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Calcium in PDB 7x6c: Cryo-Em Structure of the Human TRPC5 Ion Channel in Lipid Nanodiscs, CLASS1

Other elements in 7x6c:

The structure of Cryo-Em Structure of the Human TRPC5 Ion Channel in Lipid Nanodiscs, CLASS1 also contains other interesting chemical elements:

Zinc (Zn) 4 atoms

Calcium Binding Sites:

The binding sites of Calcium atom in the Cryo-Em Structure of the Human TRPC5 Ion Channel in Lipid Nanodiscs, CLASS1 (pdb code 7x6c). This binding sites where shown within 5.0 Angstroms radius around Calcium atom.
In total 4 binding sites of Calcium where determined in the Cryo-Em Structure of the Human TRPC5 Ion Channel in Lipid Nanodiscs, CLASS1, PDB code: 7x6c:
Jump to Calcium binding site number: 1; 2; 3; 4;

Calcium binding site 1 out of 4 in 7x6c

Go back to Calcium Binding Sites List in 7x6c
Calcium binding site 1 out of 4 in the Cryo-Em Structure of the Human TRPC5 Ion Channel in Lipid Nanodiscs, CLASS1


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 1 of Cryo-Em Structure of the Human TRPC5 Ion Channel in Lipid Nanodiscs, CLASS1 within 5.0Å range:
probe atom residue distance (Å) B Occ
C:Ca805

b:34.0
occ:1.00
OE2 C:GLU418 2.5 37.3 1.0
OD1 C:ASN436 2.6 37.6 1.0
OD2 C:ASP439 2.6 27.4 1.0
CD C:GLU418 3.4 37.3 1.0
OE1 C:GLU418 3.6 37.3 1.0
NH2 C:ARG492 3.7 19.5 1.0
CG C:ASN436 3.8 37.6 1.0
CG C:ASP439 3.8 27.4 1.0
CB C:ASP439 4.5 27.4 1.0
ND2 C:ASN436 4.6 37.6 1.0
CA C:ASN436 4.8 37.6 1.0
OD1 C:ASP439 4.8 27.4 1.0
CB C:ASN436 4.8 37.6 1.0
CG C:GLU418 4.8 37.3 1.0

Calcium binding site 2 out of 4 in 7x6c

Go back to Calcium Binding Sites List in 7x6c
Calcium binding site 2 out of 4 in the Cryo-Em Structure of the Human TRPC5 Ion Channel in Lipid Nanodiscs, CLASS1


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 2 of Cryo-Em Structure of the Human TRPC5 Ion Channel in Lipid Nanodiscs, CLASS1 within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Ca805

b:34.9
occ:1.00
OE2 A:GLU418 2.5 36.9 1.0
OD1 A:ASN436 2.6 38.1 1.0
OD2 A:ASP439 2.6 27.6 1.0
CD A:GLU418 3.4 36.9 1.0
OE1 A:GLU418 3.6 36.9 1.0
NH2 A:ARG492 3.7 19.1 1.0
CG A:ASN436 3.8 38.1 1.0
CG A:ASP439 3.8 27.6 1.0
CB A:ASP439 4.5 27.6 1.0
ND2 A:ASN436 4.6 38.1 1.0
CA A:ASN436 4.8 38.1 1.0
OD1 A:ASP439 4.8 27.6 1.0
CB A:ASN436 4.8 38.1 1.0
CG A:GLU418 4.8 36.9 1.0

Calcium binding site 3 out of 4 in 7x6c

Go back to Calcium Binding Sites List in 7x6c
Calcium binding site 3 out of 4 in the Cryo-Em Structure of the Human TRPC5 Ion Channel in Lipid Nanodiscs, CLASS1


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 3 of Cryo-Em Structure of the Human TRPC5 Ion Channel in Lipid Nanodiscs, CLASS1 within 5.0Å range:
probe atom residue distance (Å) B Occ
B:Ca806

b:33.3
occ:1.00
OE2 B:GLU418 2.5 38.5 1.0
OD1 B:ASN436 2.6 38.7 1.0
OD2 B:ASP439 2.6 28.1 1.0
CD B:GLU418 3.4 38.5 1.0
OE1 B:GLU418 3.6 38.5 1.0
NH2 B:ARG492 3.7 18.1 1.0
CG B:ASN436 3.8 38.7 1.0
CG B:ASP439 3.8 28.1 1.0
CB B:ASP439 4.5 28.1 1.0
ND2 B:ASN436 4.6 38.7 1.0
CA B:ASN436 4.8 38.7 1.0
OD1 B:ASP439 4.8 28.1 1.0
CB B:ASN436 4.8 38.7 1.0
CG B:GLU418 4.8 38.5 1.0

Calcium binding site 4 out of 4 in 7x6c

Go back to Calcium Binding Sites List in 7x6c
Calcium binding site 4 out of 4 in the Cryo-Em Structure of the Human TRPC5 Ion Channel in Lipid Nanodiscs, CLASS1


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 4 of Cryo-Em Structure of the Human TRPC5 Ion Channel in Lipid Nanodiscs, CLASS1 within 5.0Å range:
probe atom residue distance (Å) B Occ
D:Ca806

b:34.6
occ:1.00
OE2 D:GLU418 2.5 38.3 1.0
OD1 D:ASN436 2.6 38.5 1.0
OD2 D:ASP439 2.6 28.1 1.0
CD D:GLU418 3.4 38.3 1.0
OE1 D:GLU418 3.6 38.3 1.0
NH2 D:ARG492 3.7 18.3 1.0
CG D:ASN436 3.8 38.5 1.0
CG D:ASP439 3.8 28.1 1.0
CB D:ASP439 4.5 28.1 1.0
ND2 D:ASN436 4.6 38.5 1.0
CA D:ASN436 4.8 38.5 1.0
OD1 D:ASP439 4.8 28.1 1.0
CB D:ASN436 4.8 38.5 1.0
CG D:GLU418 4.8 38.3 1.0

Reference:

J.Won, J.Kim, H.Jeong, J.Kim, S.Feng, B.Jeong, M.Kwak, J.Ko, W.Im, I.So, H.H.Lee. Molecular Architecture of the G Alpha I -Bound TRPC5 Ion Channel. Nat Commun V. 14 2550 2023.
ISSN: ESSN 2041-1723
PubMed: 37137991
DOI: 10.1038/S41467-023-38281-3
Page generated: Fri Jul 19 05:55:44 2024

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