Calcium in PDB 7vfv: Human N-Type Voltage Gated Calcium Channel CAV2.2-ALPHA2/DELTA1-BETA1 Complex, Bound to PD173212

The binding sites of Calcium atom in the Human N-Type Voltage Gated Calcium Channel CAV2.2-ALPHA2/DELTA1-BETA1 Complex, Bound to PD173212 (pdb code 7vfv). This binding sites where shown within 5.0 Angstroms radius around Calcium atom.
In total 2 binding sites of Calcium where determined in the Human N-Type Voltage Gated Calcium Channel CAV2.2-ALPHA2/DELTA1-BETA1 Complex, Bound to PD173212, PDB code: 7vfv:
Jump to Calcium binding site number: 1; 2;

Calcium binding site 1 out of 2 in the Human N-Type Voltage Gated Calcium Channel CAV2.2-ALPHA2/DELTA1-BETA1 Complex, Bound to PD173212


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 1 of Human N-Type Voltage Gated Calcium Channel CAV2.2-ALPHA2/DELTA1-BETA1 Complex, Bound to PD173212 within 5.0Å range: probe atom residue distance (Å) B Occ A:Ca2422 b:40.1 occ:1.00 OE2 A:GLU1365 2.4 33.0 1.0 OE2 A:GLU314 2.4 33.2 1.0 OE1 A:GLU663 2.5 35.6 1.0 OE1 A:GLU1365 2.5 33.0 1.0 CD A:GLU1365 2.8 33.0 1.0 CD A:GLU314 3.4 33.2 1.0 O A:GLY1654 3.4 32.0 1.0 CD A:GLU663 3.6 35.6 1.0 OE1 A:GLU314 3.6 33.2 1.0 OE2 A:GLU663 4.0 35.6 1.0 OE1 A:GLU1655 4.1 33.9 1.0 CG A:GLU1365 4.3 33.0 1.0 C A:GLY1654 4.6 32.0 1.0 O A:GLY1364 4.7 32.2 1.0 CG A:GLU314 4.7 33.2 1.0 CA A:GLU1365 4.7 33.0 1.0 CA A:GLU663 4.8 35.6 1.0 CG A:GLU663 4.8 35.6 1.0 N A:ASP664 4.9 36.8 1.0 CB A:GLU663 4.9 35.6 1.0 CA A:GLU1655 5.0 33.9 1.0

Calcium binding site 2 out of 2 in the Human N-Type Voltage Gated Calcium Channel CAV2.2-ALPHA2/DELTA1-BETA1 Complex, Bound to PD173212


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 2 of Human N-Type Voltage Gated Calcium Channel CAV2.2-ALPHA2/DELTA1-BETA1 Complex, Bound to PD173212 within 5.0Å range: probe atom residue distance (Å) B Occ B:Ca1201 b:54.5 occ:1.00 OG B:SER263 2.4 41.9 1.0 OD2 A:ASP122 2.4 49.9 1.0 OG1 B:THR331 2.5 50.0 1.0 OG B:SER261 3.2 41.4 1.0 CG A:ASP122 3.4 49.9 1.0 CB B:SER263 3.5 41.9 1.0 OD1 A:ASP122 3.6 49.9 1.0 CB B:THR331 3.7 50.0 1.0 CB B:SER261 4.1 41.4 1.0 N B:SER263 4.5 41.9 1.0 CG2 B:THR331 4.5 50.0 1.0 N B:THR331 4.6 50.0 1.0 CA B:SER263 4.6 41.9 1.0 OD2 B:ASP259 4.6 37.8 1.0 CB A:ASP122 4.7 49.9 1.0 OD1 B:ASP363 4.7 43.9 1.0 CA B:THR331 4.8 50.0 1.0 O B:GLY364 4.8 47.6 1.0 CD1 A:LEU118 4.9 43.9 1.0

Y.Dong, Y.Gao, S.Xu, Y.Wang, Z.Yu, Y.Li, B.Li, T.Yuan, B.Yang, X.C.Zhang, D.Jiang, Z.Huang, Y.Zhao. Closed-State Inactivation and Pore-Blocker Modulation Mechanisms of Human CAV2.2. Cell Rep V. 37 2021.
ISSN: ESSN 2211-1247
DOI: 10.1016/J.CELREP.2021.109931