Calcium in PDB 8fd7: Structure of the Human L-Type Voltage-Gated Calcium Channel CAV1.2 Complexed with Gabapentin

The structure of Structure of the Human L-Type Voltage-Gated Calcium Channel CAV1.2 Complexed with Gabapentin also contains other interesting chemical elements:

Sodium

(Na)

1 atom

The binding sites of Calcium atom in the Structure of the Human L-Type Voltage-Gated Calcium Channel CAV1.2 Complexed with Gabapentin (pdb code 8fd7). This binding sites where shown within 5.0 Angstroms radius around Calcium atom.
In total 3 binding sites of Calcium where determined in the Structure of the Human L-Type Voltage-Gated Calcium Channel CAV1.2 Complexed with Gabapentin, PDB code: 8fd7:
Jump to Calcium binding site number: 1; 2; 3;

Calcium binding site 1 out of 3 in the Structure of the Human L-Type Voltage-Gated Calcium Channel CAV1.2 Complexed with Gabapentin


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 1 of Structure of the Human L-Type Voltage-Gated Calcium Channel CAV1.2 Complexed with Gabapentin within 5.0Å range: probe atom residue distance (Å) B Occ D:Ca1210 b:30.0 occ:1.00 OG D:SER265 2.4 64.8 1.0 OG1 D:THR333 2.4 64.7 1.0 OG D:SER263 2.9 57.4 1.0 OD2 K:ASP151 3.6 95.4 1.0 CB D:THR333 3.6 59.6 1.0 CB D:SER265 3.7 63.8 1.0 CB D:SER263 3.9 55.8 1.0 CG2 D:THR333 3.9 56.8 1.0 OD2 D:ASP261 4.0 47.9 1.0 OD1 D:ASP365 4.4 64.1 1.0 OD2 D:ASP365 4.6 63.8 1.0 OD1 D:ASP261 4.6 48.8 1.0 O D:GLY366 4.7 57.7 1.0 CA D:SER265 4.7 62.0 1.0 CG K:ASP151 4.7 100.0 1.0 CG D:ASP261 4.7 47.5 1.0 N D:SER265 4.7 58.9 1.0 CA D:THR333 4.8 58.2 1.0 CG D:ASP365 5.0 64.0 1.0 N D:THR333 5.0 52.6 1.0

Calcium binding site 2 out of 3 in the Structure of the Human L-Type Voltage-Gated Calcium Channel CAV1.2 Complexed with Gabapentin


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 2 of Structure of the Human L-Type Voltage-Gated Calcium Channel CAV1.2 Complexed with Gabapentin within 5.0Å range: probe atom residue distance (Å) B Occ K:Ca1706 b:30.0 occ:1.00 O28 K:WO91701 3.6 0.0 1.0 C23 K:WO91701 4.0 0.0 1.0 O K:MET362 4.1 69.6 1.0 O26 K:WO91701 4.1 0.0 1.0 O K:GLY705 4.1 59.3 1.0 C21 K:WO91701 4.3 0.0 1.0 C29 K:WO91701 4.3 0.0 1.0 OE1 K:GLU363 4.3 83.0 1.0 P25 K:WO91701 4.3 0.0 1.0 O K:THR361 4.5 54.0 1.0 O24 K:WO91701 4.7 0.0 1.0 C K:GLY705 4.7 56.2 1.0 C22 K:WO91701 4.7 0.0 1.0 CA K:CA1707 4.9 30.0 1.0 C K:MET362 5.0 64.8 1.0 O32 K:WO91701 5.0 0.0 1.0

Calcium binding site 3 out of 3 in the Structure of the Human L-Type Voltage-Gated Calcium Channel CAV1.2 Complexed with Gabapentin


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 3 of Structure of the Human L-Type Voltage-Gated Calcium Channel CAV1.2 Complexed with Gabapentin within 5.0Å range: probe atom residue distance (Å) B Occ K:Ca1707 b:30.0 occ:1.00 OE1 K:GLU363 2.5 83.0 1.0 OE2 K:GLU1115 3.0 69.8 1.0 CD K:GLU363 3.2 86.7 1.0 OE2 K:GLU363 3.2 86.8 1.0 OE1 K:GLU706 3.2 69.0 1.0 OE1 K:GLU1115 3.8 74.1 1.0 CD K:GLU1115 3.8 72.4 1.0 O K:GLY1415 3.8 87.7 1.0 CD K:GLU706 4.1 65.0 1.0 OE2 K:GLU706 4.4 66.4 1.0 OE1 K:GLU1416 4.5 92.7 1.0 N K:ASP707 4.5 50.7 1.0 CG K:GLU363 4.6 79.4 1.0 OE2 K:GLU1416 4.6 92.6 1.0 CA K:GLU706 4.8 58.8 1.0 CD K:GLU1416 4.8 91.8 1.0 O K:PHE1114 4.8 63.5 1.0 O K:MET362 4.8 69.6 1.0 CA K:GLU363 4.9 77.0 1.0 O K:GLY705 4.9 59.3 1.0 CA K:CA1706 4.9 30.0 1.0

Z.Chen, A.Mondal, D.L.Minor. Structural Basis For CAVALPHA2DELTA:Gabapentin Binding To Be Published.