Calcium in PDB 7xlq: Structure of Human R-Type Voltage-Gated CAV2.3-ALPHA2/DELTA1-BETA1 Channel Complex in the Ligand-Free (Apo) State

The binding sites of Calcium atom in the Structure of Human R-Type Voltage-Gated CAV2.3-ALPHA2/DELTA1-BETA1 Channel Complex in the Ligand-Free (Apo) State (pdb code 7xlq). This binding sites where shown within 5.0 Angstroms radius around Calcium atom.
In total 2 binding sites of Calcium where determined in the Structure of Human R-Type Voltage-Gated CAV2.3-ALPHA2/DELTA1-BETA1 Channel Complex in the Ligand-Free (Apo) State, PDB code: 7xlq:
Jump to Calcium binding site number: 1; 2;

Calcium binding site 1 out of 2 in the Structure of Human R-Type Voltage-Gated CAV2.3-ALPHA2/DELTA1-BETA1 Channel Complex in the Ligand-Free (Apo) State


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 1 of Structure of Human R-Type Voltage-Gated CAV2.3-ALPHA2/DELTA1-BETA1 Channel Complex in the Ligand-Free (Apo) State within 5.0Å range: probe atom residue distance (Å) B Occ A:Ca2413 b:28.2 occ:1.00 OE1 A:GLU1372 2.3 15.2 1.0 OE2 A:GLU309 2.8 14.4 1.0 O A:GLY1662 2.9 15.4 1.0 OE1 A:GLU309 3.1 14.4 1.0 CD A:GLU309 3.3 14.4 1.0 CD A:GLU1372 3.6 15.2 1.0 CG A:GLU657 3.8 15.2 1.0 O A:MET308 4.1 13.3 1.0 C A:GLY1662 4.1 15.4 1.0 OE2 A:GLU1372 4.4 15.2 1.0 CG A:GLU1372 4.5 15.2 1.0 OE2 A:GLU657 4.6 15.2 1.0 CB A:GLU657 4.7 15.2 1.0 OE1 A:GLU1663 4.7 15.0 1.0 CG A:GLU309 4.7 14.4 1.0 CA A:GLU657 4.8 15.2 1.0 CD A:GLU657 4.8 15.2 1.0 CA A:GLU1663 5.0 15.0 1.0 N A:GLU1663 5.0 15.0 1.0 CA A:GLY1662 5.0 15.4 1.0 CA A:GLU309 5.0 14.4 1.0 C A:MET308 5.0 13.3 1.0

Calcium binding site 2 out of 2 in the Structure of Human R-Type Voltage-Gated CAV2.3-ALPHA2/DELTA1-BETA1 Channel Complex in the Ligand-Free (Apo) State


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 2 of Structure of Human R-Type Voltage-Gated CAV2.3-ALPHA2/DELTA1-BETA1 Channel Complex in the Ligand-Free (Apo) State within 5.0Å range: probe atom residue distance (Å) B Occ D:Ca1206 b:33.1 occ:1.00 OD2 A:ASP116 2.5 28.5 1.0 OG D:SER263 2.5 21.6 1.0 OG D:SER261 2.8 22.4 1.0 OG1 D:THR331 3.2 29.7 1.0 CB D:SER263 3.4 21.6 1.0 CG A:ASP116 3.5 28.5 1.0 OD1 A:ASP116 3.8 28.5 1.0 CB D:SER261 3.8 22.4 1.0 N D:SER263 4.1 21.6 1.0 CB D:THR331 4.3 29.7 1.0 CA D:SER263 4.3 21.6 1.0 OD2 D:ASP259 4.6 20.9 1.0 CD2 A:LEU112 4.7 23.9 1.0 OD1 D:ASP363 4.8 22.3 1.0 CB A:ASP116 4.8 28.5 1.0 N D:GLY262 4.9 22.0 1.0 OD2 D:ASP363 4.9 22.3 1.0

Y.Gao, S.Xu, X.Cui, H.Xu, Y.Qiu, Y.Wei, Y.Dong, B.Zhu, C.Peng, S.Liu, X.C.Zhang, J.Sun, Z.Huang, Y.Zhao. Molecular Insights Into the Gating Mechanisms of Voltage-Gated Calcium Channel Ca V 2.3. Nat Commun V. 14 516 2023.
ISSN: ESSN 2041-1723
PubMed: 36720859
DOI: 10.1038/S41467-023-36260-2