Calcium in PDB 8h9y: Crystal Structure of Voltage-Gated Sodium Channel Navab N49K/L176Q Mutant in Calcium Ion Condition

The structure of Crystal Structure of Voltage-Gated Sodium Channel Navab N49K/L176Q Mutant in Calcium Ion Condition, PDB code: 8h9y was solved by K.Irie, Y.Oda, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	29.78 / 3.40
Space group	I 4 2 2
Cell size a, b, c (Å), α, β, γ (°)	127.94, 127.94, 201.92, 90, 90, 90
R / Rfree (%)	25.4 / 26.4

The binding sites of Calcium atom in the Crystal Structure of Voltage-Gated Sodium Channel Navab N49K/L176Q Mutant in Calcium Ion Condition (pdb code 8h9y). This binding sites where shown within 5.0 Angstroms radius around Calcium atom.
In total 2 binding sites of Calcium where determined in the Crystal Structure of Voltage-Gated Sodium Channel Navab N49K/L176Q Mutant in Calcium Ion Condition, PDB code: 8h9y:
Jump to Calcium binding site number: 1; 2;

Calcium binding site 1 out of 2 in the Crystal Structure of Voltage-Gated Sodium Channel Navab N49K/L176Q Mutant in Calcium Ion Condition


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 1 of Crystal Structure of Voltage-Gated Sodium Channel Navab N49K/L176Q Mutant in Calcium Ion Condition within 5.0Å range: probe atom residue distance (Å) B Occ A:Ca1312 b:41.3 occ:1.00 OE1 A:GLN1176 3.0 41.0 1.0 O6' A:LMT1301 3.6 55.5 1.0 CD A:GLN1176 4.0 36.8 1.0 CA A:CA1313 4.2 44.4 0.2 CB A:GLN1176 4.5 23.0 1.0 NE2 A:GLN1176 4.7 44.6 1.0 C6' A:LMT1301 4.8 59.2 1.0 CG A:GLN1176 4.9 32.8 1.0

Calcium binding site 2 out of 2 in the Crystal Structure of Voltage-Gated Sodium Channel Navab N49K/L176Q Mutant in Calcium Ion Condition


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 2 of Crystal Structure of Voltage-Gated Sodium Channel Navab N49K/L176Q Mutant in Calcium Ion Condition within 5.0Å range: probe atom residue distance (Å) B Occ A:Ca1313 b:44.4 occ:0.25 CA A:CA1312 4.2 41.3 1.0 O A:HOH1412 4.4 25.1 0.2

K.Irie, Y.Oda, T.Sumikama, A.Oshima, Y.Fujiyoshi. The Structural Basis of Divalent Cation Block in A Tetrameric Prokaryotic Sodium Channel. Nat Commun V. 14 4236 2023.
ISSN: ESSN 2041-1723
PubMed: 37454189
DOI: 10.1038/S41467-023-39987-0