Calcium in PDB 8ccy: Human Heparan Sulfate N-Deacetylase-N-Sulfotransferase 1 in Complex with Calcium and 3'-Phosphoadenosine-5'-Phosphosulfate

All present enzymatic activity of Human Heparan Sulfate N-Deacetylase-N-Sulfotransferase 1 in Complex with Calcium and 3'-Phosphoadenosine-5'-Phosphosulfate:
2.8.2.8;

The binding sites of Calcium atom in the Human Heparan Sulfate N-Deacetylase-N-Sulfotransferase 1 in Complex with Calcium and 3'-Phosphoadenosine-5'-Phosphosulfate (pdb code 8ccy). This binding sites where shown within 5.0 Angstroms radius around Calcium atom.
In total 2 binding sites of Calcium where determined in the Human Heparan Sulfate N-Deacetylase-N-Sulfotransferase 1 in Complex with Calcium and 3'-Phosphoadenosine-5'-Phosphosulfate, PDB code: 8ccy:
Jump to Calcium binding site number: 1; 2;

Calcium binding site 1 out of 2 in the Human Heparan Sulfate N-Deacetylase-N-Sulfotransferase 1 in Complex with Calcium and 3'-Phosphoadenosine-5'-Phosphosulfate


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 1 of Human Heparan Sulfate N-Deacetylase-N-Sulfotransferase 1 in Complex with Calcium and 3'-Phosphoadenosine-5'-Phosphosulfate within 5.0Å range: probe atom residue distance (Å) B Occ A:Ca902 b:95.0 occ:1.00 OD1 A:ASP320 2.3 81.8 1.0 NE2 A:HIS389 2.4 54.9 1.0 NE2 A:HIS393 2.4 61.8 1.0 CE1 A:HIS389 2.9 50.9 1.0 CG A:ASP320 3.3 81.6 1.0 O A:PRO431 3.3 68.5 1.0 CE1 A:HIS393 3.3 62.0 1.0 CD2 A:HIS393 3.4 61.9 1.0 O A:HOH1008 3.4 51.9 1.0 CA A:PRO431 3.6 66.2 1.0 OD2 A:ASP320 3.6 85.0 1.0 CD2 A:HIS389 3.6 49.3 1.0 OD2 A:ASP319 3.6 80.6 1.0 CA A:CA903 3.7 96.2 1.0 C A:PRO431 3.9 66.4 1.0 CG A:ASP319 4.0 77.2 1.0 ND1 A:HIS389 4.1 53.1 1.0 CB A:PRO431 4.1 65.9 1.0 CB A:ASP319 4.4 74.5 1.0 ND1 A:HIS393 4.5 63.2 1.0 CG A:HIS389 4.5 50.4 1.0 N A:ASP320 4.5 73.3 1.0 CG A:HIS393 4.6 56.0 1.0 CB A:ASP320 4.6 79.5 1.0 OD1 A:ASP319 4.7 78.0 1.0 N A:PRO431 4.8 65.3 1.0 CA A:ASP320 4.8 75.8 1.0 O A:ALA430 4.8 78.8 1.0

Calcium binding site 2 out of 2 in the Human Heparan Sulfate N-Deacetylase-N-Sulfotransferase 1 in Complex with Calcium and 3'-Phosphoadenosine-5'-Phosphosulfate


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 2 of Human Heparan Sulfate N-Deacetylase-N-Sulfotransferase 1 in Complex with Calcium and 3'-Phosphoadenosine-5'-Phosphosulfate within 5.0Å range: probe atom residue distance (Å) B Occ A:Ca903 b:96.2 occ:1.00 OD2 A:ASP320 3.6 85.0 1.0 CA A:CA902 3.7 95.0 1.0 OG1 A:THR490 3.7 129.6 1.0 NE2 A:HIS529 3.8 93.9 1.0 CD2 A:HIS529 3.9 96.4 1.0 O A:PRO431 4.0 68.5 1.0 CG A:ASP320 4.4 81.6 1.0 OD1 A:ASP320 4.5 81.8 1.0 O A:HOH1008 4.6 51.9 1.0 CE1 A:HIS529 4.8 94.3 1.0 CE1 A:HIS393 4.8 62.0 1.0 CG A:HIS529 4.8 96.4 1.0 NE2 A:HIS393 4.9 61.8 1.0 OD2 A:ASP319 4.9 80.6 1.0

C.J.Mycroft-West, S.Abdelkarim, H.M.E.Duyvesteyn, M.A.Skidmore, R.J.Owens, L.Wu. Structural and Mechanistic Characterization of Bifunctional Heparan Sulfate N-Deacetylase-N-Sulfotransferase 1 To Be Published.