Calcium in PDB 8fnb: Crystal Structure of the C-Terminal Fg Domain of Human Tnc with the Mutations Y2140H and S2164H

The structure of Crystal Structure of the C-Terminal Fg Domain of Human Tnc with the Mutations Y2140H and S2164H, PDB code: 8fnb was solved by S.Bouyain, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	34.83 / 1.80
Space group	C 1 2 1
Cell size a, b, c (Å), α, β, γ (°)	106.045, 101.561, 56.667, 90, 122.35, 90
R / Rfree (%)	15.2 / 17.4

The binding sites of Calcium atom in the Crystal Structure of the C-Terminal Fg Domain of Human Tnc with the Mutations Y2140H and S2164H (pdb code 8fnb). This binding sites where shown within 5.0 Angstroms radius around Calcium atom.
In total 2 binding sites of Calcium where determined in the Crystal Structure of the C-Terminal Fg Domain of Human Tnc with the Mutations Y2140H and S2164H, PDB code: 8fnb:
Jump to Calcium binding site number: 1; 2;

Calcium binding site 1 out of 2 in the Crystal Structure of the C-Terminal Fg Domain of Human Tnc with the Mutations Y2140H and S2164H


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 1 of Crystal Structure of the C-Terminal Fg Domain of Human Tnc with the Mutations Y2140H and S2164H within 5.0Å range: probe atom residue distance (Å) B Occ A:Ca2301 b:29.5 occ:1.00 O A:THR2134 2.3 27.5 1.0 O A:ALA2132 2.3 30.6 1.0 OD2 A:ASP2128 2.4 28.6 1.0 OD1 A:ASP2130 2.4 25.7 1.0 O A:HOH2462 2.4 30.3 1.0 O A:HOH2548 2.4 35.1 1.0 OD1 A:ASP2128 2.6 26.1 1.0 CG A:ASP2128 2.8 30.4 1.0 CG A:ASP2130 3.2 27.5 1.0 HA A:ASN2135 3.4 34.3 1.0 C A:ALA2132 3.4 30.9 1.0 OD2 A:ASP2130 3.5 28.1 1.0 C A:THR2134 3.5 30.8 1.0 H A:ALA2132 3.6 38.3 1.0 HB3 A:ALA2132 3.8 34.4 1.0 H A:ASP2130 3.9 31.5 1.0 N A:ALA2132 4.1 31.9 1.0 C A:ILE2133 4.1 31.2 1.0 CA A:ASN2135 4.2 28.5 1.0 HA A:ILE2133 4.2 33.5 1.0 CA A:ALA2132 4.2 31.2 1.0 N A:ASN2135 4.2 27.8 1.0 O A:ASP2130 4.2 28.1 1.0 H A:CYS2136 4.3 31.4 1.0 O A:HOH2450 4.3 39.1 1.0 CB A:ASP2128 4.3 28.8 1.0 N A:THR2134 4.3 29.2 1.0 O A:ILE2133 4.3 36.6 1.0 N A:ILE2133 4.4 29.2 1.0 O A:HOH2425 4.4 32.8 1.0 C A:ASP2130 4.4 28.0 1.0 CB A:ALA2132 4.5 28.7 1.0 CA A:ILE2133 4.5 27.9 1.0 N A:ASP2130 4.5 26.2 1.0 CB A:ASP2130 4.5 25.5 1.0 CA A:THR2134 4.5 30.7 1.0 HB3 A:ASP2128 4.5 34.5 1.0 H A:THR2134 4.6 35.0 1.0 CA A:ASP2130 4.7 26.4 1.0 HB2 A:ASP2128 4.7 34.5 1.0 HB2 A:ASN2135 4.8 34.4 1.0 N A:CYS2136 4.9 26.1 1.0 HB1 A:ALA2132 5.0 34.4 1.0 HA A:THR2134 5.0 36.8 1.0

Calcium binding site 2 out of 2 in the Crystal Structure of the C-Terminal Fg Domain of Human Tnc with the Mutations Y2140H and S2164H


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 2 of Crystal Structure of the C-Terminal Fg Domain of Human Tnc with the Mutations Y2140H and S2164H within 5.0Å range: probe atom residue distance (Å) B Occ B:Ca2301 b:29.6 occ:1.00 OD2 B:ASP2128 2.3 28.6 1.0 O B:THR2134 2.3 28.3 1.0 O B:ALA2132 2.4 30.1 1.0 OD1 B:ASP2130 2.4 23.5 1.0 O B:HOH2410 2.4 30.9 1.0 O B:HOH2538 2.5 37.5 1.0 OD1 B:ASP2128 2.6 26.3 1.0 CG B:ASP2128 2.8 30.0 1.0 CG B:ASP2130 3.2 25.5 1.0 HA B:ASN2135 3.4 33.1 1.0 OD2 B:ASP2130 3.4 27.6 1.0 C B:ALA2132 3.4 32.4 1.0 C B:THR2134 3.5 30.2 1.0 H B:ALA2132 3.6 38.0 1.0 HB3 B:ALA2132 3.7 33.0 1.0 H B:ASP2130 3.9 34.0 1.0 N B:ALA2132 4.1 31.6 1.0 C B:ILE2133 4.1 29.9 1.0 HA B:ILE2133 4.2 31.5 1.0 O B:ASP2130 4.2 27.1 1.0 CA B:ASN2135 4.2 27.6 1.0 CA B:ALA2132 4.2 30.2 1.0 N B:ASN2135 4.3 28.5 1.0 H B:CYS2136 4.3 27.9 1.0 O B:ILE2133 4.3 36.5 1.0 CB B:ASP2128 4.3 27.9 1.0 N B:THR2134 4.3 27.5 1.0 O B:HOH2409 4.4 37.3 1.0 C B:ASP2130 4.4 27.8 1.0 N B:ILE2133 4.4 28.8 1.0 O B:HOH2431 4.4 36.9 1.0 CB B:ALA2132 4.4 27.5 1.0 O B:HOH2591 4.4 49.4 1.0 N B:ASP2130 4.5 28.3 1.0 CB B:ASP2130 4.5 24.4 1.0 CA B:ILE2133 4.5 26.2 1.0 CA B:THR2134 4.5 29.0 1.0 HB3 B:ASP2128 4.6 33.5 1.0 H B:THR2134 4.7 33.0 1.0 CA B:ASP2130 4.7 24.0 1.0 HB2 B:ASP2128 4.7 33.5 1.0 HB2 B:ASN2135 4.8 35.0 1.0 HB1 B:ALA2132 4.9 33.0 1.0 N B:CYS2136 5.0 23.2 1.0 HB3 B:ASP2130 5.0 29.3 1.0 HA B:THR2134 5.0 34.8 1.0

A.Sinha, J.Kawakami, K.S.Cole, A.Ladutska, M.Y.Nguyen, M.S.Zalmai, B.L.Holder, V.M.Broerman, R.T.Matthews, S.Bouyain. Protein-Protein Interactions Between Tenascin-R and Rptp Zeta /Phosphacan Are Critical to Maintain the Architecture of Perineuronal Nets. J.Biol.Chem. 04952 2023.
ISSN: ESSN 1083-351X
PubMed: 37356715
DOI: 10.1016/J.JBC.2023.104952