Calcium in PDB 7yg5: Structure of Human R-Type Voltage-Gated CAV2.3-ALPHA2/DELTA1-BETA1 Channel Complex in the Topiramate-Bound State

The binding sites of Calcium atom in the Structure of Human R-Type Voltage-Gated CAV2.3-ALPHA2/DELTA1-BETA1 Channel Complex in the Topiramate-Bound State (pdb code 7yg5). This binding sites where shown within 5.0 Angstroms radius around Calcium atom.
In total 2 binding sites of Calcium where determined in the Structure of Human R-Type Voltage-Gated CAV2.3-ALPHA2/DELTA1-BETA1 Channel Complex in the Topiramate-Bound State, PDB code: 7yg5:
Jump to Calcium binding site number: 1; 2;

Calcium binding site 1 out of 2 in the Structure of Human R-Type Voltage-Gated CAV2.3-ALPHA2/DELTA1-BETA1 Channel Complex in the Topiramate-Bound State


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 1 of Structure of Human R-Type Voltage-Gated CAV2.3-ALPHA2/DELTA1-BETA1 Channel Complex in the Topiramate-Bound State within 5.0Å range: probe atom residue distance (Å) B Occ A:Ca2415 b:31.5 occ:1.00 OE1 A:GLU1372 2.4 19.7 1.0 OE1 A:GLU309 2.9 22.9 1.0 OE2 A:GLU309 3.0 22.9 1.0 O A:GLY1662 3.1 20.9 1.0 CD A:GLU309 3.3 22.9 1.0 CD A:GLU1372 3.3 19.7 1.0 OE2 A:GLU1372 3.4 19.7 1.0 OE2 A:GLU657 4.1 22.4 1.0 CG A:GLU657 4.1 22.4 1.0 O A:MET308 4.2 21.3 1.0 C A:GLY1662 4.3 20.9 1.0 OE1 A:GLU1663 4.3 21.4 1.0 CA A:GLU1663 4.5 21.4 1.0 CD A:GLU657 4.6 22.4 1.0 CG A:GLU1372 4.7 19.7 1.0 CA A:GLU309 4.7 22.9 1.0 CG A:GLU309 4.7 22.9 1.0 N A:GLU1663 4.8 21.4 1.0 CD A:GLU1663 4.9 21.4 1.0

Calcium binding site 2 out of 2 in the Structure of Human R-Type Voltage-Gated CAV2.3-ALPHA2/DELTA1-BETA1 Channel Complex in the Topiramate-Bound State


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 2 of Structure of Human R-Type Voltage-Gated CAV2.3-ALPHA2/DELTA1-BETA1 Channel Complex in the Topiramate-Bound State within 5.0Å range: probe atom residue distance (Å) B Occ D:Ca1201 b:47.0 occ:1.00 OG1 D:THR331 2.4 37.8 1.0 OD2 A:ASP116 2.5 38.4 1.0 OG D:SER263 2.6 28.6 1.0 OG D:SER261 2.7 29.8 1.0 CB D:THR331 3.6 37.8 1.0 CB D:SER263 3.6 28.6 1.0 CG A:ASP116 3.6 38.4 1.0 CB D:SER261 3.7 29.8 1.0 OD1 A:ASP116 4.0 38.4 1.0 N D:SER263 4.2 28.6 1.0 OD2 D:ASP259 4.3 26.3 1.0 CG2 D:THR331 4.4 37.8 1.0 CA D:SER263 4.5 28.6 1.0 N D:THR331 4.6 37.8 1.0 OD1 D:ASP363 4.6 31.0 1.0 CA D:THR331 4.7 37.8 1.0 OD1 D:ASP259 4.7 26.3 1.0 N D:GLY262 4.9 30.2 1.0 CB A:ASP116 4.9 38.4 1.0 CA D:SER261 4.9 29.8 1.0 OD2 D:ASP363 5.0 31.0 1.0 CG D:ASP259 5.0 26.3 1.0

Y.Gao, Y.Zhao. Structural Insights Into Allosteric Effects of Antiepileptic Drug Topiramate on CAV2.3 Channel. To Be Published.