GLU1655 4.9 25.8 1.0
N A:ALA1656 4.9 23.5 1.0
CA A:GLU314 5.0 24.3 1.0

Calcium binding site 2 out of 2 in 7vfs

Go back to Calcium Binding Sites List in 7vfs
Calcium binding site 2 out of 2 in the Human N-Type Voltage Gated Calcium Channel CAV2.2-ALPHA2/DELTA1-BETA1 Complex, Apo State


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 2 of Human N-Type Voltage Gated Calcium Channel CAV2.2-ALPHA2/DELTA1-BETA1 Complex, Apo State within 5.0Å range:
probe atom residue distance (Å) B Occ
B:Ca1201

b:42.5
occ:1.00
OG B:SER263 2.3 33.0 1.0
OG1 B:THR331 2.4 42.5 1.0
OD2 A:ASP122 2.5 36.1 1.0
OG B:SER261 3.0 31.1 1.0
CB B:SER263 3.5 33.0 1.0
CG A:ASP122 3.5 36.1 1.0
CB B:THR331 3.6 42.5 1.0
OD1 A:ASP122 3.8 36.1 1.0
CB B:SER261 3.9 31.1 1.0
OD2 B:ASP259 4.1 33.3 1.0
CG2 B:THR331 4.3 42.5 1.0
N B:SER263 4.5 33.0 1.0
OD1 B:ASP363 4.5 33.5 1.0
O B:GLY364 4.6 34.0 1.0
CA B:SER263 4.6 33.0 1.0
OD1 B:ASP259 4.7 33.3 1.0
N B:THR331 4.7 42.5 1.0
CA B:THR331 4.8 42.5 1.0
CG B:ASP259 4.8 33.3 1.0
CB A:ASP122 4.8 36.1 1.0
OD2 B:ASP363 5.0 33.5 1.0

Reference:

Y.Dong, Y.Gao, S.Xu, Y.Wang, Z.Yu, Y.Li, B.Li, T.Yuan, B.Yang, X.C.Zhang, D.Jiang, Z.Huang, Y.Zhao. Closed-State Inactivation and Pore-Blocker Modulation Mechanisms of Human CAV2.2. Cell Rep V. 37 2021.
ISSN: ESSN 2211-1247
DOI: 10.1016/J.CELREP.2021.109931
Page generated: Fri Jul 19 05:18:22 2024

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