Calcium in PDB 8bw6: Titin Fniii-Domain I110 (I/A6) From the Mir Region

All present enzymatic activity of Titin Fniii-Domain I110 (I/A6) From the Mir Region:
2.7.11.1;

The structure of Titin Fniii-Domain I110 (I/A6) From the Mir Region, PDB code: 8bw6 was solved by O.Mayans, J.R.Fleming, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	42.44 / 1.95
Space group	P 41 21 2
Cell size a, b, c (Å), α, β, γ (°)	45.86, 45.86, 112.02, 90, 90, 90
R / Rfree (%)	21.7 / 25.4

The binding sites of Calcium atom in the Titin Fniii-Domain I110 (I/A6) From the Mir Region (pdb code 8bw6). This binding sites where shown within 5.0 Angstroms radius around Calcium atom.
In total only one binding site of Calcium was determined in the Titin Fniii-Domain I110 (I/A6) From the Mir Region, PDB code: 8bw6:

Calcium binding site 1 out of 1 in the Titin Fniii-Domain I110 (I/A6) From the Mir Region


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 1 of Titin Fniii-Domain I110 (I/A6) From the Mir Region within 5.0Å range: probe atom residue distance (Å) B Occ A:Ca105 b:60.5 occ:1.00 OE2 A:GLU62 2.3 54.2 1.0 OD2 A:ASP60 2.4 54.7 1.0 O A:HOH226 2.5 56.6 1.0 OD1 A:ASP60 2.7 52.3 1.0 CG A:ASP60 2.9 58.0 1.0 CD A:GLU62 3.5 53.8 1.0 CG A:GLU62 4.0 51.6 1.0 O A:HOH229 4.4 61.5 1.0 CB A:ASP60 4.5 49.9 1.0 OE1 A:GLU62 4.5 51.5 1.0 O A:HOH212 4.7 66.0 1.0

C.Stergiou, R.Williams, J.R.Fleming, V.Zouvelou, E.Ninou, F.Andreetta, E.Rinaldi, O.Simoncini, R.Mantegazza, J.Bogomolovas, J.Tzartos, S.Labeit, O.Mayans, S.Tzartos. Immunological and Structural Characterization of Titin Main Immunogenic Region; I110 Domain Is the Target of Titin Antibodies in Myasthenia Gravis Biomedicines 2023.
ISSN: ESSN 2227-9059
DOI: 10.3390/BIOMEDICINES11020449