Calcium in PDB 7wll: Cryoem Structure of Human Low-Voltage Activated T-Type Calcium Channel CAV3.3 in Complex with Pimozide(Pmz)

The structure of Cryoem Structure of Human Low-Voltage Activated T-Type Calcium Channel CAV3.3 in Complex with Pimozide(Pmz) also contains other interesting chemical elements:

Fluorine

(F)

2 atoms

The binding sites of Calcium atom in the Cryoem Structure of Human Low-Voltage Activated T-Type Calcium Channel CAV3.3 in Complex with Pimozide(Pmz) (pdb code 7wll). This binding sites where shown within 5.0 Angstroms radius around Calcium atom.
In total 2 binding sites of Calcium where determined in the Cryoem Structure of Human Low-Voltage Activated T-Type Calcium Channel CAV3.3 in Complex with Pimozide(Pmz), PDB code: 7wll:
Jump to Calcium binding site number: 1; 2;

Calcium binding site 1 out of 2 in the Cryoem Structure of Human Low-Voltage Activated T-Type Calcium Channel CAV3.3 in Complex with Pimozide(Pmz)


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 1 of Cryoem Structure of Human Low-Voltage Activated T-Type Calcium Channel CAV3.3 in Complex with Pimozide(Pmz) within 5.0Å range: probe atom residue distance (Å) B Occ A:Ca2306 b:52.6 occ:1.00 O A:GLY1677 3.2 46.9 1.0 O A:GLN820 3.5 47.0 1.0 O A:LYS1379 3.7 48.4 1.0 OE1 A:GLU357 3.7 44.1 1.0 O14 A:3PE2302 3.7 60.0 1.0 O A:LEU356 4.3 41.0 1.0 C A:GLY1677 4.3 46.9 1.0 C A:GLN820 4.7 47.0 1.0 C A:LYS1379 4.8 48.4 1.0 CA A:CA2307 4.8 56.0 1.0 CD A:GLU357 4.9 44.1 1.0 OD1 A:ASP1380 5.0 48.6 1.0 O A:THR1676 5.0 43.3 1.0

Calcium binding site 2 out of 2 in the Cryoem Structure of Human Low-Voltage Activated T-Type Calcium Channel CAV3.3 in Complex with Pimozide(Pmz)


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 2 of Cryoem Structure of Human Low-Voltage Activated T-Type Calcium Channel CAV3.3 in Complex with Pimozide(Pmz) within 5.0Å range: probe atom residue distance (Å) B Occ A:Ca2307 b:56.0 occ:1.00 OE2 A:GLU357 2.4 44.1 1.0 OE1 A:GLU357 2.7 44.1 1.0 CD A:GLU357 2.9 44.1 1.0 OD1 A:ASP1380 3.1 48.6 1.0 OE2 A:GLU821 3.8 49.1 1.0 N A:ASN1679 4.2 51.8 1.0 CG A:GLU821 4.2 49.1 1.0 CG A:ASP1380 4.3 48.6 1.0 CD A:GLU821 4.4 49.1 1.0 CG A:GLU357 4.4 44.1 1.0 OD1 A:ASP1678 4.4 48.3 1.0 N A:ASP822 4.6 51.0 1.0 N A:GLY1381 4.8 47.0 1.0 OD1 A:ASP822 4.8 51.0 1.0 CA A:CA2306 4.8 52.6 1.0 CA A:GLU821 4.8 49.1 1.0 CA A:ASN1679 4.9 51.8 1.0 CA A:ASP1678 4.9 48.3 1.0 O A:GLY1677 5.0 46.9 1.0

L.He, Z.Yu, Z.Geng, Z.Huang, C.Zhang, Y.Dong, Y.Gao, Y.Wang, Q.Chen, L.Sun, X.Ma, B.Huang, X.Wang, Y.Zhao. Structure, Gating, and Pharmacology of Human Ca V 3.3 Channel. Nat Commun V. 13 2084 2022.
ISSN: ESSN 2041-1723
PubMed: 35440630
DOI: 10.1038/S41467-022-29728-0